Episode Transcript
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Speaker 1 (00:06):
You're listening to the Carrywood and Morning's podcast from news
Talk said b.
Speaker 2 (00:11):
Launching today and actually out right now is Brainstorming, a
brand new podcast from the University of Auckland's Center for
Brain Research. Journalists Clear to Law and news Talk said
be a deep dive into the human brain. Claire sits
down with world class scientists and those living with brain
disorders from dementia to CTE. It's more than just science.
(00:33):
It's about the cutting edge breakthroughs and treatments that offer
real hope for longer, healthier lives. And clear Delord joins me. Now,
very good morning to you. Good morning, carry What did
you learn by sitting down and talking with these brain scientists.
Speaker 3 (00:47):
Well, I'm certainly not a neurologist, yet almost Well, I
learned what a fascinating field it is and how dedicated
you have to be to stick at it year after year.
Because the brain is so complex and these consis are
so challenging, you are not going to get instant payback.
But boy, when you find something, when you follow that
(01:08):
trail and you can have a degree of success small
or large, it has to be the best feeling in
the world. And I also learned about the courage of
people who are living with these conditions. Also learned that
I can actually follow a little bit of it, which
is good.
Speaker 2 (01:23):
What struck me was how accessible they're like. These people
are brain search like, well not brain sweaches, but their brain,
their brain re.
Speaker 3 (01:31):
Senuorologists and their researchers. Some of them are treating patients,
some of them are solely involved in research, and they
interact fantastically at the Center of Brain Research, which brings
together more than four hundred people across the whole of
Auckland University working in various areas, but they all affect
the brain and brain research, and it's the final frontier
(01:54):
really when you think about it. You can't take a
brain out of a head and look at it, fix it,
fiddle with it. So you're actually dealing with a really
very difficult task when it comes to finding out what's
going on in there, why is this disease developing, what's
triggered it, and how do we help come up with
(02:14):
ways to treat it, let's hope one day cure it.
Speaker 2 (02:19):
That was the other thing I've had the privilege of
hearing some of them speak, and that was what I
was going to say is that even though that they
are probably in the top zero point one percent of
bright people, they're so accessible. They make the knowledge easy
to understand. They make their their research accessible to people
so that we can understand it, the ordinary lay person
(02:40):
can understand it.
Speaker 3 (02:41):
Yeah, they tell very interesting stories about their research.
Speaker 2 (02:44):
Yeah.
Speaker 3 (02:44):
I mean you could imagine it could be dry. It's not. No,
it's not fascinating.
Speaker 2 (02:49):
And the passion they have for it is conveyed as well.
Like I remember talking to professor Sir Richard full and
he was like, I can't retire, you know.
Speaker 3 (02:58):
No, he never suspect.
Speaker 2 (03:00):
His poor long suffering wife is like, please, just gonna
be a couple of years in your company. But he's like,
I can't because these new researchers come along and a
dead end that we've gone down ten years ago. They
suddenly see something, you know, they see a link that
nobody else has seen, and then we're off again, and.
Speaker 3 (03:17):
No imagined failure is wasted. Not It usually leads to
heading down another track, and on the way down what
seems like a cul de sac, you may well find
out something that's useful for later and you just tuck
it away bring it out later. But they are pretty
amazing and also fairly humble. I'm Alan Barber, who's a
neurologist who's researcher and also treats patients and has pioneered
(03:42):
clot retrieval in New Zealand. Sort of referred to himself
as a plumber. Okay, he's not a plumber. Emma Scotta,
who's doing most you'urine a disease research, referred to herself
as just a researcher. She's one of the top people
in the world in this field. She's amazing, she tells
a great story. They're just very, very good people.
Speaker 2 (04:03):
And where because of the caliber of the research is
at the Center for Brain Research Trust. It's attracting people
from around the world, isn't it whose specialty.
Speaker 3 (04:13):
Is Oh, there's an international network of people working on
all these problems. We have a niche here in Auckland
with the Center for Brain Research, with some of the
best people in the world. Some of home have come back,
like Emma from working in London and being part of
a top team there. They've come back to New Zealand.
They're attracted to working here. We have advantages here. We
(04:36):
have sort of a small village like atmosphere in some respects,
which I think is really appealing in terms of the
ease with which people work with one another and with
their patients. You know, there's a certain different, probably bedside
manner to people here.
Speaker 2 (04:52):
The other thing I was struck by when I have heard,
because I've heard a number of the guests you have
on the podcast speak at different functions is the respect
they have for their patients and for people who are
willing to donate their brains for science so that future
generations don't have to suffer the same brain afflictions. Yeah,
(05:15):
the brain Bank's amazing.
