All Episodes

December 4, 2025 123 mins

What are the most EXTREME lifeforms on Earth, and how are they surprisingly important to study? And what is the long yet recent history of astrology, and why do we reach for it?

Things we Talk About:
The Seal Stream
Sea lion running

Timestamps:
(00:00:00) Intro
(00:04:23) Extremophiles
(00:57:55) Astrology
(01:43:59) Outro

Support us with a Max Fun Membership!

Join our Discord!

We also learn about: 

We’ve put tardigrades through every red bull task imaginable but they’re NOT extremophiles, extremotolerant vs extremophiles that thrive, thermophiles at 122 celsius, anglophiles, what would it suck to experience, psychrophiles, acidophiles and alkaliphiles, hypobarophiles experiencing 500x our pressure, oligatroph, polyextromophiles, life has found a way in so many extreme places, the chernobyl black mold, not just growing towards radiation but eating Hot Particles, fungi have survived harsh radiation in the Earth’s past, melanin lets the fungi handle and perceive radiation safely, it’s similar to photosynthesis though in the same way a tsunami is similar to a glass of water, conan the bacterium can live inside nuclear reactors, DNA redundancy, krill that makes antifreeze proteins, osmoconfromers, acidophile taken to a lab and finally thriving at .7 ph, it’s also hard as hell to capture and study and keep these extremophiles alive, extremophiles gave us PCR, we also us extremophile e coli, bioremediation is what I took when I failed bio and was tutored by an extremophile, we have so much to do-actually that was pretty funny, bioplastics, what extreomophiles teach us about astrobiology, letting some bacteria chill on the outside of the ISS for 3 years, damn girl you’re making me re-evaluate the limits of life, our nuanced and conflicting feeling on astrology, yay we get to read our horoscopes- wait fuck why am I happy about that? babylonian horoscopes, star charts for things like seasons actually were right, the Enuma Anu Enlil collection of omens, what’s your mother’s maiden name and pincode horoscope,  the legacy of the endless pig, uh oh we’re having fun talking about horoscopes, medieval astrology in the royal court and the sciences, before we knew about the earth going around the sun the stars explained the seasons, in the 1700s astrology was seen as a sham, of course royal watching tabloids bring about astrology 2.0, scraping the bottom of the barrel for anything to say about princess margaret, globe conflict 2 electric boogaloo, a pims advert is a rich text, the horoscope test, god the people yearn for therapy, the barnum effect, zodiacs are part of our culture - so something to connect with, the correlation of uncertainty and horoscope popularity, how to manage uncertainty without horoscopes, video games offer a structure and challenge and reward that can help people cope with hard times.

Sources:
NOAA: What is an Extremophile?
Life: Extremeophiles and Extreme Environments
Nature: Life in Extreme Environments
PMC: Genomics of an extreme psychrophile, Psychromonas ingrahamii
The Biologist: Eating Gamme Rays for Breakfast
Research Gate: A Case Study of Strains Inhabiting Chernobyl Reactor No. 4
Chemical Communications: : The Incredible Cell Membrane Adaptations of Extremophiles to Harsh Environments
Life: Extremophiles and Extremophilic Behaviour
Biotechnology Advances: Structural Features of Thermozynes
Science: Conan the Baterium
Microbiology and Molecular Biology Reviews: Oxidative Stress Resistance in Deinococcus radiodurans
Polar Biology: Cold Resistance the Krill Euphausia superba
Extremophiles: Picrophi


Advertise With Us

Popular Podcasts

Dateline NBC

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

Are You A Charlotte?

Are You A Charlotte?

In 1997, actress Kristin Davis’ life was forever changed when she took on the role of Charlotte York in Sex and the City. As we watched Carrie, Samantha, Miranda and Charlotte navigate relationships in NYC, the show helped push once unacceptable conversation topics out of the shadows and altered the narrative around women and sex. We all saw ourselves in them as they searched for fulfillment in life, sex and friendships. Now, Kristin Davis wants to connect with you, the fans, and share untold stories and all the behind the scenes. Together, with Kristin and special guests, what will begin with Sex and the City will evolve into talks about themes that are still so relevant today. "Are you a Charlotte?" is much more than just rewatching this beloved show, it brings the past and the present together as we talk with heart, humor and of course some optimism.

Stuff You Should Know

Stuff You Should Know

If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.