February 19, 2025 • 24 mins
What if your body had the ability to heal faster, reduce chronic pain, repair gut issues, and even protect your brain from stress—without relying on prescription drugs? BPC-157, a powerful regenerative peptide, has been scientifically studied for its ability to accelerate tissue repair, combat inflammation, and improve overall well-being. Yet, despite its incredible benefits, it remains largely hidden from the public.
Why? Because Big Pharma can’t patent it, meaning they can’t profit from your healing. Instead, they push expensive medications that treat symptoms rather than fixing the root cause. But now, the secret is out. Thousands of people use BPC-157 to recover from injuries, restore gut health, and reclaim vitality.
During the Q&A we answer the following question
- Do women need testosterone supplementation?
- Should guys supplement with estradiol?
- How much progesterone is too much?
If you have any burning questions you would like answered on the podcast, send them to customer-service@steelcity-trt.com, and they might get answered on the Q&A
Check out the smart link below to see what services are offered at Steel City HRT and Weight Loss, as well as discounts, blogs, and links to other social media content.
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Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
(00:00):
And this brings up a huge issue, such as manufacturing.
(00:09):
I mean, my God, people can make this shit in their bathtub if they wanted to.
Welcome to the Hormones Happen podcast, a podcast designed for individuals like you
(00:33):
who are curious about the amazing benefits of hormone replacement therapy.
I'm your host, Jeremiah, and I'm a nurse practitioner who specializes in HRT.
I've seen firsthand the debilitating effects of hormone deficiency and have personally experienced
the benefits of optimization.
My goal is to arm you with information regarding the good, the bad, and even taboo aspects
(00:56):
of HRT while answering your burning questions.
Please join me for today's episode of the Hormones Happen podcast.
(01:19):
What's going on, guys?
Welcome back to another episode of Hormones Happen.
Now, what if I told you there was a natural compound capable of accelerating wound healing,
reducing chronic pain, restoring gut health, and even protecting your brain from stress
and anxiety?
(01:40):
Imagine this compound has been around for decades, studied in labs worldwide, and yet
you've never likely heard of it.
Well, maybe you have.
If you're privy to social media, you've probably heard of this peptide called the Wolverine
peptide.
Now, what I'm talking about is the compound BPC157, a regenerative peptide that could
(02:07):
be a game changer for many men and women that are looking for help with slow recovery, nagging
injuries, digestive issues, or unexplained fatigue, BPC157 might be the secret weapon.
But the kicker is Big Pharma doesn't want you to know about it.
(02:31):
And why is that?
Because if peptides like BPC157 became mainstream, they could replace expensive prescription
drugs for pain.
That's billions of dollars in lost revenue for pharmaceutical companies.
So instead of marketing this natural compound, they keep it tucked away.
(02:51):
But let's shine some light on it.
And let's talk about how this peptide is changing the world of injuries.
So before we specifically talk about BPC157, let's take a step back and talk about what
is a peptide.
So a peptide is a single linear chain of amino acids, and when this chain is less than 50
(03:17):
amino acids in length, we call it a peptide.
When it's greater than 50, we call it a polypeptide.
And several polypeptides linked together is called a protein.
Now fun fact, BPC157 is composed of 15 amino acids.
So now that we got that out of the way, let's talk about BPC.
(03:41):
It's a synthetic peptide that's derived from a naturally occurring protein in the human
stomach.
Originally, it was studied for its role in gut health, but it was quickly realized that
this peptide had several other regenerative properties and has been shown to repair muscle
tendon and ligament injuries, enhance gut healing and combat leaky gut, reduce cystic
(04:06):
and systemic inflammation, protect the brain from stress induced damage, and speed up post
recovery after surgery.
Now BPC157 works by stimulating what is called angiogenesis, which is a process that involves
formation of new blood vessels.
More blood flow to damage tissue means faster healing and less pain, something anyone dealing
(04:32):
with injuries or inflammation would surely welcome.
This may be a bit of a rhetorical question, but who cares?
Well, if you're in your 30s, 40s or 50s, you've probably noticed that injuries do not heal
as quickly as they once did.
Maybe you tweaked your shoulder playing a pickup game of basketball, or you've had this
(04:53):
knee pain since you were 20 years old.
