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May 14, 2026 57 mins

EEShow (Everything’s Energy Show)

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Learn more at https://www.eesystem.com/ Ever wonder about that euphoric feeling during stress? It's often your body's anti-inflammatory response to the stress hormone, high cortisol. This sensation can make you feel clear, but it's actually your fight or flight response kicking in, even without immediate panic. Understanding this crucial cortisol control is key to managing your body's reactions to chronic stress and perceived scarcity. We sit down with Dan Holtz to examine his thoughts and dive deeper into this topic.

Chapters

  • (00:00) - - Cortisol, stress, and thyroid function
  • (03:00) - - Hormone optimization obsession
  • (06:38) - - Hormones: Clearing confusion, improving life
  • (10:00) - - Hormone testing and SHBG
  • (13:35) - - Progesterone deficiency and women's health
  • (20:21) - - Thyroid, fasting, and hormone balance
  • (27:44) - - Fasting's stress response and thyroid
  • (30:53) - - Adrenal fatigue and energy optimization
  • (37:49) - - Peptides: Cellular communication and longevity
  • (44:15) - - Hormone programs and careful usage

People

Creators & Guests
  • Dan Holtz - Guest
  • Roland - Writer

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The Energy Enhancement System™ (EESystem™) and the content provided on EEShow (Everything’s Energy Show) — including audio, transcripts, and guest comments — are not medical advice. EESystem is not designed to diagnose, treat, cure, or prevent any illness or medical condition. The information presented is for educational and wellness purposes only. If you have or suspect any medical condition, please consult a qualified healthcare professional.

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Episode Transcript

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Roland (00:00):
Cortisol has a euphoric feeling in the body because

(00:02):
there's an anti inflammatoryeffect of cortisol. There's also
euphoric feeling to block painand stress. Sure. Makes you feel
that way. And people say, oh, Ifeel great.
I'm clear. It's because yourbody's under stress. That
clarity is actually you being infight or flight but there's no
panic that's actually in frontof you but your physiology

(00:22):
believes there is becausethere's a food scarcity. From a
thyroid perspective, if youchronically trash your thyroid,
then the body gets into thepatterns of those things. And
that is the one button that getspressed that creates a cascade
of all other things becausewithout thyroid function, there
is no energy.
Welcome back to the Everything'sEnergy Show. I am your host

(00:44):
Roland, and today we have ourfirst repeat guest. He was so
good the first time we had tobring him back because we didn't
really get to see all sides ofhis depth of knowledge. He is
not only the owner of a 48 unitsystem which is Regenerative
Health Center or system

Dan Holtz (01:00):
System.

Roland (01:01):
But Dan Holtz, the man himself who's also an expert in
all things antiaging, longevitymedicine. We're gonna go into a
deep dive in what I think is areally important topic because
it's a confusing topic with alot of nuance but more and more
people are actually wanting toget into it nowadays so I
thought what better thing to dothan ask the man himself to help
us understand how to see throughthe weeds in this industry. Dan,

(01:22):
thank you for being here. Howare doing?

Dan Holtz (01:24):
Thanks for having me, Roland. Doing great. Great
Friday and, looking for a greatweekend.

Roland (01:29):
Absolutely. Yeah. Life is good. I love it.

Dan Holtz (01:31):
Life is good.

Roland (01:32):
So antiaging medicine longevity stuff. This is kind of
your world. How did you get intothis stuff?

Dan Holtz (01:38):
Well, I had a it wasn't great. You know, I have
one of those stories. A tragedybecame a solution. Right? So
often in life you see that wheresomething really terrible
happens and it changes yourwhole life in a very positive
direction.
I'm one of those stories. Wastwenty five years ago I was a

(02:01):
general contractor building highend residential stuff in Malibu,
Pacific Palisades, you know, inthe LA area and had a booming
business, was doing very, verywell. I was racing cars and just
kind of living the dream. But Ijust didn't feel great. I had a
lot of aches and pains.

(02:21):
And I was exhausted all thetime. And I just was really
missing something I just I knewI make a lot of money I should
have been, you know, everythingshould have been perfect, right?
Business booming, everything wassupposedly going great. But why
all these aches and pains andexhaustion and everything? And I

(02:41):
just kept pushing harder andharder and harder.
Well, I got in a really badcrash at a I went in Phoenix
International Raceway and tookthem forty five minutes with the
jaws of life to cut me out ofthe car and they airlifted me
in. I was in a coma, went in thehospital. About a half a day
later, I came out of the coma,and the first thought I had is I

(03:04):
wish I had died. I just I wasdone. I was exhausted.
I I just felt like I can't Ican't keep going this way. I
just wasn't enjoying my lifeanymore because I didn't feel
good. And I thought, you know, Imissed everything here. I just
really gotta figure out what'sgoing on with my health. I mean,

(03:26):
I don't I just can't live thisway anymore.
So it changed my whole life interms my focus became I started
thinking, I just need to justback off on all the business
stuff and and I need to focus onfinding the old Dan Holtz, the
guy that woke up every day withpassion and zest for life and I

(03:47):
gotta go find that guy again.Started doing a bunch of blood
tests, found out that I had nohormones, right? My hormones
were so depleted, it wasamazing. And of course, twenty
five years ago, nobody knewanything about hormones. So
doctors didn't know what to tellme.
They said, well, you know, wedon't really know why your
hormones are low. And I starteddoing some homework, found out

(04:11):
about a guy in Europe who was avery knowledgeable hormone
expert. I started gettinginformation from him and
basically his guidance was thatthis was treatable stuff. In
Europe they treated it all thetime, it was age related hormone
decline, right? I was close to40 years old and it was just

(04:32):
part of aging.
So I quickly set out to learnanything and everything I could
about hormones and how tooptimize hormones. I became, I
started feeling so much betterso fast that I just became in
three weeks of treating hormonedeficiencies, I felt so much

(04:53):
better that I thought I gottafigure out anything and
everything there is to knowabout this because I became
obsessed with feeling greatagain. And I'd done so much in
three weeks, I thought, what'spossible here? And that's that's
how I started on this journeyand and I spent the last twenty
five years working in thisfield. I owned a company called
Beverly Hills RejuvenationCenter, co founded that company

(05:16):
with my partner Devin Hayman andand we just really were obsessed
with wellness and hormoneoptimization.
And we even did aesthetictreatments there to make people
look younger too. If there'sanything anti aging, you know,
we became so excited about itand that's why we went down that
road.

