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September 9, 2026 โ€ข 18 mins

Why does progesterone help one woman sleep, feel calm, and finally feel like herself again—while another woman feels anxious, restless, or completely unlike herself?

The answer may have a lot to do with how progesterone enters the body and what it becomes after you take it.

In Part 11 of this progesterone series, Dr. Brendan McCarthy breaks down why the route of administration matters when using bioidentical oral micronized progesterone. Oral, transvaginal, transrectal, topical, and sublingual routes can influence how progesterone is metabolized and where its effects are felt.

๐Ÿ“š Patient Education: Explore our patient education resources here: https://protealife.com/patient-education

โš ๏ธ This podcast is for educational purposes only and is not a substitute for individualized medical advice. Do not abruptly change or stop hormone therapy based on information you hear online. Talk with your healthcare provider about your specific situation.

Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more.

If you’re ready to take your health seriously, this podcast is a great place to start.

๐Ÿ‘‡ Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it.

๐Ÿ“˜ Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-...

๐Ÿ“ฒ Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com

๐Ÿ’ฌ Got a question or topic for a future episode? Let us know in the comments! 

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