Could one of the most effective ways to boost survival after a colon cancer diagnosis be exercise? In this episode, I dive deep into the groundbreaking CHALLENGE Trial, a landmark study that explored how a structured exercise program impacts survival rates for colon cancer patients. We'll break down the study's surprising results, including a 28% relative reduction in disease-free survival events and a 37% relative reduction in the risk of death, and discuss what this could mean for the future of cancer care.
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CHAPTERS:
00:00 - Intro
00:34 - Old Evidence
01:40 - CHALLENGE Trial Intro
02:51 - Population, Invervention, Comparators, Outcomes
04:30 - Healthier Survivor Problem
05:22 - No True “Control” Group
06:55 - Main Results
08:08 - Fitness Outcomes
10:01 - Safety and Side Effects
11:07 - What Explains These Results?
12:03 - Comparing These Results With Older Results
13:27 - New Standard of Care?
15:03 - Future Areas of Research
16:11 - My Takeaways
17:50 - Outro
SELECTED REFERENCES:
https://www.nejm.org/doi/full/10.1056/NEJMoa2502760
*Disclaimer* This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.
colon cancer, exercise, cancer survival, CHALLENGE Trial, oncology, cancer research, disease-free survival, structured exercise program, physical activity, cancer treatment, cancer care, evidence-based medicine
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