Focus on Women's and Men's Health

HPV Vaccine: A Systematic Review of 10 Years of Real-World Experience

October 10, 20164 min
Host: Susan J. Wysocki, WHNP, FAANP

Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience Clinical Infectious Disease 16 Aug 15;63(4):519-27. doi: 10.1093/cid/ciw354. Epub 2016 May 26. Garland SM1, Kjaer SK2, Muñoz N3, Block SL4, Brown DR5, DiNubile MJ6, Lindsay BR6, Kuter BJ6, Perez G7, Dominiak-Felden G8, Saah AJ6,Drury R8, Das R6, Velicer C6. Abstract: Prophylactic human papillomavirus (HPV) vaccination programs constitute major public health initiatives worldwide. We assessed the global effect of quadrivalent HPV (4vHPV) vaccination on HPV infection and disease. PubMed and Embase were systematically searched for peer-reviewed articles from January 2007 through February 2016 to identify observational studies reporting the impact or effectiveness of 4vHPV vaccination on infection, anogenital warts, and cervical cancer or precancerous lesions. Over the last decade, the impact of HPV vaccination in rea

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