Speaker 3 (05:16):
The Brain Bank is amazing, and we lend brain tissue
to researchers all over the world because it's that good.
And the difference with the brain bank here is that
we have the histories the fucker puppa of everyone whose
brain has been donated, so they can match up behavior's
family history and the like to the condition and find
(05:37):
that little sort of edge for the research. But the
people who have taken part in the podcast, and I'd
just like to say thank you so much to them.
It has included in every instance someone either with the
condition or somebody who's speaking from the perspective of a family,
and it's incredible that living with some of the most
(05:58):
challenging and in some cases, life ending conditions that you
could encounter, that people are prepared to speak up, speak out,
tell their stories. And without that perspective, I don't think
it would have been as compelling a listener. And I
hope that your listeners, all of whom will know somebody
affected by some of the things we cover off Parkinson's, dementia, motur,
(06:23):
multiple sclerosis CTE. I hope that all of them can
learn something new and that it gives them hope, because
actually telling stories about these diseases without having the hope
would have been a bit of a armor, and I'm
really grateful we've found that bit of light. Every time,
news Talk said B.
Speaker 2 (06:42):
Will take a short break and when we come back,
we talk more about the podcast and what you can
expect to hear with Claire Delord, who is the Brain
Storing podcast host, brand new podcast from the University of
Auckland Center for Brain Research, and News Talk said B. So,
when you talk about hope, clear, does that mean that
somebody who's got a loved one living with dementia or
Parkinson's or is going to listen to the podcast and think, oh,
(07:05):
thank god, there's something I can do Tomorrow.
Speaker 3 (07:07):
Next week they'll be hearing about developments in the pipeline.
They'll be hearing from people living with these conditions, with
some of them with pointers as to how they cope
with some of the day to day difficulties. And there's
one particular breakthrough which I think holds out tremendous hope
for a small number of people because it's a relatively
(07:28):
rare but hereditary genetic disease, Huntington's disease, and it seems
that within two years, if the second and third phases
of the trials go well, there could well be one
pillar day to slow down the progression of a disease
that will otherwise take your life and that you would
(07:50):
pass on to your own children. You can actually circumvent
that possibility even if you have the gene by having
pre implantation, embryotic screening and IVF. So there is also
that hope, and that's a relatively new development. So there's
a lot of things like that that have come up
in the conversation with these various experts and have found
(08:13):
them fascinating and really inspirational.
Speaker 2 (08:16):
I suppose it's like how long is a piece of string?
But is there a kind of linear progression to this
kind of research or can all of a sudden there
be a breakthrough?
Speaker 3 (08:27):
Well, I don't know. I imagine you don't get that
many Eureka moments in this because it has been for example,
for Richard, it has been a lifetime of researching Huntington's
and other diseases. For Emma Scotta, it's been the greatest
delight of her professional research career, she says, seeing that
there was a baby born that would be free of
(08:50):
motor neuron disease, the hereditary version of it, which affects
about fifteen percent of people. So there they are very
important breakthroughs to the individuals who are affected. I can't
exactly answer your question, but I suspect it's going to
be a career in which there is going to be
no end. And I think even with the advent of
(09:13):
say AI might speed up sort of the reading of
imaging and things like that. But you'd have to ask
a neurologists this no no mad No matter how much
I've watched the pit and the good doctor, I am,
I am not a doctor or in shock.
Speaker 2 (09:26):
Message you carry yourself like thank you when it comes
to the CTE how on, Like I know that that's
a big worry for those involved in sport and contact.
Speaker 3 (09:39):
Sport, not just contact sport, I mean are the armed forces, police,
domestic domestic marlets, people who are taking repeated even sometimes
relatively small knocks to the head. So you know when
you're going to practice for the rugby. When you're a kid,
(10:00):
you can have repeated knocks. There's now there are in
our steps being taken to try and avoid that being
the case that people in practice have these repeated little knocks,
because it's not just the big concussions where you have
to stand on, this's the little knocks to the brain
that make the difference. But Helen Murray, who's a former
ice hockey international, like one of the best we've ever had,
(10:24):
is leading that research and she's got a paddock for
two paddocks full of rams actually, and some of the
rams are intact and they're in with the ladies, as
she says, they're knocking their heads together and they're able,
and then there's the control paddock of I guess they've
been newted to the other rams. So they're just living
a very quiet life, so they're able to compare the
(10:46):
outcome of the head knocking the routine head knocking of
rams to because their brains are actually similar shape to ours,
and the CTE proteins fall into the bottom of the
little cliffs that we have on our brains. So it's
amazing research and who knows what it will lead to,
but there is hoped that that could take us somewhere
(11:09):
in terms of knowing what the biomarkers are.
