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October 24, 2025 18 mins

If you’re curious or concerned about the safety, effectiveness, or reputation of compounding pharmacies, this episode is packed with information you won’t want to miss.

Welcome back to Weight Loss Decoded – GLP Edition! I'm your host, Sharon Polsky, your go-to GLP Fact Fairy. In today’s episode, we’re tackling one of the hottest—and most controversial—topics in weight management: compounding pharmacies. To give us the inside scoop, I chat with Matt Montes, Chief Clinical Officer at Strive Pharmacy. Together, we unpack the myths, truths, and realities behind compounding pharmacies, especially when it comes to GLP-1 weight loss medications.

Matt shares his journey into the world of personalized medicine, explains how compounding pharmacies are actually highly regulated, and reveals the rigorous testing and transparency practices that set Strive apart. We talk about patient experiences, how compounding allows for flexible dosing (hello, microdosing GLP-1s!), and why finding your medication sweet spot can be a game changer—whether you’re managing weight, thyroid issues, or more.

We decode the good, the bad, and the ugly—and set the record straight on a new era in weight management!

Moments

00:00 "Compounding Pharmacies: The Truth"

03:54 Origins and Role of Compounding Pharmacies

07:13 Strict Medication Testing Standards

12:33 Finding the Thyroid Medication Sweet Spot

13:40 Microdosing GLP1s for Weight Control

17:08 "Tracking Medication Safety Process"

Here are 3 key takeaways for anyone curious about compounding pharmacies and GLP-1 therapy:

  • Compounding Is Highly Regulated: Matt shared that compounding pharmacies like Strive must meet strict standards from state boards, USP requirements, and FDA guidelines—often exceeding these minimums for patient safety.
  • Transparency Is Essential: Before choosing any compounding pharmacy, always ask for documentation. You deserve to see proof of potency, safety, and efficacy—from raw ingredients to the finished medication batch.
  • Personalization Is a Game Changer: With compounding, patients can fine-tune their doses (like GLP-1 or thyroid meds) in ways big manufacturers simply can’t—leading to fewer side effects and better outcomes.

Think of our podcast as your personal weight loss toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support.

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https://uppbeat.io/t/matrika/when-we-were-young

License code: 3VR556DKJQFEFZSU

Copyright 2025 Sharon Polsky

The Weight Loss Decoded - GLP Edition Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health...

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