Roland (05:36):
Very interesting. That's it's it's always amazing when
someone tells you a story ofwhat seems like pure tragedy.
Yeah. Isn't there almost, like,the opportunity of equal
magnitude that comes out ofsomething so

Dan Holtz (05:49):
potentially so True. It's always that way. Mhmm.
That's why you gotta just knowthat that will lead you to
another whole level of elevationof life. So it absolutely is.
If you could just hang in thereand just know this is not what
it appears to be, and it's sotrue.

Roland (06:12):
Hindsight is always twenty twenty, though. Right? It
is. If you knew it ahead oftime, it would be boring. So

Dan Holtz (06:17):
And I must admit, even today, knowing all that,
once in a while, some of thechallenges that come and I find
myself going, what's going onhere? Resisting it. Yeah. And
then I just gotta let go and goback gratitude, look back over
my shoulder and realize that,you know, just give it a chance,

(06:37):
something great's gonna come.Everything happens for you, not
to you.
Right?

Roland (06:41):
100% agree. And and look what it's given you this this
arsenal of knowledge now. And Ithink hormones are probably the
best starting point becauseeveryone knows the word hormone.
Yeah. Not many people know thenuances of hormones like there's
peptide hormones, there'ssteroid hormones but I think
people give the word a negativeconnotation in their mind before

(07:02):
a positive connotation.
How would you clear up the theconnotation and the confusion
around hormones so people lookat it with a more open mind?

Dan Holtz (07:11):
Well, you know, when I started twenty five years ago,
when you would say the this isgonna sound shocking, but just
the word testosterone, very fewpeople could say it.

Roland (07:22):
Like Venice Beach vibes. Right? You're gonna go be
Arnold's, like, understudy.

Dan Holtz (07:26):
Everybody, when they'd hear the word first of
all, they couldn't say it. Mostpeople would say testosterone or
something, you

Roland (07:33):
know, and Believe it's Tostitos. Exactly.

Dan Holtz (07:36):
And and but people were so alarmed. And even I was
when I first heard I'm gonna beyou know, I'm supposed to be
putting something in my bodythat I was totally passionately
against. Because I worked out atGold's Gym for years and I saw
all the guys taking all thedrugs and all that. And I always
thought I'm never gonna doanything like that because I

(07:59):
want to live a long healthy lifeand I viewed it as all negative.
So I really had to rethinkthings.
But I started really thinkingabout how it goes with humans.
And you know, if you think aboutwomen, they hit menopause.
Right? Well, what is menopause?Well, it's when your body just
stops making estrogen andprogesterone and you just go

(08:23):
into this rapid, really hugeupset and decline.
And when you hot flash fromestrogen deficiency, that's
actually a stroke. People thinkthey go hot flash, oh, I had a
hot flash, they laugh about it.It's a mini stroke. It's

(08:43):
dangerous. Then I startedrealizing, well, if if this just
happens to all these women, Imean, age related decline is an
absolute fact.
You can't detox your way out ofit, there's everybody, you can't
peptide your way out of it. Youeither fix these age related

(09:05):
hormone deficiencies or you willnot have a high quality, high
functioning life. You just won'tfeel energy, strength, stamina,
drive. It's mental decline, it'sdepression, it's brain fog, it's
so bad that the transformationwhen I started down this path

(09:29):
was so profound. I feel sorryfor anyone that doesn't have an
opportunity that that hasn'treally found a really good place
to correct hormone deficienciesand treat them.
It's just such a profound lifechanging event if done properly.

(09:49):
And that's a key part of what Isay, if done properly. Know
because it's so important thathormones are powerful and you
got to do it right. You got tobe you know a healthy optimal
strategy with a really goodmedical provider that really
understands it's very important.

Roland (10:06):
Would you have the ability to explain what that
would look like? I. E. Someonewants to start some hormone
therapy and do it in a safe andresponsible way. Because I agree
with you.
They are probably the mostpowerful chemical messengers in
the body. Right. They can bewonderful, but they can also be
in excess, potentiallyhazardous. So, you know, someone
goes to the doctor's office.Right?

(10:27):
They get the routine blood work.And I read a lot of blood work
for people. And I see they doTSH, They'll do t four. They'll
do testosterone. Maybe they'lldo estrogen.
That's it. Is that enough, or doyou need to go deeper in terms
of gathering information so youknow what the person's current
physiologic presentation lookslike?

Dan Holtz (10:47):
The blood tests are pretty substantial. We at
Beverly Hills RejuvenationCenter we did a pretty elaborate
panel. You really got to look ata lot of different hormones to
really look at achieving optimalhormone balance. And it's
important to really get apicture of everything that's

(11:08):
going on. There's sex hormonebinding globulin, that's such a
critical factor if you don'tlook at that like you can when
you put hormones in the blood,the blood is just a storage
facility for hormones.
It's when they move from theblood into the cell that becomes

(11:28):
the important moment. Right?What you have in your blood
isn't so important as what'scapable of moving from the blood
into the cell. Sex hormonebinding globulin can be such a
limiting factor to that. So alot of people are misled.
They go do blood work and theysee that they're like for
instance with a male, theirtestosterone level is seven

(11:50):
fifty and they think they'redoing pretty Right? They've got
quite a bit of testosterone intheir blood. Well, when you look
deeper and you find that themajority of that testosterone is
bound with sex hormone bindingglobulin, it's it's it's a
completely misleading blood testbecause you think you've got all

(12:12):
these hormones that are able tobe utilized and they're not.
Your body is binding them all upand leaving them sit in the
bloodstream because the body isso overstimulated already that
it doesn't want to allow thosestimulants to go into the cell.
Then you start asking people howmany cups of coffee do you drink

(12:33):
a day?
And they say, oh, only six.Right? Only. And then you start
going, hey, look, your body isso grossly overstimulated with
you're you're taking in so manystimulants that your body wants
to down regulate, reduce theproduction of and the absorption

(12:53):
of energy producing hormonesbecause it's already so
overstimulated that it says Ican't take this. It's too much
stimulation.
So by drinking lots of caffeineand energy drinks and that, you
can completely destroy yourability to make hormones
properly. So that's just onequick little, you know, thing to

(13:15):
look at and understand how justthat one thing alone can affect
and matter of fact, I think it'sone of the major things that's
going on in our youth today.They drink all these energy
drinks and all this stuffthinking that now I'll have
energy. It completely depletesyour hormone production and your
hormone absorption. So it's ashort term gain and a long term

(13:38):
loss for sure.

