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November 17, 2025 61 mins

Does a little alcohol really make you speak a foreign language better? This week we unpack a quirky randomized trial that tested Dutch pronunciation after a modest buzz—and came to the opposite conclusion the researchers expected. We use it as the perfect holiday case study: instead of arguing with Uncle Joe at the dinner table, we’ll show you how to pull apart a scientific headline using a friendly, practical checklist anyone can learn. Along the way we stress-test the study’s claims, take a quick detour into what a .04% buzz actually looks like, and run our own before-and-after experiment with two brave science journalists at the ScienceWriters2025 conference in Chicago. A holiday survival guide with vodka tonics, statistical sleuthing, and a few surprisingly smooth French phrases.

Statistical topics

  • Alternative explanations
  • Arithmetic consistency / GRIM test
  • Blinding
  • Effect size / magnitude
  • Generalizability / external validity
  • Observational studies vs. experiments
  • Outcome measurement
  • PICOT framework
  • Placebo and expectancy effects
  • Primary outcomes / pre-specification
  • Randomized controlled trials
  • Research hypotheses
  • Sample size 
  • SMART framework
  • Statistical significance (signal vs. noise)
  • Transparency and trustworthiness


Methodological morals

  • “​​You don't need a PhD to read a study. Just remember, PICOT and SMART.”
  • “A decimal point can mean the difference between life and death. Details matter.”

References



Kristin and Regina’s online courses: 

Demystifying Data: A Modern Approach to Statistical Understanding  

Clinical Trials: Design, Strategy, and Analysis 

Medical Statistics Certificate Program  

Writing in the Sciences 

Epidemiology and Clinical Research Graduate Certificate Program 

Programs that we teach in:

Epidemiology and Clinical Research Graduate Certificate Program 


Find us on:

Kristin -  LinkedIn & Twitter/X

Regina - LinkedIn & ReginaNuzzo.com

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