Lipid Luminations

Lipid Luminations

Episodes

  • Managing CVD in Women During Childbearing Years

    Aug 25, 2014 | 16 min
    Hosted by: Alan S. Brown Guest: Robert Wild What are the conditions associated with dyslipidemia pre-pregnancy that put women at greater risk for complications? What is the long term effect of having an obstetrical complication as CVD Risk for the mother and fetus? And, what is the major concern for hypertriglyceridemia in Pg and how do you treat it? Dr. Alan Brown, host, welcomes Dr. Robert A. Wild, who will address these questions and more during this discussion of Lipid Luminations. Dr. Wild is Professor of Reproductive Endocrinology, Obstetrics and Gynecology, Medicine, Family Medicine & Biostatistics and Epidemiology at the University of Oklahoma. And, he is Chief of the Gynecology Serv...
  • Broken Hearts or Broken Bones?

    Aug 18, 2014 | 17 min
    Hosted by: Alan S. Brown Guest: Janet Maxson Host Dr. Alan S. Brown welcomes Janet Maxson, NP, PhD, iPresident-Elect of the Midwest Lipid Association and the Director Women's Health at Minot Health & Wellness in Minot, North Dakota. Dr. Maxson is also a Fellow of the American Heart Association Council of Cardiovascular Nursing and the National Lipid Association. Dr. Maxson will review which calcium supplements are better for women, how much calcium is needed, and define the screening guidelines that are in place to screen women's bones in the context of heart disease. Tune in for another great interview from Lipid Luminations!    
  • Non-pharmacologic Approaches to the Metabolic Syndrome and Diabetes

    Aug 11, 2014 | 18 min
    Hosted by: Alan S. Brown Guest: Neil Stone Why is metabolic syndrome so important if it's not a disease? What have we learned from clinical trials about treating metabolic syndrome with lifestyle and/or drugs? And, what hurdles does the clinician face in trying to improve metabolic syndrome variables in the individual patient? Join Host Dr. Alan Brown as he welcomes Dr. Neil J Stone who will answer these questions and more. Dr. Stone is the Bonow Professor of Medicine at The Feinberg School of Medicine of Northwestern University and Distinguished Physician and Medical Director of the Vascular Center of the Bluhm Cardiovascular Institute of Northwestern Memorial Hospital in Chicago, Illinois.
  • HPS-2 THRIVE Data and Results

    Aug 4, 2014 | 17 min
    Hosted by: Alan S. Brown Joining host Dr. Alan Brown is Dr. John Guyton, Associate Professor of Medicine and Assistant Professor of Pathology of the Division of Medicine-Endocrinology and Metabolism at Duke University School of Medicine. Their discussion will focus on data and results from HPS-2 THRIVE, a large-scale study comparing the use of statins and niacin versus statins alone. THRIVE stands for the Treatment of HDL to Reduce the Incidence of Vascular Events.
  • New Insights on Statin Therapy for Older Patients

    Jul 28, 2014 | 17 min
    Hosted by: Alan S. Brown Is there a patient age at which statin therapy should be discontinued? Likewise, what does the current evidence tell us about initiating vs not initiating statin therapy in older patients? Joining Lipid Luminations to discuss these and other important questions is Dr. W. Virgil Brown, Charles Howard Candler Professor of Medicine Emeritus at Emory University School of Medicine in Atlanta, Georgia.
  • Treatment Options for Polycystic Ovarian Syndrome (PCOS)

    Jul 28, 2014 | 16 min
    Hosted by: Alan S. Brown Guest: Debra Friedrich Join host Dr. Alan Brown and guest Dr. Debra Friedrich on the most common endocrine disorder in women- Polycystic Ovarian Syndrome (PCOS). They will review the epidemiology, prevalance, diagnosis, long-term risks and treatment options.  Dr. Debra Friedrich, DNP, ARNP, is an Assistant Professor at the University of South Florida College of Nursing and Director of the Family Nurse Practitioner Concentration. She is a family nurse practitioner and Clinical Lipid Specialist in practice in Bradenton, Florida. Brought to you by:
  • Research Updates on Postprandial Dyslipidemia Treatment