Or let's just even say, you're having bloating or fatigue, you're having some gut issues,
you're having some tissue related complications.
While BPC157 addresses these issues at the root cause, unlike other medications that
just mask the symptoms because all they're doing is treating symptoms.
(05:19):
Let's talk a little bit more about how actually BPC does this stuff.
So it's been studied extensively for its role in repairing soft tissue injuries, whether
it's a torn muscle, sprained ligament, or just a nagging tendonitis.
It's been shown to help speed up the recovery and reduce the pain, which then gets us off
(05:42):
of medications like ibuprofen, Tylenol, or even opioids.
Other than just angiogenesis, it also helps to improve nitric oxide modulation, which
causes blood vessel dilation, further improving blood flow to the injured tissues and reducing
inflammation.
(06:03):
And it also increases the expression of growth hormone receptors in what are called tendon
fibromylasts, which aid in the repair of tendons, ligaments, and muscles.
I had a patient that came to me because he had injured his shoulder while weightlifting
at a gym and he had done physical therapy, he had been on anti-inflammatory medications
(06:26):
for several months and he was just not having any progress.
And he contacted me asking about peptides that could potentially help him.
Well, I started him on BPC 157 and three weeks later, he felt significant improvement.
He didn't need to see the orthopedic surgeon.
(06:48):
He was back to baseline.
He was doing the same exercises in the gym and he was actually able to strengthen the
muscles around his shoulder.
And to this day, he's doing fantastic.
While we often hear about the pain reduction and accelerated healing of BPC 157, what we
really need to understand is this medication was originally researched for its ability
(07:13):
to heal ulcers, leaky gut syndrome, and inflammatory bowel disease.
It actually strengthens the gut lining to reduce inflammation and restore balance to
the digestive system.
So if you've had a lot of issues with acid reflux, bloating, or specific food intolerances,
(07:34):
BPC 157 can help restore your gut health naturally and keep you away from medications like proton
pump inhibitors or any kind of long-term medication that absolutely just damages the gut microbiome.
Another amazing benefit of BPC 157 is its mental effects.
(07:56):
Now chronic stress doesn't just wear you down mentally.
It also has physical effects on your brain and nervous system.
And there have been several studies that suggest BPC 157 has a palethora of neuroprotective
benefits that help to reduce stress-induced brain damage, combat anxiety and depression,
(08:17):
and improve overall cognitive function.
This is a huge deal for a lot of individuals who struggle with fatigue or brain fog throughout
the day or those just trying to run a small business or just to get through the day.
Well if BPC 157 is so amazing, then why hasn't it been FDA approved?
(08:41):
Well the answer is simple but also disheartening.
It's money.
So peptides like BPC 157 can't be patented.
They can't be patented in the same way a synthetic drug can.
And pharmaceutical companies do not want to invest in large-scale human trials unless
there's a profit incentive.
(09:02):
A natural compound that helps people recover without dependency on prescription medications
is a threat to their business model.
So instead of getting mainstream attention, BPC remains an underground solution spread
by biohackers, alternative health practitioners and self-experimenters.
(09:25):
And this brings up a huge issue such as manufacturing.
I mean my god, people can make this shit in their bathtub if they wanted to.
There's no rules or regulations on producing this.
And that's where one of the biggest issues with all of these peptides come from is we've
(09:45):
been forced to have to seek these out through anyone who we can source it from.
And because of that, there's a lot of unethical practices in making these.
Now while I will say a lot of the peptides that you get at least over the counter are
safe, they're oftentimes under dosed.
(10:06):
Or they contain just a small fragment of the peptide you think you're getting with a lot
of filler.
And that's because no one's regulating these.
These aren't always made in a strict sterile pharmaceutical setting.
Since it does not have an FDA approval, you've probably seen online in big bold letters for
(10:31):
research purposes only, not for human consumption.
That is one way that companies are still able to get these peptides out.
So how is BPC 157 taken?
Well it depends.
The most common forms are either injectable or oral.
(10:53):
And some of the differences between the two is that with the injectable, you're just using
a very small needle and you're injecting it near the site of pain into the fat tissue.