Roland (13:39):
I often when I'm at a gas station, you have to go
inside and pay for gas beforeyou pump. Right? And I've
noticed that the energy drinksection at a gas station is now
an entire wall. Everyone and andtheir mother makes an energy
drink company or a brandnowadays.

Dan Holtz (13:53):
That's

Roland (13:53):
right. And I do believe that is a really wise statement
in terms of a symptom of oursociety because the human
nervous system wasn't alwaysmeant to be mashing the gas
pedal twenty four seven and, youknow, the the more you deplete
reserves of energy, the harderit is to heal. The lack of
capacity to heal directlycorrelates with the development

(14:15):
of illness Yeah. And chronicityand degeneration. So that's a
really wise point.
But you use an example there fora male. Right? So Yes. A man
with high testosterone Mhmm.They have this protein in the
blood that holds thetestosterone hostage for lack of
a better description.

Dan Holtz (14:28):
Females have it too.

Roland (14:29):
Sex globulin. With females, is the pattern the same
or is there some difference withwomen because they have a little
bit more of a complex endocrinesystem?

Dan Holtz (14:37):
Yeah. Well, the sex hormone binding globulin works
the same, men and women, it doesthe same thing. What happens
with women okay. So society haschanged so much over the last
forty, fifty years. Women usedto make babies all the time.
Right? So now that was what theywere supposed to do. And when

(14:58):
they were making five, six kidsover the course of twenty years,
know from say 20 to 40, theirability to make progesterone
stayed optimal and they rarelyhad progesterone deficiencies.
Well now because women arehaving one, maybe two kids at

(15:21):
best and sometimes none, theydevelop these progesterone
deficiencies in their latethirties all the way to
menopause. So say from 40 to 52,you almost don't find a female
these days that does not havesome degree of progesterone

(15:42):
deficiency.
Now if you leave that woman withprogesterone deficiency, her
anxiety, emotional sensitivity,and it'll just get worse and
worse and worse the older shegets, the closer she gets to
menopause. It'll get to thepoint where it can be just, it

(16:05):
just kind of ruins your life.Your ability to cope and
function just goes away and thenheavy bleeding starts to occur,
right? Now there's so muchbleeding that there's then
anemia sets

Roland (16:21):
Iron loss and such, yeah.

Dan Holtz (16:22):
Iron loss is severe and you know there's so many
people that are starting tolearn about this now. They're
starting to learn that theseprogesterone deficiencies are an
issue and something that needsto be treated. The problem is a
lot of practitioners think theycan treat that deficiency with

(16:43):
micronized oral progesterone.You cannot. You will never
succeed treating an estrogendominant female with oral
progesterone.
It does not work, it will notwork. You will never achieve
hormonal balance unless you'reusing a transdermal application

(17:05):
and literally putting so acream, right, and you're loading
it into the tissue rather thantrying to absorb it through the
bloodstream. It just neverworks. But I saw so many amazing
miracles at Beverly HillsJuvenile Hall for twenty two
years watching these women gettheir life back, get their
health back. You're talkingabout weight loss, fluid loss,

(17:29):
the brain goes calm.
Now we can sleep. Now we can getwomen were getting they'd come
close to menstruation. Theywouldn't even know their period
was coming. They felt so good.So just that one hormone,
progesterone, can be a lifechanger for females.

Roland (17:44):
I have a question about that just so I understand
properly. You said when womenwere having multiple kids over
the course of a couple decadesYeah. They were not running into
progesterone issues. No. Is itbecause of the the multiple
pregnancies or is it alsobecause, you know, society was
different, the the state of theworld was less toxic, there were
less interferences within thingslike electromagnetics and their

(18:06):
stress levels were dramaticallylower, or is there something
about multiple pregnancies thatregulate the female physiology?
Well,

Dan Holtz (18:13):
you're right. There's lots of factors. Yeah. So it's
not just the fact that they'renot having multiple babies, but
when I would see there'stoxicity, there's radiation,
those are all factors, right? Soit's all a piece of the puzzle.
But I will say when I ran thatbusiness, rarely did we see a

(18:37):
woman come in that had had fivekids between 20 and 40 that had
progesterone deficiency.

Roland (18:42):
Really? That's fascinating.

Dan Holtz (18:43):
So there there's no question that it's a huge piece
of the puzzle. And and buttoxicity and things and
radiation is always a factor.

Roland (18:52):
So to me And

Dan Holtz (18:53):
stress, of course.

Roland (18:54):
Oh, stress is the driver of all things that pushes you
out of balance. Right? But tome, it sounds like a woman who
has had fewer kids or no kidsthey may have to be more mindful
of making sure that they'regetting themselves checked on a
regular basis to see if thereare these deficiencies, this
term estrogen dominance that youuse in relation to being

(19:14):
progesterone deficient.

Dan Holtz (19:15):
And you know what? You don't even need to get
checked. All you have to do ispay attention to how you feel.
Because obviously before youtreat it you've to get checked.
But here's the reality.
If a week prior to menstruationyou're feeling anxiety,
emotional sensitivity, breasttenderness, lower abdomen

(19:37):
distension, sleep disorder, andjust feeling like you literally,
you know, are about to lose yourmind and on things that normally
just don't really bother you atall, you are at that point in
life where you're ready to starttreating your progesterone
deficiency. And if you treat itand you treat it right, you can

(20:00):
live a life that's so highquality and so peaceful and so
good. Menstruation will go backto normal, you will not have
heavy shedding, you will nothave anemia, you'll get it all
under control and you canoptimize your health and your
body and cruise through your 40sin a very comfortable way and
live a very high quality life.And that's not the only hormone,

(20:23):
but of course that's one of thebig ones for women in there
between that say 40 to 52, it'sjust so important. If they could
only treat one hormone, I wouldsay fix that one for absolutely
certain.
Interesting.

