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November 18, 2025 6 mins

For conscientious pet parents and pet owners, understanding the reality of leaky gut syndrome in dogs is critical to solving chronic health issues. Dr. Randy Aronson and Olivia Sacci dive deep into this often-misunderstood condition, explaining exactly what leaky gut is, why it's actually the root cause of problems like allergies, GI disease, behavioral issues, and even cancer, and how it allows harmful substances into your dog's system.

In this episode of Paws, Reflect & Heal, Dr. Randy challenges the conventional veterinary approach to GI issues, warning pet owners against the common use of the antibiotic Metronidazole for leaky gut syndrome. He outlines a comprehensive integrative strategy focused on reducing inflammation through diet and targeted supplements. Discover why comprehensive allergy testing is the first step, the specific type of anti-inflammatory omega-3 you should be using (and why common fish oil is often counterproductive), how B12 helps with SIBO, and the surprising environmental trigger that is showing up in pets even in dry climates: household mold. 
#LeakyGutInDogs  #HolisticPetCare  #PetAllergies  #DrRandyPetVet 

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Episode Transcript

Available transcripts are automatically generated. Complete accuracy is not guaranteed.
SPEAKER_00 (00:08):
Dr.
Randy here with my co-hostOlivia Sache from the University
of Arizona Vet School.

SPEAKER_01 (00:13):
Hi everyone, it's good to be back.

SPEAKER_00 (00:14):
Hey Olivia, nice to have you here.
So we're going to answer aquestion from Elena in Florida
about leaky gut syndrome.

SPEAKER_01 (00:22):
Perfect.

Our question today is (00:22):
what is leaky gut syndrome in our dogs?

SPEAKER_00 (00:26):
Leaky gut is a very, very important thing for us to
know about in our dogs and cats.
It's not uncommon, and it isactually the cause of a lot of
problems that we see withallergy, with GI disease, even
cancer, and believe it or not,behavioral problems.

SPEAKER_01 (00:43):
I would know.
My dog has it and you helped,you helped treat it.
So what are some of thesupplements or treatments for
leaky gut syndrome?

SPEAKER_00 (00:51):
You know, before we do that, let me just mention so
leaky gut basically means thatthe small interfaces in our
bowel open up and allow thingsinto our system through the
blood and lymphatics that weshould not be incorporating.
So our dogs and cats are eatingthings that basically get into
their bloodstream or theirlymphatics and then causes the

(01:14):
signs that we see, whether it isallergy, whether it is GI
disease.
So let's go back to yourquestion, which was me not
hitting the microphone, buttalking about supplements.

SPEAKER_01 (01:24):
Yeah.
So I'm just curious, what can wedo to help our dogs that have
Lehiga syndrome?
Is there diets that we can givethem?
Are there supplements,medications?
What do you recommend?

SPEAKER_00 (01:33):
Absolutely.
So uh diet and supplements arereally, really important.
I try to stay away from themedication.
Um, I will mention onemedication that is my real pet
peeve, and that is using thedrug metronidazole.
Metronidazole is oftenprescribed for leaky gut
syndrome.
It does help with the GI signs,but it is an antibiotic that was

(01:55):
created to eliminate allbacteria in our bowel.

SPEAKER_01 (01:58):
So it's gonna kill the good things too, right?

SPEAKER_00 (02:00):
Absolutely.
And there are numerous papersthat are now out saying that
veterinarians really should notbe using metronidazole.
So let's talk about thesupplements and the diet.
So the way I approach this is umI do do a lot of times uh work
on an allergy testing typesituation for our dogs and cats.
It can be a IGA uh test calledNutriscan, which our our

(02:23):
listeners can get online uh fromNutriscan.
It's some swabs that they willthen be able to talk about what
the dog or cat's foodsensitivity is.
Or it could be a blood test,which is even more
comprehensive.
I use VDI labs and it's anallergy test that will tell us
exactly what foods andenvironmental allergens are
causing them a problem.

SPEAKER_01 (02:43):
So, how does eliminating the allergens help
with the leaky gut syndrome?