And some will say that this is better at targeting a specific injury.
For example, you've got tennis elbow, lateral epicondylitis.
(11:16):
You inject the BPC 157 into the outside of your elbow, just the small tissue.
You pinch up a little tissue, you inject it in there, and it will help with all these
amazing benefits.
Now the oral, okay, you don't have to poke yourself, which is great, but it has a better
effect on gut health, on the gut brain axis, because it's going through the stomach.
(11:41):
And it has a more systemic effect on all the little aches and pains in your body.
Now BPC 157 is more stable when taken orally than most other peptides, because remember,
it's derived from gastric juices, proteins found in gastric juices.
But there's also other specific pharmacies, I work with one that can actually, they've
(12:05):
adjusted the oral formulation to be more bioavailable in the stomach.
And I have had several patients compare the injectable version of BPC to the oral version
of BPC and have the exact same effect.
And the other benefit of taking the pill, the oral form, is that it's not just going
(12:26):
to affect your elbow, but it's going to affect that little nagging back pain, right?
The little aches and pains that you have as well.
Because let's be honest, how many of us just have one little injury, right?
If you're like me, it's everywhere, it's widespread.
So the pill is a great option, but you also have to realize, you know, when you inject
(12:51):
it closer to a site of injury, it can have a more localized effect.
Let's talk a little bit about dosing.
So with oral BPC 157, the dose is typically 500 to 1000 micrograms, one to two times daily.
And injections is roughly 250 to 500 micrograms, one to two times daily.
(13:16):
Now oftentimes when you get your injectable BPC 157, you do have to reconstitute it, which
means you're going to get a vial with what's called a lyophilized powder, and you're going
to get some bacteriostatic water.
You're going to need to actually add the water to the peptide.
And that's called reconstitution.
And then from there, you would keep it in the refrigerator and you would inject it.
(13:40):
A lot of people stack multiple peptides and a common stack that I see with BPC 157 is
either TB 500, or I've seen some individuals do CJC 1295 with ipameralin and TB 500.
You can really stack as many of these as you want.
(14:03):
I'd say one of the biggest barriers to that is cost, because the more peptides you use,
the more expensive it's going to be.
So stacking three, four peptides, it could be a little cost prohibitive.
What kind of side effects are we looking at with BPC 157?
Well, there's really none.
(14:24):
Some people have mentioned some mild nausea, temporary dizziness, or if you're doing the
injectable form, a little bit of irritation at the site.
But otherwise, this is an incredibly safe medication and a true crime that the FDA is
not allowing this to be approved and spread to the masses.
(14:46):
Before the podcast, I had a couple patients reach out with just small little testimonials
regarding their effects on BPC.
So I'm just going to read a couple here.
After months of knee pain, I tried BPC 157 and within 10 days, my pain was cut in half.
It's like my body finally started healing itself properly.
(15:08):
I've battled IBS four years and nothing worked long term.
Within two weeks of BPC 157, my bloating and cramping nearly disappeared.
Now those are some amazing testimonials and I see and hear reports like that all the time.
So basically BPC 157 is a naturally derived protein from gastric juices.
(15:34):
And when we supplement with this, we get a plethora of benefits, including accelerated
healing, improved mental cognition, and increased gut health.
Could you ask for more?
We interrupt this program to bring you an important announcement.
Look guys, the harsh reality is that aging naturally is no longer possible.
(15:58):
We're bombarded with endocrine disruptors every day without even knowing it.
Seeking treatment usually leads to the prescription of unnecessary medications and unwanted reassurance
that what we're experiencing is normal, but it's not.
At SteelCity HRT and WeightLoss, we not only ask questions, but listen to answers and believe
(16:21):
that treatment cannot be a cookie cutter protocol.
If you're curious about the amazing benefits of hormone replacement therapy or have been
turned away by our traditional Western medical society, don't hesitate to call 719-669-4223
now to schedule labs and discuss treatment options.
(16:57):
Do women need testosterone supplementation?
Hell yes they do.
A common misconception is that women do not need testosterone supplementation, but what
we're neglecting to think about is testosterone is the most abundant hormone in a woman's
body.
A woman has about 10 times more testosterone than estrogen.