Roland (20:37):
Yeah. That's a wonderful piece of advice. And most people
think hormone balancingtestosterone, estrogen,
progesterone is the immediateassociation. But you know we
have these other hormones thatare protein hormones, peptides,
have thyroid hormone, we havegrowth hormone, we have insulin
and like you, I've studied a lotof this stuff. I don't actually

(20:59):
do it as a practice but for theclients I've been working with I
needed to know what is theirbody signaling like because if
there's a signaling issue, itdoesn't matter what you do with
diet or supplementation, there'sa fundamental issue that has to
be addressed in some capacity orit can be an indication of maybe
giving you context on whatthey're experiencing symptom

(21:19):
wise but it seems everyone has athyroid problem nowadays.

Dan Holtz (21:22):
Everyone has a they

Roland (21:23):
have an autoimmune thyroid problem with Maybe they
have growth hormonedeficiencies. How do you look at
these non sex hormones but justas important because work in the
network. They help anchoreverything in that balance,
right?

Dan Holtz (21:37):
Well just talking about thyroid if we wanna if we
wanna you know we could spendthe next six months sitting here
right at this table.

Roland (21:46):
Can I put on my color hat for this part of the
conversation?

Dan Holtz (21:48):
Exactly, right? It could go on and on and on. But
just think about one thing. Justthink about well first of all,
if you're estrogen dominant, ifyou're a female and you're
estrogen dominant, you areabsolutely gonna have thyroid
dysfunction as well. When youoptimize that progesterone
deficiency, thyroid function isgoing to improve because of the

(22:10):
whole sex hormone bindingglobulin piece.
I want to say something aboutthyroid that I don't think too
many people think about. And Ithink it's kind of important to
just explore and just thinkoutside box a little bit. When I
walk on my hands my shoes last along time. Right? You mean

Roland (22:36):
you don't wear shoes on your hands when you're walking
on them? Right.

Dan Holtz (22:39):
But see see how ridiculous that sounds. Right?
But but the truth is if I walkedon my hands my shoes would last
a long time. That's the plusthat would come out of walking
on my hands. But it'sridiculous, of course nobody
ever would.
But there's always somethingthat's a plus that comes.

(22:59):
There's a plus and a minus foreverything. Right? So let's talk
about fasting for a minute.Let's talk about fasting.
Let's see what is fasting? Whatare the pluses with fasting? Are
there pluses? Of course there'spluses. There's some indication
that you may be able to reducethe risk of certain cancers with

(23:21):
fasting.
There's body fat reduction withfasting. There's ways lot to
look at fasting and say well Ifast and it helps me in this
way. But if you think a littledeeper and you think about how
the body works, if you walkaround barefoot on a rough

(23:45):
surface you're going to developreally thick skin on the bottoms
of your feet. Your body is goingto sense there's a rough surface
that that skin is touching allof the time. We cannot afford to
leave soft tissue there anymore.

(24:06):
We have to thicken the skin, wehave to now make it so that this
creature can make it across thisrough surface time and time
again. So we're going to makethat skin on the bottom of the
feet very thick, right? So thebody's going to adapt. If we go
into a hot room, the body'sgoing to say well it's too hot

(24:28):
in here, we got to start pushingmoisture out of the pores,
right? It's going to sweat tocool.
If we go into a cold room it'sgoing to shiver to make heat. So
I want to just make youunderstand that if you're not
drinking enough fluid the bodywill retain fluid because you
taught the body that fluid isscarce. If you teach the body

(24:52):
that food is scarce, right,fasting, body says it's time to
eat and you go, no, I'm notgoing to eat. Well, body can
only assume that you have pooraccess to food. It doesn't know
that there's food right overthere in the counter.
It says, well if food is scarcewe absolutely cannot afford to

(25:17):
be able to convert food toenergy rapidly. So we have to
reduce thyroid functionimmediately. We have to turn
this human being into a personwho metabolizes food slowly
Mhmm. Because the person woulddie quickly if they have poor

(25:38):
access to food and, you know,that it so a rapid metabolism
would be rapid death. So knowthis, when you're fasting, I'm
not gonna argue that there's nogains, that it's impossible to
have any pluses, but youabsolutely create thyroid
dysfunction.
And the more you do it and themore often you do it the worse

(26:02):
the thyroid dysfunction gets. Somany people are so busy and they
don't have time to feedthemselves and their thyroid
function gets worse and worseand worse. I try to tell people,
look, if you want to teach thebody anything, teach it that
food is plentiful. Take verysmall amounts of food every hour

(26:25):
for sixteen hours and watch yourthyroid function start to
improve because small frequentfeedings teach the body that
food is plentiful. It doesn'tmean eat more than you should,
but if you're if you're takingin 1,600 if you're a woman and
you're taking in sixteen hundredcalories over a sixteen hour

(26:46):
period, boy, in a 100 caloriesan hour, boy, you've sure taught
the body that food is plentifuland the body can certainly
afford to raise the metabolicrate up now, can't it?
And it absolutely will. Now ifyou have selenium deficiency, if
you have other issues, toxinsand things, those are all

(27:07):
factors. But I do know that withpeople that I got, I taught them
how to take small frequentfeedings and start introducing
it. You know, you can see overthe period of months, you can
start to see thyroid functionreally start to improve. So it
can it can really help turnthings around.
So just that's a little quickthing I wanted to share with you

(27:29):
about thyroid function that I'veseen over the years.