    Jul 21, 2014 | 16 min
    Hosted by: Alan S. Brown Postprandial hypertriglyceridemia occurs when the rapid absorption of dietary fat (in the form of chylomicron triglycerides) overwhelms the body's ability to clear plasma triglyceride. In its most severe form, postprandial hypertriglyceridemia can lead to chylomicronemia and a greatly increased risk of acute, life-threatening pancreatitis. Joining host Dr. Alan Brown to talk about this condition and a trial drug treatment in research and development is Dr. Dan Meyers, one of the top winners in the Abstracts Program of the National Lipid Association's Annual Scientific Sessions. Dr. Meyers is currently a Translational Medicine Expert with Novartis Institutes of Biomed...
  • What is HoFH: Detection and Management of the Homozygous Familial Hypercholesterolemia (HoFH) Patient

    Jul 14, 2014 | 18 min
    Hosted by: Alan S. Brown Dr. Alan Brown welcomes Dr. Daniel J. Rader, Cooper-McLure Professor of Medicine and Pharmacology and Chief of the Division of Translational Medicine and Human Genetics at the Perelman School of Medicine at the University of Pennsylvania. Their discussion focuses on the clinical diagnosis, genetic complexity and prevalence of HoFH while exploring the current and novel modalities available to help HoFH patients achieve their LDL goals. 
  • Lipid Biomarker Updates: When to Move Beyond the Standard Profile

    Jul 7, 2014 | 16 min
    Hosted by: Alan S. Brown Dr. Alan Brown is joined by Dr. Thomas Dayspring, Director of Cardiovascular Education for the Foundation for Health Improvement and Technology in Richmond, VA and clinical assistant professor of medicine at the UMDNJ - NJ Medical School. He is also a Fellow of both the American College of Physicians and the National Lipid Association. The two discuss Dr. Dayspring's research on discordances between LDL-P and ApoB, two biomarkers that are otherwise thought to correlate well with one another.
  • Research Updates in Familial Hypercholesterolemia

    Jun 23, 2014 | 15 min
    Hosted by: Alan S. Brown Dr. Alan Brown is joined by Dr. Bart Duell, director of the Lipid Disorders Clinic at the Oregon Health and Sciences University and one of the top winners in the NLA Abstracts program, to discuss research updates in Familial Hypercholesterolemia (FH).
  • Health Information Technology's Impact on Adherence to Lipid Therapy

    Jun 16, 2014 | 16 min
    Hosted by: Alan S. Brown Health information technologies have evolved dramatically from simplistic documentation devices early on to sophisticated drivers of quality patient care today. This emergence is having a particularly positive effect on treatment for dyslipidemia. Joining host Dr. Alan Brown to reflect on a recent NLA manuscript of HIT's impact toward adherence to lipid therapy is Dr. Jerome Cohen, Emeritus Professor of Internal Medicine at Saint Louis University School of Medicine and Director of Preventative Cardiology Program at the Saint Louis University Health Sciences Center. Dr. Cohen has been active in cardiovascular research for more than two decades.
  • A Synopsis of the ACC/AHA Risk Assessment and Cholesterol Guidelines

    Jun 9, 2014 | 19 min
    Hosted by: Alan S. Brown Guest: Anne Goldberg Host Dr. Alan Brown is joined by Anne Goldberg, MD, Associate Professor of Medicine at Washington University School of Medicine and a member of the ACC/AHA Blood Cholesterol Guidelines Panel. Dr. Goldberg will provide a review of the panel assembled by National Heart, Lung, and Blood Institute to construct integrated guidelines for cardiovascular risk reduction.  She will also address the controversy regarding the ACC/AHA recently published risk assessment and cholesterol guidelines. Download and listen today!
  • Genetic Testing for Familial Hypercholesterolemia

    Jun 2, 2014 | 16 min
    Hosted by: Alan S. Brown Speaking with host Dr. Alan Brown on the state of genetic testing for familial hypercholesterolemia (FH) is Dr. Joshua W. Knowles, MD, PhD, Instructor of Cardiovascular Medicine at Stanford University and Attending Physician of the Stanford Center for Inherited Cardiovascular Disease Familial Hypercholesterolemia (FH) Clinic.
  • What is the Safety of Statins in Patients with Diabetes?