(17:23):
So why in the world would we not replace it?
I will say that estradiol is the best bang for your buck for a female because of the
amazing health benefits, but out of all the women I treat, 99% of them report an improvement
(17:43):
in their symptoms with the testosterone almost immediately.
The estradiol takes some time and it does help with a lot of symptoms, but that testosterone
is a quick acting medication for most of the women and it's one of the ones that actually
helps to preserve muscle mass, improve bone density, and help with fat loss.
(18:06):
Who doesn't want that?
So why would we not treat women?
And I'm not exaggerating this, I have had providers who've reached out to me and say,
why would you put a woman on testosterone?
You can do just estradiol and progesterone.
Absolutely not.
That's completely unfair.
(18:27):
I would never neglect a woman of additional testosterone supplementation unless there
was an issue such as PCOS or there was a concern of already having too much.
That would be a joint decision making process, but absolutely please give the women testosterone.
(18:48):
Should guys supplement with estradiol?
What a loaded question this one is.
I will say that it's still very taboo, but I say yes, I absolutely advocate for supplementing
estradiol in men who are on testosterone replacement therapy.
And the reason I say this is because what I have found is that everyone has a genetically
(19:14):
set testosterone to estradiol ratio.
And frankly, it seems to be fairly wide, meaning that you can close that gap a little bit.
And some of the benefits of estradiol include protecting your bones, protecting your heart.
But for us guys, it helps with libido.
It improves your sexual arousal, but it also helps with erections guys, harder erections.
(19:41):
Who doesn't want that?
And so is it for everyone?
It's not, it's absolutely not.
But I will say personally, I take a milligram of estradiol every other day and I love it.
I feel great.
I do feel like it calms me down a little bit.
I do feel like I sleep better.
Of course, harder erections, probably too much information there.
(20:03):
But then also the things I can't see, the protection of bones and heart.
So I do think that I'd say 90% of men could benefit from supplementation of estradiol
with their TRT regimen.
That's huge.
Because if you're not on TRT and you're supplementing with estradiol, we could probably close that
(20:24):
gap too much, make it too narrow.
And then we can start to develop some estrogenic symptoms.
How much progesterone is too much?
Well, I don't think that number exists.
Now the only natural physical state that a human goes into where their progesterone level
(20:47):
is off the charts is during pregnancy because it's being made by the placenta.
When you ask a woman at what point in your life did you just feel the best, most women
will say when I was pregnant.
And that's because progesterone, it upregulates GABA receptors in the brain, which are responsible
(21:07):
for calming, relaxing sensations, just overall feelings of wellbeing.
It's actually one of the downstream derivatives of progesterone, allopregnanolone is called
the valium of the brain for a reason guys.
And so I have a lot of women say, you know, Hey, my practitioner put me on 50 milligrams
(21:29):
of progesterone and I'm not noticing any effect.
Is it not enough?
Is it too much?
And you know, really it just depends.
I usually start my women, now caveat, this is not medical advice.
This is just what I do in my practice.
I start most of my women off at 200 milligrams every night.
(21:49):
Okay.
I want to say every other night because we have that discussion, but I have zero women
on every other night progesterone.
All the women I treat are on every night at this point.
So 200 milligrams every night.
I have some that slowly creeped their way up to 400.
They're still fine.
There's no danger.
(22:10):
There's no number that we're going to get to that's going to cause imminent harm or
death.
One thing you do need to consider is as that progesterone level increases, it down regulates
your estradiol receptors.
So we may need to increase your estradiol levels.
And I've seen that on a handful of occasions where we slowly creep up our progesterone
(22:34):
and we're not taking enough estradiol.
So we'll actually drive our estradiol levels down, which that can correlate to some harm,
especially when we're trying to prevent osteoporosis and Alzheimer's dementia, neurocognitive disorders.
So I will say that the one caveat to continuing to increase your progesterone is you really
(22:56):
do want to watch your estradiol levels because you will drive them down the higher you go.
But otherwise there is no maximum limit of progesterone.
A lot of women will use it based off of headaches or anxiety.
They'll dose it as needed.
I typically say, you know what, if you have frequent insomnia, I say just take it every
(23:18):
night to help you with sleep.