Roland (27:31):
Well, I have two things to say to that. Number one,
fasting as it's classically beendone in human society has been
paired with a downregulation ofenergy expenditure. Mhmm. When
people fast for whatever reason,classically, was for healing or
religious beliefs or whatever,and you would down regulate the

(27:52):
amount of energy you're burningto match the the activity with
what your physiology was readyfor. You know, if I wanna go on
a cross country trip and I havea quarter tank of gas in my car
and I don't plan to go to thegas station, I might not make it
out of my state.

Dan Holtz (28:06):
That's right.

Roland (28:07):
So the body is, as you said, is only responding to
input signals and it's givingyou feedback based upon the
signals. So the average personwho's doing intermittent
fasting, it's like I'll slam mycoffee in the day, I'll race
through my morning, I'll do asmuch work as possible, and then
there's a deception there. Whenthe body's under stress, it
starts making stress hormones,cortisol, adrenaline, things of

(28:29):
that nature, which increase yourblood sugar. Naturally, you
break down whatever's stored inyour body so breaking down some
muscle mass but cortisol has aeuphoric feeling in the body
because there's an antiinflammatory effect to cortisol.
There's also euphoric feeling toblock pain and stress.
Sure. Makes you feel that way.And people say, oh I feel great,
I'm clear. It's because yourbody's under stress. That

(28:51):
clarity is actually you being infight or flight but there's no
panic that's actually in frontof you but your physiology
believes there is becausethere's a food scarcity.
That's the first thing I have tosay. The second thing is from a
thyroid perspective, if youchronically trash your thyroid
then the body gets into thepatterns of those things. That

(29:13):
is the one button that getspressed that creates a cascade
of all other things becausewithout thyroid function, there
is no energy. Without energy,you can't make all these
molecules that you're talkingabout. So I think this is such a
wonderful topic for people tolisten to.
We're not bashing intermittentfasting. We're saying set and
setting, time and place basedupon the goal and the outcome.

(29:35):
Would you agree with thatstatement?

Dan Holtz (29:36):
Yeah. When your body has to convert itself back to
food it uses adrenaline to causecellular inflammation which then
cortisol is attracted toinflammation. The body says,
well there's no food, so we'regoing to convert the body back

(29:59):
to food. So we're going to pushepinephrine into that cell which
causes cellular inflammation.Now cortisol is floating by in
the bloodstream and cortisolsays, well, look at that.
There's cellular inflammationthere and I'm cortisol, I'm an
anti inflammatory, I'm attractedto inflammation. So it migrates
into that cell, converts thatcell, it catabolizes that tissue

(30:21):
and of course push it. Nowyou've got fuel right back in
the bloodstream. The glucosegoes up because you're
catabolizing fats and muscle andyou know you're converting the
body back to fuel. But whatpeople also don't understand is
that you're using so muchadrenaline and so much cortisol

(30:43):
to cannibalize all this tissueby the end of the day you don't
have very much adrenaline leftand you don't have very much
cortisol left.
So guess what you're going tobe? Stiff, tight, inflamed. Very
frequently people their adrenalglands just can't keep up
because your body was reallynever designed to just

(31:07):
metabolize itself all the time.Hey, if you ran out of food once
in a while, could that system beutilized to get you to survive?
Yes.
But when you start doing it allthe time, now you got to produce
twice the adrenaline that yourbody's used to producing. Your
adrenal glands start gettingtaxed, and you gotta make twice

(31:30):
the cortisol you were you youknow, you were making. And you
start to get adrenal fatigue tothe point where your body just
can't keep up. Well, you'll knowit real fast because you'll
start getting so stiff and tightand inflamed by the end of the
day. I mean, how long can youkeep doing that before you put
so much stress on your adrenalglands?
Because yeah, there's no stresson the thyroid anymore you're

(31:52):
not hardly making any thyroid,but now you've doubled up on
your adrenal glands and man itjust is really brutal for the
adrenal glands to try and keepup with that kind of adrenaline
and cortisol production. Andthey just don't. So you get
stiff and tired and you'rewondering why am I so inflamed?
Well, that's why.

Roland (32:13):
Which is really a symptom of modern society that
most people are probably goingthrough. Maybe this is that
light bulb moment. So in sayingthat and all this stuff about
hormones cause I want to roundout the hormone piece before I
ask you about the next categorywhich I think is going to be
very interesting for mostpeople. Does everyone have to do
exogenous hormone balancing inyour opinion? I know it's a

(32:35):
loaded question but in yourprofessional opinion given what
you've seen done andexperienced, where do you think
the average person who may bestruggling is on the spectrum of
yes versus no?

Dan Holtz (32:48):
Well I'll tell you one thing. If you want to have a
high functioning, high qualitylife where you want to feel
amazing energy every day and youjust want to say you want to be
the guy that works every day andlifts weights and you wanna be

(33:08):
the woman that you know that hasthis energy, it goes to the gym
and just pushes. If you wanna besomebody that's gonna be really
fit, really in shape and haveamazing energy and feel really
really good all the time, I donot see how you could achieve
that without by age 40, whetheryou're male or female, engaging

(33:34):
with a really good medicalpractitioner that understands
how to optimize hormones, by thetime you're 40, you've got
enough age related decline, youare not going to have many
people that are gonna befunctioning at a very high
level. Once they get into theirmid forties, they're already so

(33:57):
impacted by age related declinethat the quality of life drops
so much. If you're fortunateenough to be able to afford to
add this into your life.
I mean, I've been doing it fortwenty five years. I'm 65 years
old now. I go to the gym everyday. I have unlimited energy. I

(34:19):
have arguably too much energy.
You know what I mean? I there'snever a shortage of that. And I
just think about how lucky I'vebeen to be able to spend the
last twenty five years. Now, Ialways manage my hormones to
keep them in the optimal level,right? But there's costs

(34:39):
associated with it, know, noteverybody is able to do it's
unaffordable for some.
But with those people I wouldjust say be careful with the
energy drinks, careful with thecaffeine, walk a lot, don't run
a lot, don't stress the bodyreally really hard, just treat

(35:02):
the body really good, reallygood rest, small frequent
feedings, all that kind of stuffis for people that can't
necessarily afford to optimizethe hormones, you know, take it
easy on the body, don't pushyourself so hard and certainly
stay away from all thestimulants. But movement is
good, rapid movement isinflammatory. So move the body.

