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June 1, 2024 9 mins
DR. ALFRED O. BONATI DISCUSSES THE LATEST ADVANCEMENTS ON SPINAL CORD INJURY TREATMENT.    
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(00:00):
You're listening to American Medicine Today,presented by the Benadi Spine Institute, featuring
internationally acclaimed inventor of the Beannati spineprocedures, Alfred Benati, MD. Once
again, your host Kimberly Burmel Benatiand co host Ethan Yuger. Welcome to
American Medicine Today. I'm alongside doctorBernardi talking about the advancements in spinal cord

(00:22):
injuries. What is new on mathorizon. Well, for years we are
postle with the results, the advancesand the enormous amount of damage that an
individual who suffered a spinal cord injuryneeds to support and live with. And

(00:49):
we don't have any answers to that. But there are some studies that that
were known recently in Japan. Theywere working with insects and they capitate the
insect and they found that there wassomething very curious this insect that they didn't
have brain. They still can walkand avoid obstacles that they were on their

(01:11):
path. That was totally crazy atthat time, and then they start to
investigate further and they would realize thatthere are other centers that they can't perform
without the brain, and they discover. They move from the insects to bigger

(01:32):
animals just to be able to beable to dissect the nervous system and understand
if something different, why the systemwork in the insects. And they took
a couple of rats, one asthe rat that will be the project in
the other one somebody in another ratthat will be the normal rut. Well,

(01:57):
they decided that what type of reactionis the one and where that reaction
happened on the insects, and thenthey destroyed the brain on the rat and
then the rat got paralyzed. Sothen what they did is the legs of
the rat was dangling, and theyput a wire very close to the end

(02:24):
of that leg and then they pushedslowly the leg towards the wire and the
wire had electricity. When that happens, the electrical shock to the leg.
Immediately the rat moved the leg andhold it up. And what's the leg?

(02:45):
What's the rat without brain? Sothe question was who is creating this
reaction and how this reaction can beapplied to humans? Correct. Well,
what they did is they look atthe nervous system and then they study the

(03:07):
cord and the cells that they wereon the top of the cord, they
were able to create that reaction.If you put the leg close to the
wire, the rat will move theleg out from touching the wire because it

(03:30):
was a shocking type of a discomfort. So the discomfort make the spanel cord
cells to do that motion. Butwhat was amazing is that the leg in
ten minutes, the spanel coll learnthat the legs shouldn't go down because you're

(03:52):
going to be shocked again, sothe legs remain up the wire. And
when they froyd these cells, theleg was able to touch the wire and
don't get the don't get the legup either. So those cells are neurons

(04:14):
that they kempt on the upper partof the spanel cord. But they discovered
another group of cells on the lowerpart of the spinel cord, and those
cells on the lower part of thespane cord seems to be that they are
the ones that they allowed these othercells to maintain the knowledge. So one

(04:36):
was to create motion, the otherone was to create knowledge of that action.
So what happened then was any timethat they touched the wire, the
lage went up. Then the nextday they brought the rat again and they
put it in the same situation.They tried to put it around the wire

(04:59):
and and the leg immediately didn't letthe scientists to do that. They start
to fight it. And why didthat because knowledge that's going to be shocked.
So now we have one set ofcells that they produce the motion and
one set of cells that they havethe knowledge what you need to do and
what you do and what you cannotdo or what you shouldn't do. That

(05:23):
type of information today is probably anincredible information to educate paralyze people because if
we can use the cells and thosecells on the top are going to create
the type of reaction, they canwalk, but at the same time they

(05:45):
can recognize the motion, avoid objectsthat they are underway, and at the
same time, the next day theyknow that they can walk. So now
with the knowledge they can walk,they can perform some some type of ambulation.
I don't know how good it is, I don't know how exact it

(06:08):
is, but they can move.That advance is an incredible advance on a
spine surgery today. So are yousaying that it's both voluntary and involuntary at
that point, Well, it isvoluntary by the time that you have knowledge
that when you put your leg downthere in the electrical shock, you don't

(06:30):
want to be shocked again. Youcan you maintain the leg up. That's
that's knowledge that you shouldn't put yourleg down there. That's voluntary, and
it's voluntary. Also the fact thatyou can move the leg when you need
to do something. Like the insects, they can walk and they can walk
to escaping the area of danger orwhatever it is, but they don't have

(06:53):
a brain. They are the capitating. Okay, so this is this is
these advances are I mean, Iam so envy of the young individuals that
they are going to medicine today becausethe advances that you are going to see
and the tremendous amount of information thatis coming from the genome. This is

(07:19):
also a situation that's associated with agene. Is a gene that manipulate these
cells, the top cells and thelower cells. And if you move that
gene or remove that gene, thenthese things are not they don't really happen.

(07:40):
So when you remove the gene,you see that the leg is dangling
and it is being shocked and doesn'tmove, and the next day you try
to check it again. And stilldoesn't move, so doesn't learn anything and
doesn't move either. I wonder howfar away we are from paralyzed human trials

(08:01):
to see how this may work.Well, that's years, because everything is
at the level of the genes yet. And although the genetics are going absolutely
crazy and I am so I gototally in awe when I see the things
that the genes can do, andthe genes the information that we have is

(08:26):
more and more, and how theycan change in how they can move,
and how we can remove illnesses thatthey are bad illnesses today like blood this
gracious and things like that that youjust remove the gene and the next generation
doesn't have the problem. So allthese things are going to be in the

(08:46):
next fifty years. Something is goingto be a routine. But the important
thing for this, for example,in this factor that we're talking before,
for demyelin, well, if youcan reconstruct the milin, you practically are
giving to the human and expansion inlife that God knows how long can be.

(09:11):
If the only difference on here isthat if the miline recontracts your nervous
system and you can think better andit's not damaging your brain and brain not
damaging your muscles, and you respondfast and all these things. I'm telling
you you are twenty years old.Well, we will certainly keep a watchful

(09:35):
eye on the innovations in that medicaltechnology. Thank you for sharing about the
advancements of spinal cord injuries and whatmay be on the horizon. Make sure
you stay tuned. We'll have moreafter the break. You're listening to American
Medicine Today.
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