With you MD with Dr. Joshua Engle

What happens when a physician with a background in angel investing redefines primary care from the ground up? In this episode, Dr. Joshua Engle shares how he’s bridging operations, mental health, and metabolic wellness in his cutting-edge practice, With You MD.

Summary: Dr. Joshua Engle’s path to launching a digital-first primary care practice is anything but typical—and that’s exactly what makes it powerful. In this candid and thoughtful conversation with Dr. Tudor Francu, he reveals the challenges and wins of transitioning from traditional medicine to building a new kind of healthcare business.

Dr. Engle shares how his entrepreneurial spirit, shaped by early experience in the angel investment world, eventually led him to create With You MD—a practice that prioritizes metabolic and mental health as foundational pillars of long-term patient care. He opens up about administrative setbacks, how he measures success beyond profit, and why staying focused and patient-centered is key to making real impact.

You’ll learn:

• Why he believes mental and metabolic health are critical in modern primary care

• What it’s like building a practice from scratch, from credentialing delays to staffing

• The financial and emotional lessons he’s learned on his entrepreneurial path

• Investment strategies for physicians looking to diversify beyond clinical practice

• How mentorship and transparency are helping shape a new wave of physician leaders

 

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