    Jun 2, 2014 | 13 min
    Hosted by: Alan S. Brown Guest: Kevin C. Maki At the most recent National Lipid Association (NLA) meeting, host Dr. Alan Brown welcomes Kevin Maki, PhD, FNLA, CLS, Chief Science Officer for Midwest Center for Metabolic and Cardiovascular Research and Adjunct Faculty position in Biostatistics and Applied Epidemiology at DePaul University, Chicago, IL. Drs. Brown and Maki discuss the evidence of the relationship of statin use and risk of new onset of diabetes; as well as, the relationship of statin use and the possiblity of worsening glycemia in those patients who have diabetes. What are the conclusions? What should clinicians be screening for? Download and listen to this great conversation!
  • National Lipid Association Recommendations for Patient-Centered Treatment of Dyslipidemia

    May 26, 2014 | 31 min
    Hosted by: Alan S. Brown Guests: Harold Bays, Matthew Ito, Kevin C. Maki, Carl Orringer Host Dr. Alan Brown is joined by an expert panel to discuss the NLA's latest draft document that will serve as recommendations to clinicians for treating patients with dyslipidemia. The National Lipid Association's goal was to harmonize guidelines among what has been presented in the past by the ATP panel, the American College of Cardiology/American Heart Association Guidelines, and those also released in 2013 by the International Atherosclerosis Society. The NLA reaffirms the importance of understanding targets of treatment and goals for patients. Our expert panelists: Harold Bays, MD, FNLA - Medical Dir...
  • National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia

    May 26, 2014 | 31 min
    Hosted by: Alan S. Brown Guests: Harold Bays, Matthew Ito, Kevin C. Maki, Carl Orringer Host Dr. Alan Brown is joined by an expert panel to discuss the NLA's latest draft document that will serve as recommendations to clinicians for the management of patients with dyslipidemia. The National Lipid Association's goal was to harmonize guidelines among what has been presented in the past by the ATP panel, the American College of Cardiology/American Heart Association Guidelines, and those also released in 2013 by the International Atherosclerosis Society. The NLA reaffirms the importance of understanding targets of treatment and goals for patients. Our expert panelists: Harold Bays, MD, FNLA - Me...
  • Cardiometabolic Consequences of Sitting Time

    May 19, 2014 | 17 min
    Hosted by: Alan S. Brown Host Dr. Alan Brown welcomes Dr. Marc Hamilton, Professor at Pennington Biomedical Research Center in Baton Rouge, LA. Their convesation focuses on the cardiometabolic consequences of lengthy sitting times, such as in people with "desk job careers."
  • Generics and Manufacturing: What Prescribers Need to Know

    May 12, 2014 | 19 min
    Hosted by: Alan S. Brown Joining host Dr. Alan Brown is Michael B. Bottorff, Pharm.D., Professor and Chair in the Department of Pharmacy Practice at South College School of Pharmacy in Knoxville, Tennessee. Dr. Bottorff will be reviewing generic medications, from manufacturing processes to approval measures.
  • Adiposity, Obesity, and Dyslipidemia

    May 5, 2014 | 19 min
    Hosted by: Alan S. Brown Dr. Harold Bays, Chair for the National Lipid Association's expert panel on Adiposity, Obesity, and Dyslipidemia, discusses with host Dr. Alan Brown the panel's consensus statement published in the Journal of Clinical Lipidology.
  • Underrecognition of Diabetes in Cardiology Practice

    Apr 28, 2014 | 19 min
    Hosted by: Alan S. Brown Joining Dr. Alan Brown is Revathi Balakrishnan, MD, MPH, a general cardiology fellow at NYU and winner of the NLA Young Investigator Competition. Dr. Balakrishnan's research, titled "Prevalence of unrecognized prediabetes, diabetes and metabolic syndrome in patients undergoing non-urgent PCI," found that nearly 1 out of every 10 patients admitted to the NYU cardiac catheterization lab had diabetic hemoglobin A1c levels (6.5 and over) without a prior diagnosis of diabetes. An even larger proportion had prediabetes (57%) and metabolic syndrome (54%). Put another way, only 30% of the patients undergoing PCI had a normal glycemic status on admission. Drs. Balakrishnan an...
  • An Avocado a Day: Does It Keep Heart Disease Away?

