Episode Transcript
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Speaker 1 (00:00):
Welcome back to Navigating a Zepic, the podcast where we
illuminate the most recent news controversies, medical breakthroughs, and community
experiences surrounding a zenpic and related semaglutide medications. It is Saturday,
November eighth, twenty twenty five, and in today's episode, we
are diving deep into the newest developments from the past
(00:21):
seventy two hours. There's a lot happening in a world
of a zempic this week, so let's get right into it. First,
let's cover the most urgent updates from ongoing litigation. According
to the Lawsuit Information Center, the ozempic multi district litigation
now has over two thy nine hundred cases pending, highlighting
just how widespread and complex the legal challenges have become.
(00:43):
In just the past few days, a new lawsuit was
filed by a woman in California who alleges she suffered severe,
potentially permanent gastro intestinal injuries specifically ilius and gastroparesis, after
starting weigovi in mid twenty twenty three. She cleaned the
symptoms forced her off the drug, led to significant pain, vomiting,
and emergency medical intervention, and argues that the manufacturer Novo
(01:06):
Nordisk failed to adequately warn both consumers and doctors about
these risks. The complaint also contends that the aggressive marketing
of weagov as a miracle weight loss solution downplayed these
very real dangers. As this trend unfolds, legal experts anticipate
the case will serve as a bell weather for future
suits regarding serious gastor intestinal complications. Since September, the litigation
(01:31):
focus has notably shifted. Plaintiff's attorneys originally faced difficulty proving
that ozempic induced gastroparaesis was distinct from complications related to
diabetes itself. That landscape changed in August last year, when
the European Medicines Agency ordered updated warning labels for ozempic
and similar drugs to highlight the risk of a rare
(01:52):
but grave eye condition, non arteritic anterior ischemic optic neuropathy
NAAANTA nation causes inconceivable, n often irreversible vision loss, usually
in one eye. The regulatory action provided fresh ammunition for
attorneys representing those who say ozepic ravaged their site without
(02:14):
sufficient warning, a story now picking up steam in federal
and state courts. A prime example comes out of Texas,
where a recent lawsuit alleges a fifty two year old
woman went blind in one eye after just six months
of ozepic use. Her legal team is arguing Novo Nordisk
ignored early warning signs from clinical trials and failed to
alert doctors or patients to the mounting risks. Similarly, a
(02:38):
large scale analysis from the University of Toronto published in
Jamma off Thermology followed merely one hundred and forty thousand
people with type two diabetes and found that those on semaglutide,
the active ingredient in ozempic and wegovi, were twice as
likely to develop neovascular age related macular degeneration, another condition
(02:58):
linked to vision impairment. The increase was relatively modest in
absolute terms, about two cases per thousand compared to one
per thousand in non users, but the statistical link was clear.
Researchers theorize that semaglutide's effects on vascular and inflammatory pathways
may trigger disease, and the results add another layer of
(03:19):
complexity to ongoing litigation over vision loss. Some of these
legal strategies are now being formalized. Just as September, attorneys
in the Ozepic Multi District Litigation propose the creation of
a formal vision injury track to streamline cases tied to
nai in and other ocular problems. At present, more than
(03:40):
one hundred and forty cases under their MDL involve claims
of partial or complete blindness, and lawyers hope this move
will help consolidate evidence and expert testimony while accelerating the
judicial process. The defense has yet to respond, but what
as clear as this, lawyers are tightening their focus, and
vision lawsuits have moved from the background to the very
(04:03):
center of this legal storm. On the regulatory side, just
last week, fair Nuts United States Food and Drug Administration
announced the new green list of approved overseas suppliers for
compounders making summer glutide drugs, including both Ozempi and wegov.
This is a reaction to surging demand, which earlier led
(04:23):
to a flood of unregulated and potentially unsafe compounded medications
in the United States market. While it is a positive
step for drug safety, both Nova Nordisk and Eli Lilly
saw immediate market impact, with their stocks falling on the
day of the announcement. Meanwhile, another story continues to gather steam.
The relationship between ozepic and various forms of cancer. A
(04:46):
January article from drug Watch highlights a study linking the
use of GLP one receptor agonists to arise in fireroid
cancer diagnoses. The study, analyzing more than three hundred and
fifty thousand adults with type two diabetes, found those starting
on these drugs, including a zenpic and Monjaro, had significantly
higher rates of thyroid cancer in the first year compared
(05:08):
to those on other diabetes medications. Researchers admit the increase
may partly stem from heightened surveillance rather than a direct
cancer causing effect, but the findings have intensified scrutiny over
the drug's broader saety profile. Turning to a Zenpic's medical
benefits and expanding uses, the news is not all negative.
In September, the Food and Drug Administration approved a new
(05:31):
use for Wagovi semaglutide's higher dose form as the first
medication for treating metabolic dysfunction associated steto hepatitis, a serious
fatty liver disease affecting those with moderate or advanced liver scoring.
International studies are showing that eleven months of semaglutide use
can shrink liver information in sixty four percent of patients
(05:52):
and improve or even reverse fibrosis in more than a third.
Given the prevalence and severity of fatty liver disease, this
is a potent, actually life saving indication, particularly for patients
with limited other options. There are also emerging findings around
kidney disease. Earlier this year, the Food and Drug Administration
approved ozebic as the only GLP one me