If you're the kind of person that can take it as needed and be okay when you're not taking
it.
Sure.
Do that as well.
To each their own.
This has to be individualized guys.
There is no clear cut answer.
I want to thank everyone for listening to today's episode of the Hormones Happen podcast
(23:41):
and hope that you were able to find some value in the information that was provided today.
If you have any questions that you would like to have discussed on the podcast, please send
them to the email listed below or message us on the Still City HRT and Weight Loss Facebook
page.
Remember you are not alone in the war on hormones.
Stay optimized.
And this brings up a huge issue, such as manufacturing.
(00:09):
I mean, my God, people can make this shit in their bathtub if they wanted to.
Welcome to the Hormones Happen podcast, a podcast designed for individuals like you
(00:33):
who are curious about the amazing benefits of hormone replacement therapy.
I'm your host, Jeremiah, and I'm a nurse practitioner who specializes in HRT.
I've seen firsthand the debilitating effects of hormone deficiency and have personally experienced
the benefits of optimization.
My goal is to arm you with information regarding the good, the bad, and even taboo aspects
(00:56):
of HRT while answering your burning questions.
Please join me for today's episode of the Hormones Happen podcast.
(01:19):
What's going on, guys?
Welcome back to another episode of Hormones Happen.
Now, what if I told you there was a natural compound capable of accelerating wound healing,
reducing chronic pain, restoring gut health, and even protecting your brain from stress
and anxiety?
(01:40):
Imagine this compound has been around for decades, studied in labs worldwide, and yet
you've never likely heard of it.
Well, maybe you have.
If you're privy to social media, you've probably heard of this peptide called the Wolverine
peptide.
Now, what I'm talking about is the compound BPC157, a regenerative peptide that could
(02:07):
be a game changer for many men and women that are looking for help with slow recovery, nagging
injuries, digestive issues, or unexplained fatigue, BPC157 might be the secret weapon.
But the kicker is Big Pharma doesn't want you to know about it.
(02:31):
And why is that?
Because if peptides like BPC157 became mainstream, they could replace expensive prescription
drugs for pain.
That's billions of dollars in lost revenue for pharmaceutical companies.
So instead of marketing this natural compound, they keep it tucked away.
(02:51):
But let's shine some light on it.
And let's talk about how this peptide is changing the world of injuries.
So before we specifically talk about BPC157, let's take a step back and talk about what
is a peptide.
So a peptide is a single linear chain of amino acids, and when this chain is less than 50
(03:17):
amino acids in length, we call it a peptide.
When it's greater than 50, we call it a polypeptide.
And several polypeptides linked together is called a protein.
Now fun fact, BPC157 is composed of 15 amino acids.
So now that we got that out of the way, let's talk about BPC.
(03:41):
It's a synthetic peptide that's derived from a naturally occurring protein in the human
stomach.
Originally, it was studied for its role in gut health, but it was quickly realized that
this peptide had several other regenerative properties and has been shown to repair muscle
tendon and ligament injuries, enhance gut healing and combat leaky gut, reduce cystic
(04:06):
and systemic inflammation, protect the brain from stress induced damage, and speed up post
recovery after surgery.
Now BPC157 works by stimulating what is called angiogenesis, which is a process that involves
formation of new blood vessels.
More blood flow to damage tissue means faster healing and less pain, something anyone dealing
(04:32):
with injuries or inflammation would surely welcome.
This may be a bit of a rhetorical question, but who cares?
Well, if you're in your 30s, 40s or 50s, you've probably noticed that injuries do not heal
as quickly as they once did.
Maybe you tweaked your shoulder playing a pickup game of basketball, or you've had this
(04:53):
knee pain since you were 20 years old.
Or let's just even say, you're having bloating or fatigue, you're having some gut issues,
you're having some tissue related complications.
While BPC157 addresses these issues at the root cause, unlike other medications that
just mask the symptoms because all they're doing is treating symptoms.
(05:19):
Let's talk a little bit more about how actually BPC does this stuff.
So it's been studied extensively for its role in repairing soft tissue injuries, whether
it's a torn muscle, sprained ligament, or just a nagging tendonitis.
