Petri Dish

Petri Dish

Profane, insane, and 100% primo science, Petri Dish is a no-BS podcast that explores the wildest subjects in modern science with clarity and evil joy. Hosted by Sean Allen, a Nanoparticle/Immunology Researcher, and Nathan Allen, his "screenwriter" brother, Petri Dish fuses hard science with a freewheeling and madcap conversational style. Cannabinoids, Plague, Cats, the dreaded Candiru, and the even more dreaded Covid-19: all these and more are dissected with intellect and irreverence, dropping every week. So reject ignorance. Join the Scientific Revolution. Join Petri Dish.

Episodes

October 11, 2021 40 min

Welcome to part 3 of our series on HIV/AIDS! In the previous two episodes we covered the history of HIV/AIDS and how HIV/AIDS works on the cellular level. In this episode we use that information to understand how our current arsenal of anti-retroviral drugs work! Next week we'll be discussing the treatments on the horizon that may help us reach an end of the HIV/AIDS global epidemic!

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This week on Petri Dish we dive deeper into HIV/AIDS pathophysiology -- how does HIV do what it does to your body? How does the virus target specific cells? What does it do once it gets into your cells? Definitely an important episode to listen to in order to prep for our next two episodes on current and future treatments!

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September 27, 2021 33 min

Recent news has led to a lot of excitement with relation to HIV/AIDS -- approval for clinical trials using a new vaccine and a new treatment/potential cure has led to a lot of buzz! But what is the current state of the HIV/AIDS global epidemic? When did HIV first evolve into being? What even is HIV?

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September 20, 2021 26 min

This week we have a short episode, a Q&A on COVID vaccine booster shots based on the latest info from 09/17/2021! Who can currently get a COVID booster shot? What happened with the FDA recently relating to booster shots? What even is a booster shot? Find out this week!

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It's part 2 of our collaboration with The Microbe Moment (a podcast from The Microbigals! https://www.microbigals.com/the-microbe-moment-science-podcast)!

We return to our discussion of some of the more ridiculous Medieval treatments for diseases that we could find in our research! Listen in for some of the odder things humans have done to other humans to try to treat a disease!

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In the first episode of our collaboration with The Microbe Moment (a podcast from The Microbigals! https://www.microbigals.com/the-microbe-moment-science-podcast), we discuss some of the more ridiculous Medieval treatments for diseases that we could find in our research! Listen in for some of the odder things humans have done to other humans to try to treat a disease!

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In this final episode of our series on Multiple Sclerosis, we discuss the current treatments available for the disease, mainly for the relapsing/remitting form. We then discuss what some of the future treatments look like, including those currently in clinical trials, that may be able to help treat the progressive form of MS!

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Last week we started our series on multiple sclerosis by discussing the history of the disease, the symptoms, and the various forms of the disease. This week we dive into the biological cause of the disease. What makes multiple sclerosis pop up? What sorts of genetic or environmental factors seem to play a role?

We also recommend you check out Eps 63/64 on the blood brain barrier, Eps 56/57 on autoimmune disorders, and Ep 38 on the...

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In this week's episode, Nathan and Sean start their discussion of multiple sclerosis, a progressive autoimmune neurodegenerative disorder with a ton of symptoms and freaky way of popping up and disappearing willy-nilly! Learn about Saint Ludwina, the patron saint of ice skaters! Find out what myelin is! Hear acronyms like RRMS! All on this week's episode of Petri Dish!

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This week on Petri Dish, Sean, Nathan, and special guest Andrei wrap up their discussion on non-nutritive sweeteners by looking at what evidence is out there on potential harmful impacts of these sweeteners. Do sweeteners cause cancer? Do they help you lose weight, or actually make you gain weight!? What about your microbiome, or the environment? Find out this week!

References:

  • https://www.sciencedirect.com/science/article/pii/S092...
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    Hey everyone! This week's episode continues our discussion on non-nutritive sweeteners! Last week we discussed synthetic sweeteners, the ones made in labs like Sweet N Low or Splenda. But there are sweeteners on the market that are 'natural', like stevia or monkfruit. What is up with those sweeteners? Are they just different kinds of sugars, or are they something else entirely?

    References:

  • https://www.mdpi.com/2072-6643...
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    This first episode in our three-parter on non-nutritive sweeteners is about the artificial stuff, the most-accidental discoveries that led to saccharin, aspartame, sucralose, all the big ones, all the hits! How do these synthetic sweeteners work? How do they differ from one another?

    Next week we'll cover 'natural' non-nutritive sweeteners and the week after that we'll cover whether there are any risks to their frequ...

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    In this final episode of our series on Alzheimer's Disease, we discuss some of the alternate hypotheses for what actually causes and drives progression of Alzheimer's Disease, if not amyloid beta. What other ideas are some scientists working through?

    Featuring a promo for Infectious Groove, a great podcast music podcast!

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    References:

  • https://pubmed.ncbi.nlm.nih.gov/29663818...
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    I don't know if y'all have heard or not, but a month ago the FDA approved a drug for the treatment of Alzheimer's Disease, the first one in a couple of decades. This approval was met with the resignation of some members of the FDA's own scientific advisory group, which had recommended that the drug not be approved. What is going on here? Let's get into the science behind this drug, how the approval process works...

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    One of the top killers of people over the age of 65, Alzheimer's Disease is the target of cutting edge pharmaceutical research and basic science. What do we already know about the symptoms and their biological causes? As it turns out, there is still a good amount of controversy when it comes to the fundamental mechanism of this disease!

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    References:

    https://www.nia.nih.gov/heal...

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    Last week we discussed how someone could go about cloning something, but this week we dive into the WHY. Maybe there is no particularly good reason to do reproductive cloning for humans, but what about individuals of endangered species? What about trying to bring back recently extinct species? What about cloning to try to create new species?

    Featuring a promo for The Bald Scientis...

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    June 21, 2021 35 min

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    Jurassic Park! Dolly the Sheep! Mammoths! Cloning went from science fiction to science, but maybe had fallen a bit out of vogue for a while? But some other concepts that can include cloning technology, like certain kinds of stem cell work and maybe bringing extinct species back to life! This episode, find out how reproductive cloning works! Next episode we'll talk about what i...

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    Back from the brief interruption of our allergies series to celebrate our 100th episode, we're wrapping things up by talking about treatments for allergies and what scientists have been cooking up to help people get back to snorting cat dander. Don't worry, only one of the treatments involves getting purposefully infected with worms.

    Feat. a promo for Oz-9, a very funny sc...

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    June 7, 2021 51 min

    The 100th episode! Woo, we did it everyone! Thank you for listening to the podcast! This episode, Sean released his grip on the reins and let Nathan and Stacey pick topics to discuss, and so this episode is about:

    The History of the Number Zero

    Buttholes (Thanks, Nathan)

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    Featuring a promo for Curiosity Kill the Rat, another great science podcast!

    References:

  • https://psycnet.apa.or...
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    Okay, so you have allergies, your friends have allergies, your enemies have allergies -- why does everyone seem to be allergic to stuff nowadays? Are we more allergic to things than we used to be? And if so, why?

    PROMO: Plants and Pipettes Podcast!

    References:

  • https://link.springer.com/article/10.1007/s00281-020-00785-1
  • https://www.nature.com/articles/nri.2017.39.pdf?o...
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