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September 23, 2025 92 mins

Matias interviews Rob Malenka.

In this episode, we discuss:

  • Why progress in psychiatry is slow because the brain is the most complex organ and many disorders are highly heterogeneous
  • The bottlenecks including weak replicability in research, academic politics, perverse incentives, and pharma’s avoidance of neuropsychiatry
  • How breakthroughs require early detection, rigorous science, and bridging academia with biotech through venture philanthropy
  • How success depends on mission-driven, ethical people who align science, capital, and patient impact.
  • The opportunities in neuromodulation, data-driven precision medicine, and combination therapies.

Credits:

Created by Greg Kubin and Matias Serebrinsky
Host: Matias Serebrinsky
Produced by Caitlin Ner & Nico V. Rey 

Find us at businesstrip.fm and psymed.ventures
Follow us on Instagram and Twitter!
Theme music by Dorian Love
Additional Music: Distant Daze by Zack Frank

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