It's been shown to help speed up the recovery and reduce the pain, which then gets us off
(05:42):
of medications like ibuprofen, Tylenol, or even opioids.
Other than just angiogenesis, it also helps to improve nitric oxide modulation, which
causes blood vessel dilation, further improving blood flow to the injured tissues and reducing
inflammation.
(06:03):
And it also increases the expression of growth hormone receptors in what are called tendon
fibromylasts, which aid in the repair of tendons, ligaments, and muscles.
I had a patient that came to me because he had injured his shoulder while weightlifting
at a gym and he had done physical therapy, he had been on anti-inflammatory medications
(06:26):
for several months and he was just not having any progress.
And he contacted me asking about peptides that could potentially help him.
Well, I started him on BPC 157 and three weeks later, he felt significant improvement.
He didn't need to see the orthopedic surgeon.
(06:48):
He was back to baseline.
He was doing the same exercises in the gym and he was actually able to strengthen the
muscles around his shoulder.
And to this day, he's doing fantastic.
While we often hear about the pain reduction and accelerated healing of BPC 157, what we
really need to understand is this medication was originally researched for its ability
(07:13):
to heal ulcers, leaky gut syndrome, and inflammatory bowel disease.
It actually strengthens the gut lining to reduce inflammation and restore balance to
the digestive system.
So if you've had a lot of issues with acid reflux, bloating, or specific food intolerances,
(07:34):
BPC 157 can help restore your gut health naturally and keep you away from medications like proton
pump inhibitors or any kind of long-term medication that absolutely just damages the gut microbiome.
Another amazing benefit of BPC 157 is its mental effects.
(07:56):
Now chronic stress doesn't just wear you down mentally.
It also has physical effects on your brain and nervous system.
And there have been several studies that suggest BPC 157 has a palethora of neuroprotective
benefits that help to reduce stress-induced brain damage, combat anxiety and depression,
(08:17):
and improve overall cognitive function.
This is a huge deal for a lot of individuals who struggle with fatigue or brain fog throughout
the day or those just trying to run a small business or just to get through the day.
Well if BPC 157 is so amazing, then why hasn't it been FDA approved?
(08:41):
Well the answer is simple but also disheartening.
It's money.
So peptides like BPC 157 can't be patented.
They can't be patented in the same way a synthetic drug can.
And pharmaceutical companies do not want to invest in large-scale human trials unless
there's a profit incentive.
(09:02):
A natural compound that helps people recover without dependency on prescription medications
is a threat to their business model.
So instead of getting mainstream attention, BPC remains an underground solution spread
by biohackers, alternative health practitioners and self-experimenters.
(09:25):
And this brings up a huge issue such as manufacturing.
I mean my god, people can make this shit in their bathtub if they wanted to.
There's no rules or regulations on producing this.
And that's where one of the biggest issues with all of these peptides come from is we've
(09:45):
been forced to have to seek these out through anyone who we can source it from.
And because of that, there's a lot of unethical practices in making these.
Now while I will say a lot of the peptides that you get at least over the counter are
safe, they're oftentimes under dosed.
(10:06):
Or they contain just a small fragment of the peptide you think you're getting with a lot
of filler.
And that's because no one's regulating these.
These aren't always made in a strict sterile pharmaceutical setting.
Since it does not have an FDA approval, you've probably seen online in big bold letters for
(10:31):
research purposes only, not for human consumption.
That is one way that companies are still able to get these peptides out.
So how is BPC 157 taken?
Well it depends.
The most common forms are either injectable or oral.
(10:53):
And some of the differences between the two is that with the injectable, you're just using
a very small needle and you're injecting it near the site of pain into the fat tissue.
And some will say that this is better at targeting a specific injury.
For example, you've got tennis elbow, lateral epicondylitis.
(11:16):
You inject the BPC 157 into the outside of your elbow, just the small tissue.
You pinch up a little tissue, you inject it in there, and it will help with all these
amazing benefits.
Now the oral, okay, you don't have to poke yourself, which is great, but it has a better
effect on gut health, on the gut brain axis, because it's going through the stomach.
(11:41):
And it has a more systemic effect on all the little aches and pains in your body.