    Apr 21, 2014 | 19 min
    Hosted by: Alan S. Brown There may be something unique about the avocado, far beyond its monosaturated fat content. Li Wang, graduate student at Penn State University and winner of the NLA Young Investigator Award, investigated this notion with a clinical study monitoring the effects of eating one avocado every day on risk factors for cardiovascular disease compared to a similar moderate fat diet without avocados, an average American diet, and a low-fat diet. Tune in for this discussion revealing her thought-provoking findings.  
  • Researching Oxidized High-Density Lipoprotein in Obese Adolescents

    Apr 14, 2014 | 19 min
    Hosted by: Alan S. Brown Obesity is associated with systemic inflammation and oxidative stress, the leading steps towards development of atherosclerosis. Myloperoxidase (MPO) mediated oxidative damage of high-density lipoprotein (HDL) leads to a dysfunctional HDL which likely becomes pro-atherogenic. But, what happens in our adolescent patients? Monica Marin, MD, pediatric endocrinology fellow at the University of Oklahome Health Sciences Center and winner of the NLA Young Investigator Award, investigated the cardiovascular risk factors that are present in childhood and the importance of understanding the impact of oxidized HDL. Download and listen today!
  • Emerging LDL Therapies

    Apr 7, 2014 | 19 min
    Hosted by: Alan S. Brown Guest: Peter Toth Host Dr. Alan Brown is joined by Peter P. Toth, MD, PhD, director of preventive cardiology in Sterling Rock Falls Clinic and clinical professor at the University of Illinois School of Medicine in Peoria, Illinois. Dr. Toth is the current president of the National Lipid Association. One of the most intensively studied drugs are statins. However, will statins continue to be the miracle drugs that health care professionals and patients rely on?  What are statins current role in therapy for dyslipidemia patients? In this discussion, Dr. Toth will address these questions. He will also review the new therapies for lowering LDL and whether LDL should conti...
  • Controversy Surrounding the NHLBI Pediatric Guidelines

    Mar 31, 2014 | 18 min
    Hosted by: Alan S. Brown Guest: Samuel Gidding Guidelines are being changed continuously as new evidence is acquired and our environment us evolve. Most recently released are the NHLBI guidelines for pediatric care providers. Host Dr. Alan Brown welcomes Dr. Samuel Gidding. They will address the context to which the guidelines were developed, some of the key social and ethical issues faced by the panel, and a review of the results and the recommendations for the future. Dr. Samuel Gidding is the head of pediatric cardiology and interim director of heart failure and transplant at Nemours Cardiac Center, A. I. DuPont Hospital for Children, Wilmington, Delaware. Brought to you by:
  • Treatment Options for Polycystic Ovarian Syndrome (PCOS)

    Mar 31, 2014 |
    Hosted by: Alan S. Brown Guest: Debra Friedrich Join host Dr. Alan Brown and guest Dr. Debra Friedrich on the most common endocrine disorder in women- Polycystic Ovarian Syndrome (PCOS). They will review the epidemiology, prevalance, diagnosis, long-term risks and treatment options.  Dr. Debra Friedrich, DNP, ARNP, is an Assistant Professor at the University of South Florida College of Nursing and Director of the Family Nurse Practitioner Concentration. She is a family nurse practitioner and Clinical Lipid Specialist in practice in Bradenton, Florida. Brought to you by:
  • Changing Nutritional Needs Throughout the Lifetime

    Dec 18, 2013 | 17 min
    On this new edition of Lipid Lumoinations, host Dr. Alan Brown welcomes Dr. Rebecca Reeves, adjunct Assistant Professor of The University of Texas School of Public Health. Dr. Reeves will discuss the guidleines for children and adolescents as recommended by the Dietary Guidelines Advisory Committee. and review the nutrition guidelines for adults from the  AHA, Dietary Guidelines for Americans 2010, and ATP III Therapeutic Lifestyle Change.
  • Understanding Why Patients Discontinue Statin Therapy

    Dec 18, 2013 | 19 min
    Statins play a critical role in reducing the risk of heart disease. Not only are the benefits greatly appreciated by both physicians and patients, the majority of statins are also well tolerated. Despite this, many patients discontinue statin therapy against medical advice, oftentimes without notifying their doctors. For this reason, the National Lipid Association embarked on a study that used internet surveys to determine why patients discontinue their statins. This was called the USAGE Study, and its results are the subject of this discussion. Host, Dr. Alan Brown welcomes Dr. Jerome Cohen, emeritus professor of Internal Medicine at St. Louis University School of Medicine.
  • Fish Oils: Are They Still Cardioprotective?