Speaker 2 (11:12):
Yes, so you could be diagnosed early so that something
could be done before it was too late.
Speaker 3 (11:16):
And maybe you've got a predisposition yet.
Speaker 2 (11:18):
Maybe because a lot of people play contact sport without
without ever contracting anything.
Speaker 3 (11:24):
And if you could tell early on that were people
that people were showing some of these otherwise invisible effects
by way of their bloods, that would be fantastic.
Speaker 2 (11:34):
Wouldn't it. But I remember that young there was a
young blues player who left rugby after playing rugby in
Japan because he was so nervous and so aware of
every knock that it just made rugby not worth playing
for him. He had no idea if he was going
(11:55):
to get it, and that worry consumed him so much
he left Rugby and is now training to be a
yoga practitioner.
Speaker 3 (12:03):
And yet some people still go knowingly into very high
contact sport. Boxing is the one that really kind of
gets me. I know, there are many many advantages to
it in the sense of fitness and the like, but
any sport where the aim is to knock you on
the head, it's to me, it's just like why would
you go find a brick wall pad it and do that.
Speaker 2 (12:26):
Or a ram or go watch rams? Yes, schizophrenia does
that get covered by the Center of a Brain Research Trust?
Speaker 3 (12:33):
No, we are I have not covered it.
Speaker 2 (12:36):
Is that something that they look at as well? Or
is it?
Speaker 3 (12:39):
I think so many elements of what's going on with
the brain are covered by the Center for Brain Research
that we could recite them till you go home. And
under Hannekah Hulst, who's taking over or has taken over
from Sir Richard Fall as their director, I think some
of the new research that she's going to be introducing
will be very interesting. She's a neuroscientist with a particular
(13:01):
interest in dementia and also in multiple sclerosis and some
of the impacts that having that can have, for example,
on your relationships, because if you don't know that something
is because you've got a form of dementia that or
cognitive it's not dementia, it's a cognitive effect, then you're
(13:24):
not to know that some of the things that are
going on in a relationship might just be forgetfulness based
on that not caring. Yeah, save your fortune in couple's
counseling for example.
Speaker 2 (13:36):
Yes, to know that it was actually a condition. Yeah. Not.
Somebody said, what about autism? Is there? What are you
going to be covering? Well, i'll tell you, yeah, go on,
I'll tell you just having a stab carry I'll tell
you my specialties, Thank you very much.
Speaker 3 (13:51):
Stroke, Alzheimer's, Parkinson's, multiple sclerosis, motor neurine disease, spinal cord injury,
and CTE and Huntington's of course, which we've meeked a
bit more about.
Speaker 2 (14:03):
So that'll be covered in the first series.
Speaker 3 (14:04):
In the first series, and this is I'm sure it's
going to be a plea that falls upon very willing airs.
I would love to get a second series because there
is so much.
Speaker 2 (14:14):
Yes, how did you pick? Was it availability? Was it
had well? I think prioritized well.
Speaker 3 (14:20):
In the first instance, I sort of thought of the
things that most commonly come up. I mean, so many
people are affected by Parkinson's MS, there is something about Parkinson's.
I found in the news, international news, every single day
of the week, people with different ideas or research topics
regarding it, so that one was pretty obvious. I was
(14:44):
very interested in Huntington's because I have got to know
through a really quite long association now with the Center
of Brain Research. I've got to know Mary Hyron, who
features in it and whose children, who are only two children,
have the Huntington's gene. So they were self selecting in
some cases and just very obvious. I mean, for example, stroke,
(15:05):
I thought, well, what could be about stroke? Well, actually
quite a lot.
Speaker 2 (15:08):
I'm not going to spoiler alert, No you're not going to,
but as we're well worth listening to marvelous, thank you
very much, Clear lovely to talk and you Hello that
wherever you get your podcasts, I'm going to announce it
with just that. Darling, Hello, Kerry and Clear. Thank you
for highlighting the Brainstorming podcast. As an advisor working with
clients and funer with dementia, any knowledge for your listeners
(15:31):
is invaluable. Keep up the good work.
Speaker 3 (15:33):
Thank you.
Speaker 2 (15:34):
There we go. Brainstorming is out now on iHeartRadio or.
Speaker 3 (15:38):
Clear What do We Say wherever wherever you get your podcasts.
Speaker 2 (15:41):
That's right. New episodes will be available every second Wednesday.
The first episode features sent for Brain Research founder Distinguished
Professor Sir Richard Full and Mary Hyron, who clear just
referenced whose family has been devastated by Huntington's disease.
Speaker 1 (15:57):
For more from Kerry Wood and Mornings, listen live to
news talks. It'd be from nine am weekdays, or follow
the podcast on iHeartRadio