SPEAKER_00 (02:47):
That's a great question.
So it's all about inflammation.
We've talked about that before,but inflammation is the rooted
this.
If we can get the inflammationdown in our dog and cat's body,
we can get rid of the leaky gutsyndrome.
So then what happens is throughthese testings, we now pick a
food that we know we're notgonna have a problem with.
And we also make sure in ourallergy testing that there's

(03:08):
nothing environmental.
I will tell you, one of thescary things about the last
allergy test I've done here inTucson is multiple animals
showing up with a moldsensitivity.

SPEAKER_01 (03:18):
I've been in a couple of those cases with you.
Right.
Yeah.

SPEAKER_00 (03:20):
And then what happens is we tell the owners,
well, you know, this is Tucson,it's the most dry place in the
world.
Go test your house, and everyone of them have had mold in
their house.

SPEAKER_01 (03:29):
I remember you telling me that, and I was
shocked by that information.

SPEAKER_00 (03:32):
So getting to the supplements so we don't forget
those.
Um, I like omega-3s because Ireally want a source of
anti-inflammatory moistening forthe gut.
I use an omega-3 and not a purefish oil because fish oils are
omega-3, six, and nine omegas,and nines are inflammatory.

SPEAKER_01 (03:51):
So we want to- That's great information to
have.

SPEAKER_00 (03:53):
So we want to use an omega-3, preferably in a capsule
that people are pinpricking.
Why?
Because in a bottled oil, assoon as you pump down or open
oxygen gets in there and it doesstart to oxidize that oil.

SPEAKER_01 (04:05):
And once we oxidize it, it's not as effective
anymore.

SPEAKER_00 (04:07):
It causes the animal to have to form what's called
free radicals to scavenger thatoxidized oil.
Okay.
Second is a lot of times I'lluse uh methylcobalamine or B12.
B12 is really uh helpful for Suh SIBO, SIBO, small intestinal
bacterial overgrowth, which ispart of this whole syndrome, and
it really, really helps theirbowel.

SPEAKER_01 (04:29):
So in leaky gut, they're also having an
overgrowth of certain bacteria.
Absolutely.
Absolutely.
Okay, interesting.
And how does that happen?

SPEAKER_00 (04:36):
Well, what happens is um the bad bacteria are kind
of selected for, whether it'sfrom their diet of too many
inflammatory carbs in the dietor the wrong food, uh, and that
continues to grow.
Also, a lot of these animalshave been on antibiotics.

SPEAKER_01 (04:52):
Like the metronitizolesol.

SPEAKER_00 (04:53):
Like the metronitazol we talked about,
and that really selects for thethe some of the harder bacteria
to get under control.

SPEAKER_01 (05:01):
And what Dr.
Randy means by select isbasically if you if you give an
antibiotic, it's gonna kill offas much as possible, but it's
only gonna leave the strongestbehind.
And so that's what the termselect means, just for people
out there that maybe don't knowthat.
Very good.
But that can be that can bereally scary if you're only
leaving the strongest microbesback.

SPEAKER_00 (05:17):
Right.
We also incorporate slipperyelm.
We also incorporate turmeric,all very helpful.
But also another really bigthing before we close is fiber.
We really want to increase thefiber in our pet's diet, either
using psyllium husk or inulinwith pumpkin or sweet potato.
Uh, that's the best way to get alot of these under control.

SPEAKER_01 (05:37):
Perfect.
Well, thank you guys for joiningus.
Thank you, Dr.
Randy, for all of that insight.

SPEAKER_00 (05:41):
And you, Olivia.

SPEAKER_01 (05:42):
Thank you.
I'm so happy to be here.
Um, you guys can follow us bothon social media for Dr.
Randy.
He's got a YouTube channel aswell as an Instagram account.
You can find him at at Dr.
Randy PetFet.
For myself, I have an Instagramat at Dr.
Saatchi.
Saatchi is S-A-C-C-I.
Um, thank you so much.
Please subscribe.
You'll get information everyweek on how to help your pets.

SPEAKER_00 (06:02):
And let your pet parents and guardian friends
know about this information, themore the merrier when it comes
to getting this information out.
Thanks for joining us.

SPEAKER_01 (06:11):
Thank you.
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