    Dec 12, 2013 | 18 min
    Host Dr. Alan Brown welcomes Dr. William "Bill" Harris on an important discussion facing our colleagues and ptients- "Are Fish Oils still cardioprotective?". Dr. Harris will address the recent randomized trials, how the trials differ from those done in the 1990s, and how clinicians should utlize the information in treating their patients. Dr. William "Bill" Harris holds a PhD in Nutritional Biochemistry from the University of Minnesota. His research has focused on human lipid and lipoprotein metabolism, especially as they are affected by omega-3 fatty acids. He has been the principal investigator on 5 omega-3 related NIH grants, and since 2004 has been evaluating the RBC "omega-3 index" as a...
  • Fat, Exercise and Cholesterol

    Dec 12, 2013 | 15 min
    Host Dr. Alan Brown discusses fat, exercise and cholesterol with Dr. Harold Bays, medical director and president of Louisville Metabolic and Atherosclerosis Research Center, an independent research center. They look at the properties of adipose tissue — what Dr. Bays calls adiposopathy, or "sick fat." Dr. Bays says that fat cells are very active in terms of helping determine the metabolic rate and subject to dysfunction. They discuss how the location of fat cells and gender of the patient may cause differential problems and may contribute to arteriosclerosis, the effect of exercise on fat and cholesterol, and what kind of exercise is best for overweight patients.
  • Cardiometabolic Consequences of Sitting Time

    Dec 12, 2013 | 17 min
    Host Dr. Alan Brown welcomes Dr. Marc Hamilton, Professor at Pennington Biomedical Research Center in Baton Rouge, LA. Their convesation focuses on the cardiometabolic consequences of lengthy sitting times, such as in people with "desk job careers."
  • Coronary CT Angiography

    Aug 12, 2013 | 15 min
    This program reviews the guidelines for determining which patients should receive coronary CT angiography (CCTA), highlights the differences between CCTA and coronary calcium testing, and explores the overall radiation risk of serial CCTA. Dr. Alan Brown talks to guest Dr. Seth Baum, expert on electrophysiology, interventional cardiology, coronary CT angiography, and clinical lipidology, and a founding member of the Society for Cardiovascular CT.
  • Underrecognition of Diabetes in Cardiology Practice

    Jul 15, 2013 | 15 min
    Joining Dr. Alan Brown is Revathi Balakrishnan, MD, MPH, a general cardiology fellow at NYU and winner of the NLA Young Investigator Competition. Dr. Balakrishnan's research, titled "Prevalence of unrecognized prediabetes, diabetes and metabolic syndrome in patients undergoing non-urgent PCI," found that nearly 1 out of every 10 patients admitted to the NYU cardiac catheterization lab had diabetic hemoglobin A1c levels (6.5 and over) without a prior diagnosis of diabetes. An even larger proportion had prediabetes (57%) and metabolic syndrome (54%). Put another way, only 30% of the patients undergoing PCI had a normal glycemic status on admission. Drs. Balakrishnan and Brown reflect on these ...
  • Non-pharmacologic Approaches to the Metabolic Syndrome and Diabetes

    Mar 11, 2013 | 18 min
    Why is metabolic syndrome so important if it's not a disease? What have we learned from clinical trials about treating metabolic syndrome with lifestyle and/or drugs? And, what hurdles does the clinician face in trying to improve metabolic syndrome variables in the individual patient? Join Host Dr. Alan Brown as he welcomes Dr. Neil J Stone who will answer these questions and more. Dr. Stone is the Bonow Professor of Medicine at The Feinberg School of Medicine of Northwestern University and Distinguished Physician and Medical Director of the Vascular Center of the Bluhm Cardiovascular Institute of Northwestern Memorial Hospital in Chicago, Illinois.
  • Diet Controversies in Lipid Lowering & Cardiovascular Disease Prevention

    Feb 18, 2013 | 15 min
    Given that approximately one third of Americans currently have some degree of metabolic syndrome, host Dr. Alan Brown discusses the very pertinent topics of food intake, prevention, lowering lipids, and related diet issues with dietician Mary Felando. They discuss what an appropriate diet is, how physicians should react when there are changes in nutritional guidelines, and the relative importance of saturated and other dietary fats.
  • The Importance of Omega-3 Fatty Acids

    Apr 25, 2011 | 15 min
    What are the differences among fish-based omega-3s, plant-based omega-3s, and supplements? Find out what the recommendations are for individuals without known cardiovascular disease, as host Dr. Alan Brown talks with Dr. William Harris, director of the Cardiovascular Health Research Center at the Sanford School of Medicine, University of South Dakota in Sioux Falls.

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