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November 21, 2025 18 mins

Jeff Bezos is officially back in an operational role — and he’s betting billions on a new AI venture called Project Prometheus. But this isn’t another chatbot startup. This is AI aimed squarely at the physical economy: manufacturing, materials, engineering, aerospace, supply chain, and the real-world systems that make global industries run. 

In this episode, Gary and Scott break down: 
• What Project Prometheus is — and what we actually know so far 
• Why it’s attracting elite talent from OpenAI, DeepMind, and Meta 
• The meaning of “AI for the physical economy,” explained in simple terms 
• How Bezos and co-leader Vik Bajaj are positioning this as a multi-decade moonshot 
• The emerging shift from digital AI to AI that designs, builds, and optimizes physical systems 
• Potential applications: factories that self-optimize, AI-designed materials, robotic labs, new aerospace components, and more 
• The profound implications for business leaders across manufacturing, engineering, logistics, and operations 
• The risks, unknowns, and why Prometheus could reshape competitive advantage for entire industries 

This is one of the clearest signals yet that AI is moving beyond screens and into the world of atoms. If you’re a CIO, COO, CTO, or executive responsible for operations or innovation, this episode will give you a front-row view into the next wave of AI transformation — and what you should be watching now. 

Listen in and learn why the future of AI won’t just be about thinking… it’ll be about building. 

Send a Text to the AI Guides on the show!


About your AI Guides

Gary Sloper

https://www.linkedin.com/in/gsloper/


Scott Bryan

https://www.linkedin.com/in/scottjbryan/

Macro AI Website:

https://www.macroaipodcast.com/

Macro AI LinkedIn Page:

https://www.linkedin.com/company/macro-ai-podcast/


Gary's Free AI Readiness Assessment:

https://macronetservices.com/events/the-comprehensive-guide-to-ai-readiness


Scott's Content & Blog

https://www.macronomics.ai/blog





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