(35:25):
Walks are very important, know,and some resistance exercise is
critical for having optimalhormones but if you're not
optimizing hormones bysupplementing you gotta be
careful you don't push it toohard.

Roland (35:39):
Which is a great message because most people focus more
on the training and the stressin terms of priority than they
do the recovery aspect. Yeah.And I mean, I'm you're talking
about age 40. So I'm 39 now. I'm40 this year.
Alright. And there's still partof me that goes, I can train
like I did when I was 30 or 20because you know, there's the
old saying Clint Eastwood had,like don't let the old man in.

(36:01):
That's a secret to never gettingold. Yeah. Part of that is the
expectation of well, I've alwaysdone things this way and I'm
conditioned in my twenties andthirties to be able to expect an
outcome, it does start to shiftas you And get to sort I've had
to have this own kind of come torealization inside of myself

(36:22):
that I need to it sounds cliche,you need to work smarter not
harder with the times you chooseto stress yourself both with an
exercise but also withschedules, with commitments,
with how much you're just on thego versus how much you're
actually able to take some timeand enjoy the stillness and
enjoy the quiet.
Yeah. Which is actually a hardpractice for most people because

(36:45):
of how we're conditioned.

Dan Holtz (36:46):
Oh, it's great.

Roland (36:47):
You said even at 65, you have to catch yourself every so
often.

Dan Holtz (36:49):
Right? Yeah. People push themselves so hard. Mhmm.
You know, if nothing else, evenjust mentally what they do to
themselves every day.
You know, that they beatthemselves to death with
negative thoughts and andtorture themselves with so many
people get in these patterns.And you know if you could just

(37:09):
just try to get out of thatstate, treat the body better,
treat the mind better, try tofocus on what you want. Tony
Robbins says we get what wefocus on, right?

Roland (37:23):
He's so right about that.

Dan Holtz (37:26):
Just have to be so careful about what you do with
your thoughts and your mindset.You know? Get back to gratitude.
Get back to just lovingyourself, loving your life,
treating yourself good. Youknow?
And don't don't beat yourself todeath all day with physical
stress and mental stress andYeah. Just try to kinda give
yourself a little peace. Right?Go to the EE system once in a

(37:48):
while and relax.

Roland (37:49):
Go to regenerative health system specifically. But
it's funny, you know, we'retalking about hormone balancing
and antiaging Mhmm. But youcan't get away from the basics
of the things that are alsofree. You talked about the cost
associated with things. Yeah.
It doesn't take any money to benicer to yourself Yeah. Or to
give yourself an allowance tomaybe not do that extra thing
and be super productive. So Ilove that you shared that

(38:10):
because it's not just thisexclusive high cost service that
you're pushing. You're like,look, if you wanna do this
great, but this is not areplacement for that. This will
help you compensate if you can'tdo this stuff, but this is
foundational.
Yeah. So I love that becauselast time I checked in, you
know, the blue zones ordifferent parts of the world

(38:31):
where they're not so obsessedwith status and wealth and
productivity, the reason theylive a long time with that
disease is because they justdon't stress.

Dan Holtz (38:40):
That's exactly right.

Roland (38:41):
It's so simple.

Dan Holtz (38:42):
You do more damage I think with your thoughts people
do in a day than it's justamazing how much you can destroy
yourself. Just thinks they haveto be, you know, a billionaire
and a you know, everybody youknow, people don't spend enough
time just being grateful for whothey are and what they are and

(39:05):
just focusing on being the bestversion of themselves that they
can be. Just give yourself abreak, you know, take it easy
and just try to just be the bestyou you can be. Don't compare
yourself to Elon Musk. You'reyou're just you are who you are
and just be the best version ofyou that you can be.

Roland (39:23):
Yeah. Comparison of yourself outside of yourself is
never gonna yield a positiveresult. Only compare yourself to
you if you even want to do that,but, you know, I believe that
there's few things moredangerous than the unguarded
mind for someone's lack ofwell-being. So thank you for
that.

Dan Holtz (39:38):
Completely agree with that.

Roland (39:40):
Wanna shift gears on you a little bit here, Dan, because
this word peptides seems to bethe new thing nowadays. Right?
So we talked about hormonesfoundational within the concept
of anti aging and longevitymedicine and healthcare. What
about peptides? Like what arethey?
Do they have good utility? Arethey the next fountain of youth

(40:01):
or are they kind of a fad thatyou think is passing through?

Dan Holtz (40:04):
No, they're definitely not a fad. Definitely
they have value. The more thatwe learn about peptides, like
there's like 7,000 differentpeptides. I mean it's really
amazing how, you know, when youstart to look at how the body

(40:24):
it's really cellularcommunication. It's it's the
body, you know, communicatingwith these peptides.
These little proteins aresending the messages around the
body that you need. Do believethat of course I utilize various
peptides myself. I do believethere are some that are real

(40:44):
valuable. I think if you startwith your basic fundamentals
getting your hormones optimized,that's step one to me. I think
for most people you can go sofar with that that you can feel
so good.
And then if you happen to havethe financial ability to invest

(41:05):
and go further and you wanna domore, sure. You take a BP one
hundred fifty seven or a TB fivehundred or some of these
messengers that are going tohelp the body heal, recover,
repair quicker. Everythingdiminishes as we age. Our
ability for cellularcommunication goes away too. Now

(41:28):
hormones are important with thatbut peptides are also important
with that because they canimprove that cellular
communication so much.
Some of these peptides canreally make that extra
difference. I know so manypeople that had a knee or a
shoulder or something that justbothered them all the time and

(41:49):
they took one shot of BP onehundred fifty seven in the joint
and boom. And three weeks lateran injury that was going on for
two years and they're over itand they're just shocked. So you
can't deny that there's valuethere, that there's but like
anything there's quality ofpeptides. There's totally

(42:12):
different qualities.
There's some that work very welldepending on how they're
manufactured. Some have a verypoor shelf life and they don't
last long in the body, otherslast a long time. There's just a
lot to know. You could spend sixmonths in this room right now

(42:33):
talking about peptides andscratch the surface. So there's
a lot to know.
Take your time, do yourhomework, make sure that you're
getting really high qualityproducts. Made everywhere now
and there's such a variation inthe quality and it's important
to get the right peptides to dothe right thing but there's a

(42:56):
lot of opportunity there to takeyour health to another level.

