Ep 291: Timing is Everything: How Docs Prepare You for Frozen Embryo Transfer

Fertility Docs Uncensored is hosted by Dr. Carrie Bedient from the Fertility Center of Las Vegas, Dr. Susan Hudson from Texas Fertility Center, and Dr. Abby Eblen from Nashville Fertility Center. In this episode, your Fertility Docs unpack the different ways patients can be prepared for frozen embryo transfer (FET) cycles—because there’s more than one path to pregnancy. From fully programmed cycles to completely natural approaches and modified natural protocols, the docs explain how each option works, what medications may be used, and the pros and cons of each. In a programmed cycle, the endometrium is carefully prepared with estrogen and then progesterone, with timing of the progesterone being critical to ensure the embryo is transferred during the ideal window of implantation. Natural cycles allow the body to take the lead, using ultrasound or ovulation kits to pinpoint ovulation and then timing progesterone and transfer accordingly. Modified natural cycles use letrozole and a trigger shot to encourage follicular growth, followed by progesterone support. While the approaches differ, success rates are similar—and the key takeaway is that there isn’t a single “right” way to prepare for FET. The best choice depends on your body, your doctor, and your unique journey. This podcast was sponsored by Shady Grove Fertility.