Now BPC 157 is more stable when taken orally than most other peptides, because remember,
it's derived from gastric juices, proteins found in gastric juices.
But there's also other specific pharmacies, I work with one that can actually, they've
(12:05):
adjusted the oral formulation to be more bioavailable in the stomach.
And I have had several patients compare the injectable version of BPC to the oral version
of BPC and have the exact same effect.
And the other benefit of taking the pill, the oral form, is that it's not just going
(12:26):
to affect your elbow, but it's going to affect that little nagging back pain, right?
The little aches and pains that you have as well.
Because let's be honest, how many of us just have one little injury, right?
If you're like me, it's everywhere, it's widespread.
So the pill is a great option, but you also have to realize, you know, when you inject
(12:51):
it closer to a site of injury, it can have a more localized effect.
Let's talk a little bit about dosing.
So with oral BPC 157, the dose is typically 500 to 1000 micrograms, one to two times daily.
And injections is roughly 250 to 500 micrograms, one to two times daily.
(13:16):
Now oftentimes when you get your injectable BPC 157, you do have to reconstitute it, which
means you're going to get a vial with what's called a lyophilized powder, and you're going
to get some bacteriostatic water.
You're going to need to actually add the water to the peptide.
And that's called reconstitution.
And then from there, you would keep it in the refrigerator and you would inject it.
(13:40):
A lot of people stack multiple peptides and a common stack that I see with BPC 157 is
either TB 500, or I've seen some individuals do CJC 1295 with ipameralin and TB 500.
You can really stack as many of these as you want.
(14:03):
I'd say one of the biggest barriers to that is cost, because the more peptides you use,
the more expensive it's going to be.
So stacking three, four peptides, it could be a little cost prohibitive.
What kind of side effects are we looking at with BPC 157?
Well, there's really none.
(14:24):
Some people have mentioned some mild nausea, temporary dizziness, or if you're doing the
injectable form, a little bit of irritation at the site.
But otherwise, this is an incredibly safe medication and a true crime that the FDA is
not allowing this to be approved and spread to the masses.
(14:46):
Before the podcast, I had a couple patients reach out with just small little testimonials
regarding their effects on BPC.
So I'm just going to read a couple here.
After months of knee pain, I tried BPC 157 and within 10 days, my pain was cut in half.
It's like my body finally started healing itself properly.
(15:08):
I've battled IBS four years and nothing worked long term.
Within two weeks of BPC 157, my bloating and cramping nearly disappeared.
Now those are some amazing testimonials and I see and hear reports like that all the time.
So basically BPC 157 is a naturally derived protein from gastric juices.
(15:34):
And when we supplement with this, we get a plethora of benefits, including accelerated
healing, improved mental cognition, and increased gut health.
Could you ask for more?
We interrupt this program to bring you an important announcement.
Look guys, the harsh reality is that aging naturally is no longer possible.
(15:58):
We're bombarded with endocrine disruptors every day without even knowing it.
Seeking treatment usually leads to the prescription of unnecessary medications and unwanted reassurance
that what we're experiencing is normal, but it's not.
At SteelCity HRT and WeightLoss, we not only ask questions, but listen to answers and believe
(16:21):
that treatment cannot be a cookie cutter protocol.
If you're curious about the amazing benefits of hormone replacement therapy or have been
turned away by our traditional Western medical society, don't hesitate to call 719-669-4223
now to schedule labs and discuss treatment options.
(16:57):
Do women need testosterone supplementation?
Hell yes they do.
A common misconception is that women do not need testosterone supplementation, but what
we're neglecting to think about is testosterone is the most abundant hormone in a woman's
body.
A woman has about 10 times more testosterone than estrogen.
(17:23):
So why in the world would we not replace it?
I will say that estradiol is the best bang for your buck for a female because of the
amazing health benefits, but out of all the women I treat, 99% of them report an improvement
(17:43):
in their symptoms with the testosterone almost immediately.
The estradiol takes some time and it does help with a lot of symptoms, but that testosterone
is a quick acting medication for most of the women and it's one of the ones that actually
helps to preserve muscle mass, improve bone density, and help with fat loss.
(18:06):
Who doesn't want that?
So why would we not treat women?