Roland (42:59):
So I know with hormones Mhmm. Excess is potentially
dangerous.

Dan Holtz (43:03):
Oh, yes.

Roland (43:04):
Is the same true of peptides? Is there a a downside
or a potential nefarious elementto them in your opinion?

Dan Holtz (43:12):
Yeah. I think that you can overdo I mean, you can
kill yourself drinking too muchwater. Yes. Once you know that,
you know

Roland (43:22):
Dose makes the poison.

Dan Holtz (43:23):
Absolutely. And so like anything, like with
hormones, I see hormones done sodangerously, so often. Like for
instance, just a quick example,testosterone with men. They'll
take a big old shot once a weekand blast their levels 12 in
100. Exactly right.

(43:46):
And think, yeah, it's fine.Well, along with that huge spike
comes an estradiol spike. Theconversion of testosterone to
estradiol goes through the roof.And now you're walking around,
you got somebody that are beetred because they've their
estradiol level is twice what itshould be. And their
testosterone levels up attwelve, thirteen, fourteen,

(44:06):
fifteen hundred.
And now they're making so muchhematocrit. Their their blood is
getting so thick and they'rewalking around with their
hemoglobin and hematocrit atlevels that are so high that
their blood is so thick it'sbarely moving. Their blood
pressure goes through the roof.It's so dangerous and so

(44:29):
horrible to do those types ofhormone programs. You gotta be
careful, you gotta be smart.
If you check my blood in thelast twenty five years, any day
of the week you check my bloodlevel, it would never be out of
the normal youthful healthyrange which was 1,100 was of

(44:53):
course if you use a LabCorp,anywhere up to 1,100, anything
over 1,100 they considered to betoo high. I never ran my
testosterone over a thousandever and usually nine fifty. And
you know, again, just it canreally produce longevity, high

(45:13):
quality of life, or you candestroy your life with hormones
too. You can use themincorrectly, get bad advice, get
sloppy, don't keep an eye onyour blood tests and you can
just destroy yourself in a fewyears, have a massive heart
attack or a stroke becauseyou're not doing things the way

(45:33):
the body was designed to dothem. I mean there's reasons why
we don't walk around with bloodlevels of testosterone to 1,500.
There's massive side effectswith that that go along. Very
dangerous, it scares the hellout of me when people and they
don't get tested and they justdon't utilize hormones in the

(45:53):
way they should. Be very carefulwith them. Get great advice from
people that have been doing itfor twenty years, people that
really understand how to treatthis and, really good guidance
is really important.

Roland (46:09):
I I absolutely echo that because in my perspective,
mother nature doesn't make amistake. Everything has its
intelligent design, its checksand balances system. And it's
often when the human brainthinks it knows better than,
shall we say, intelligent designmixed with years of research

(46:29):
that have correlated justknowledge of where things should
and shouldn't be. I think that'sreally wise advice too because
you can't unring some bells whenyou've hurt yourself, you know,
physiologically speaking.

Dan Holtz (46:42):
Yeah. And they're and peptides, we don't know a ton.
Yes. That's

Roland (46:47):
the thing I've always thought. There's no long term
data yet because we only haveshort term reality.

Dan Holtz (46:52):
We have short term. I don't think there's any major
concerns if again really goodguidance from people that really
understand it and stay on theconservative side. You know just
don't go diving into the pointwhere you're just overdoing and
you know, there's so many peoplethink more is better with

(47:14):
everything and it's just not.You just be careful, be
cautious, on the side ofconservative and try to make
little improvements along theway. And of course ten years
from now we're gonna know a lotmore about peptides than we know
today and we'll have more datato say is there any potential

(47:35):
negatives?
Mean, that's the problem withany of this. Twenty five years
ago when I was starting onhormones, there wasn't a lot of
data to go on. So now I'm a longterm study. I'm a twenty five
year study And here I sit at 65,I feel good that I went down
this road. I feel like it wasthe right choice for me.
I feel like I wouldn't reallyhave changed anything that I

(47:57):
did. I felt like I made somesmart moves. But honestly,
twenty five years ago, Icouldn't tell you, I couldn't
look you in the eye and tell youI knew for certain that what I
was doing was gonna producehealth and longevity. I didn't
know. But I thought one thing'sfor sure, I'm gonna do it
conservatively just try to notdo excessive levels.

(48:20):
And that made most sense to meto at least try to on the side
of you know being a little alittle conservative so that if
there was any downside you knowmaybe I wouldn't put myself at
so

Roland (48:33):
much risk. Yeah. Wise perspective for sure. Yeah.
Thing I wanna ask you Dan iswhere the antiaging longevity
field is going in your opinion?
Are there there new thingscoming out? Are there things
that people should be mindfulof? Any insights that you can
give people who are reallywanting to know what the next
cutting edge thing might be?

Dan Holtz (48:54):
Well David Sinclair came out a couple of weeks ago
and said they're now takingcells and reversing the age of
those cells seventy five percentin six weeks. Now I don't know
exactly what he's

Roland (49:12):
So it's a true mystery.

Dan Holtz (49:13):
But there really, there's leaps and bounds in this
longevity space right now whereI think if you're gonna be alive
another ten years, you'reprobably gonna be able to live
another hundred years. Mhmm. Ithink there's so much that we're
learning and of course with AIit's just gonna get even more

(49:36):
intense. Now we have, also cellfactors that are basically
they're so think of the peptidesas communicating with cells and
creating proper messaging forhealing and that. Well now we
have cell factors that arespecifically they're recreated.