And I'm not exaggerating this, I have had providers who've reached out to me and say,
why would you put a woman on testosterone?
You can do just estradiol and progesterone.
Absolutely not.
That's completely unfair.
(18:27):
I would never neglect a woman of additional testosterone supplementation unless there
was an issue such as PCOS or there was a concern of already having too much.
That would be a joint decision making process, but absolutely please give the women testosterone.
(18:48):
Should guys supplement with estradiol?
What a loaded question this one is.
I will say that it's still very taboo, but I say yes, I absolutely advocate for supplementing
estradiol in men who are on testosterone replacement therapy.
And the reason I say this is because what I have found is that everyone has a genetically
(19:14):
set testosterone to estradiol ratio.
And frankly, it seems to be fairly wide, meaning that you can close that gap a little bit.
And some of the benefits of estradiol include protecting your bones, protecting your heart.
But for us guys, it helps with libido.
It improves your sexual arousal, but it also helps with erections guys, harder erections.
(19:41):
Who doesn't want that?
And so is it for everyone?
It's not, it's absolutely not.
But I will say personally, I take a milligram of estradiol every other day and I love it.
I feel great.
I do feel like it calms me down a little bit.
I do feel like I sleep better.
Of course, harder erections, probably too much information there.
(20:03):
But then also the things I can't see, the protection of bones and heart.
So I do think that I'd say 90% of men could benefit from supplementation of estradiol
with their TRT regimen.
That's huge.
Because if you're not on TRT and you're supplementing with estradiol, we could probably close that
(20:24):
gap too much, make it too narrow.
And then we can start to develop some estrogenic symptoms.
How much progesterone is too much?
Well, I don't think that number exists.
Now the only natural physical state that a human goes into where their progesterone level
(20:47):
is off the charts is during pregnancy because it's being made by the placenta.
When you ask a woman at what point in your life did you just feel the best, most women
will say when I was pregnant.
And that's because progesterone, it upregulates GABA receptors in the brain, which are responsible
(21:07):
for calming, relaxing sensations, just overall feelings of wellbeing.
It's actually one of the downstream derivatives of progesterone, allopregnanolone is called
the valium of the brain for a reason guys.
And so I have a lot of women say, you know, Hey, my practitioner put me on 50 milligrams
(21:29):
of progesterone and I'm not noticing any effect.
Is it not enough?
Is it too much?
And you know, really it just depends.
I usually start my women, now caveat, this is not medical advice.
This is just what I do in my practice.
I start most of my women off at 200 milligrams every night.
(21:49):
Okay.
I want to say every other night because we have that discussion, but I have zero women
on every other night progesterone.
All the women I treat are on every night at this point.
So 200 milligrams every night.
I have some that slowly creeped their way up to 400.
They're still fine.
There's no danger.
(22:10):
There's no number that we're going to get to that's going to cause imminent harm or
death.
One thing you do need to consider is as that progesterone level increases, it down regulates
your estradiol receptors.
So we may need to increase your estradiol levels.
And I've seen that on a handful of occasions where we slowly creep up our progesterone
(22:34):
and we're not taking enough estradiol.
So we'll actually drive our estradiol levels down, which that can correlate to some harm,
especially when we're trying to prevent osteoporosis and Alzheimer's dementia, neurocognitive disorders.
So I will say that the one caveat to continuing to increase your progesterone is you really
(22:56):
do want to watch your estradiol levels because you will drive them down the higher you go.
But otherwise there is no maximum limit of progesterone.
A lot of women will use it based off of headaches or anxiety.
They'll dose it as needed.
I typically say, you know what, if you have frequent insomnia, I say just take it every
(23:18):
night to help you with sleep.
If you're the kind of person that can take it as needed and be okay when you're not taking
it.
Sure.
Do that as well.
To each their own.
This has to be individualized guys.
There is no clear cut answer.
I want to thank everyone for listening to today's episode of the Hormones Happen podcast
(23:41):
and hope that you were able to find some value in the information that was provided today.
If you have any questions that you would like to have discussed on the podcast, please send
them to the email listed below or message us on the Still City HRT and Weight Loss Facebook
page.
Remember you are not alone in the war on hormones.
Stay optimized.
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