(49:58):
When we were in our teens we hadthese very specific proteins
floating around in our bloods,these cell factors that told our
stem cells what to do. Well aswe got past age 18, the amount
of those particular cell factorsdropped off dramatically. So
your ability to heal, repair,regenerate dropped off a great

(50:21):
deal too. Well now we have thesecell factors and we can put
those back in the body and wecan make our stem cells start to
communicate again like they didin our teens, you can literally
regrow joints, you can regrowthere's really, in my opinion

(50:41):
from what I've seen in the lasttwo years working with cell
factors, you don't need to doknee replacement, hip
replacement, shoulderreplacement anymore. These cell
factors are capable ofregenerating joints in such a
way without even adding morestem cells to your body.
Just getting those properprotein messages in the system

(51:03):
with these cell factors, you'reliterally able to regrow a joint
in a very short period of time.So it's really shocking what
we're seeing now. I think jointreplacement is a thing of the
past already. Just don't I meanunless you've got bone on bone
and you've had bone on bone forso many years, there's not a

(51:26):
speck of cartilage in a joint toregenerate. You can actually
regrow that cartilage even ifit's a little teeny bit left
with the cell factors, you canregrow that cartilage in that
joint and without even replacingthat joint.
So the orthopedic world isreally changing right now. Now
that we have access to thesecell factors, and as long as

(51:48):
you're below 65 years old, yougot plenty of live stem cells,
you put those cell factors in,that body will regenerate
tendons, ligaments, cartilage,bone, anything, nerves. It's
amazing. Organ regeneration withthis stuff. Like, it's it's
absolutely profound what we'reseeing.

Roland (52:08):
Without the barbaric hacking up of the body and and
the trauma that comes associatedwith

Dan Holtz (52:14):
that. Yeah. I wouldn't dream of getting a
joint replaced anymore. And Iwould not add I wouldn't add
stem cells. No reason to.

Roland (52:22):
Interesting.

Dan Holtz (52:23):
With the cell factors, you just don't need to.
Very interesting. Pretty cool.

Roland (52:27):
Something that I think I'll have to dive into a little
bit more to understandmechanistically, but it's a very
intriguing concept.

Dan Holtz (52:32):
So if you think about exosomes and what they were
supposed to do, exosomes

Roland (52:36):
are actually very quickly define stem cells and
exosomes for maybe those who'veheard the words but they don't
know what they mean?

Dan Holtz (52:41):
Yeah. So stem cells are the cells that actually do
the work that make the, youknow, repairs and regeneration.
But without being told to do it,they won't do it. And and that's
the problem. When you're 50years old, you got plenty of
stem cells to do the work ifsomebody would just tell them to
go do the work.
Well, so exosomes came along.And what are exosomes? Exosomes

(53:05):
are messages. They're cellfactors. The problem is they're
random cell factors.
They're not the same exactmessages that we had in our body
when we were in our teens. Sonow we have that same group of
cell factors that we had in ourteens. Those are identified now,

(53:26):
and now we have this specificarray of the proper messages. We
don't have to just blast a bunchof exosomes into the body and
hope that we get the rightsignal. We can make sure we get
the right signal because now wehave the correct cell factors to
utilize to get a result each andevery time.
You don't have to just hope thatyou get a good message from an

(53:46):
exosome. You use the right cellfactors, right messages, and get
a major change every time you doan injection. Wow. Pretty cool.

Roland (53:55):
I mean, that sounds almost like too good to be true,
but I know it's not.

Dan Holtz (53:59):
It's the next evolution beyond exosomes. It
takes healing to a whole newlevel and joint regeneration.
And yeah, it's just now we'rejust at a whole another level.

Roland (54:10):
And if people want to know more about this, this is
your world in addition torunning regenerative health
systems, right? You have theability to guide people through
the process, procure these kindsof molecules and and remedies
for people. Correct?

Dan Holtz (54:24):
Yeah. Yeah. Yeah. I'm actually you know, now that I've
kinda stepped away from runningthe business, I sold Beverly
Hills Rejuvenation Center a yearago and now I'm a minority owner
and I've got a bunch of time onmy hands. So I'm kinda taking a
different strategy here in mylife.

(54:44):
I've got all this informationthat I accumulated over the
years and I wanna share it withpeople and I wanna help people
and I wanna continue in thisregenerative world. Yep. So I'm
creating a website,danholtz.com, that 'll be up in
a couple weeks and where peoplecan go on there and they can

(55:05):
communicate with me and getinformation. And so at least I
can stay in the loop and andcontinue on and and, you know,
share with people what I'velearned and what's new and
what's coming down the pike andjust kinda keep, keep in touch
with everyone. So

Roland (55:22):
I love it, Dan. And and and the thing that's so cool is,
you know, you said you're 65.You still have this zest for
knowledge, this thirst forlearning more. The passion is
evident. And I've never heardsomeone break down the
mechanisms of all the things inantiaging so well.
It's clear that you've reallydedicated your life to this. So
Well, thank you. Thank you forsharing all this information

(55:43):
with all of us. If there is morewhen the website's up, I'm sure
people can contact you there aswell. Sure.
But you're also within thefamily of the energy enhancement
system. You've got a beautifulplace in Las Vegas.

Dan Holtz (55:56):
Love the EE system technology. It's changed my
whole life. It's it's just takenmy life to a whole another
level. I'm so happy to be a partof it and I don't know what I'd
have done without it really.It's it's so much a part of my
daily routine

Roland (56:10):
Mhmm.

Dan Holtz (56:10):
To charge my cells up and and be able to optimize
energy, healing. It's just awhole another level of of
intelligent healing. You knowwhat I mean? So I'm very
grateful to have this technologyand and love it.

Roland (56:27):
Yeah. You're approaching it from both ends. So Dan,
again, I wanna thank you foreverything. It was an absolute
pleasure to listen to you. Ilearned a lot and I hope
everyone else did.
I hope it demystified this wholelongevity and antiaging aspect.
If these things resonated withyou, you can reach out to Dan or
inquire about more information.And as always, please do like,
share, and subscribe. We arebuilt based upon the message

(56:50):
being shared with those. So ifthis does resonate with you or
anyone that you think shouldhear it, please do let them
know.
And And as always, we'll see younext time on the Everything's
Energy Show. Take care.
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