MDS Podcast

MDS Podcast

Stay up to date on novel, clinically-relevant research findings in Parkinson's disease and other movement disorders. Each episode of the International Parkinson and Movement Disorder Society podcast discusses a relevant development in the field, including highlighted journal articles and interviews with the authors.

Episodes

Prodromal autonomic dysfunction in Lewy body diseases

May 18, 2026
Prodromal autonomic dysfunction has emerged as an important area of research in understanding Lewy body diseases, including Parkinson's disease, and dementia with Lewy bodies. Dr. Michelle Matarazzo sits down with three experts in the field, Dr. Abhimanyu Mahajan, Dr. Alison Yarnall, and Dr. David Goldstein to discuss the current evidence behind various disturbances and how they may precede classic motor and cognitive symptoms, suc...
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Ataxia Series: Beyond the cerebellum - Non-motor features and multisystem care in genetic ataxias

May 11, 2026
Genetic ataxias have many non-motor features, such as fatigue, sleep disorders, and cognitive dysfunction. In this episode, Dr. Orlando Barsottini and Dr. Christofer Stephen discuss the most common non-motor symptoms and how to approach them.
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Modulating the peripheral immune response: LRRK2 and GBA1 mutations

May 4, 2026
Dr. Michele Matarazzo sits down with Dr. Rebecca Wallings to discuss  how two of the most important genetic forms for Parkinson's disease, LRRK2 and GBA1, influence immune response to bacterial simulation. Their discussion highlights a potential link between genetics, environment, and inflammation in Parkinson’s disease. Journal CME is available until March 18, 2027
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Ataxia Series: Neuroimaging patterns not to miss in ataxia

April 27, 2026
In this episode, Dr. Orlando Barsottini and Dr. Malco Rossi discuss the main imaging findings and clues for the the diagnosis of genetic and sporadic ataxias.
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What is it? A young boy with deafness and twisting limb movements

April 20, 2026
In this episode Dr. Hugo Morales Briceno and Dr. Ai Huey Tan discuss how to approach deafness-dystonia syndrome and its etiological differential diagnoses. Read the discussed case.
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Ataxia Series: Recognizing sporadic ataxias

April 13, 2026
In this interview, Dr. Orlando Barsottini and Dr. Divyani Garg discuss the main forms of sporadic ataxias, how to approach them, and what steps not to miss.
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History of Movement Disoders: The influence of videography

April 6, 2026
Dr. Mattia Rosso joins Dr. Sara Schaefer to discuss the historical use of videography in movement disorder clinical practice and education, and how it influenced the evolution of the field. Read the article.
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Ataxia Series: Deconstructing late-onset idiopathic ataxia

March 30, 2026
Cases of late-onset cerebellar ataxias are a challenge for neurologists. In this episode Dr. Orlando Barsottini and Dr. José Luiz Pedroso discuss new advances on the investigation of late-onset cerebellar ataxias and identification of new genes.
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Rethinking Parkinson’s: The Somato-Cognitive Action Network (SCAN) hypothesis

March 23, 2026
Dr. Michele Matarazzo interviews Prof. Hesheng Liu about his recent Nature paper proposing a major conceptual shift: Parkinson’s disease as a somato-cognitive action network (SCAN) disorder. Together they discuss how a large multimodal dataset suggests a characteristic pattern of hyperconnectivity between SCAN cortical areas and subcortical nuclei in Parkinson’s disease, how this signature changes with effective therapies, and why ...
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Ataxia Series: The ataxia exam - Phenomenology, classification, and a practical diagnostic roadmap

March 16, 2026
In this episode, Dr. Orlando Barsottini and Dr. Bart van de Warrenburg discuss the importance of precise neurological examination and classification of ataxias. The further discuss the rational etiological investigation for cases of ataxia and how to utilize different clinical assessments.
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Long-Term Follow-Up of Patients with Mass Social Media-Induced Illness Presenting with Functional Tic-like Behaviors

March 9, 2026
In this episode, Dr. Kirsten Müller-Vahl explores one of the first long-term follow-up studies of mass social media–induced functional tic-like behaviors (MSMI-FTLB). She discusses what their findings mean for clinical counseling, why early diagnosis appears to improve outcomes, how factors such as psychiatric comorbidity and secondary gain influence recovery. She also examines the surprising finding that reduced screen time did no...
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Revisiting the 2015 MDS clinical diagnostic criteria for Parkinson's disease

March 2, 2026
Dr. Eduardo de Pablo-Fernández is joined by Dr. Susan Fox and Dr. Claudia Trenkwalder to discuss how to improve the current MDS clinical diagnostic criteria for Parkinson's disease. Read the article.
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Distinguishing functional from idiopathic dystonia: A novel approach

February 23, 2026
Functional dystonia can closely mimic idiopathic dystonia, and objective physiological markers to support the diagnosis are still limited. In this episode, Dr. Michele Matarazzo speaks with Prof. Roberto Eleopra about a pilot study using poly-EMG during a controlled propofol sedation protocol to help differentiate functional from idiopathic dystonia. They discuss the study’s rationale and design, the key findings, and what this app...
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What is it? Exercise-induced episodic gait disorder in a young boy

February 16, 2026
A young boy presents with exercise-induced episodic gait disturbance. Dr. Shekeeb Mohammad analyses the clinical phenomenology alongside laboratory and neuroimaging findings, systematically exploring the differential diagnosis before arriving at the final diagnosis.
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CSF proenkephalin as a biomarker for premotor Huntington's disease

February 9, 2026
Dr. Mena Farag joins Dr. Eduardo de Pablo-Fernández to discuss how proenkephalin and other biomarkers can help monitor the earliest stages of Huntington's disease decades before the onset of motor symptoms. Journal CME is available until February 11, 2027
Read the article.
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Shame in Parkinson's disease: An unseen burden

February 2, 2026
This episode explores shame as an often-overlooked but impactful non-motor symptom of Parkinson’s disease. Drawing on her team's recent research, Dr. Vanessa Fleury discusses the psychological and clinical determinants of shame, its strong link to quality of life, and why it deserves greater attention in routine care. The conversation highlights how recognizing and addressing shame may open new avenues for more holistic, patient-ce...
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Pregnancy and Parkinson’s disease: Navigating care before, during, and after

January 26, 2026
In this episode, Dr. Alexander Lehn explores the clinical management of Parkinson’s disease across the reproductive journey; before conception, during pregnancy, and in the postpartum period. He shares the current evidence, practical challenges, medication safety considerations, and multidisciplinary decision-making. The conversation highlights gaps in data, real-world clinical strategies, and key counseling points to support optim...
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Effects of a probiotic on Parkinson's disease symptoms

January 19, 2026
Dr. Sara Schaefer is joined by Dr. Valentina Leta and Dr. Ray Chaudhuri to discuss their randomized controlled trial on the effects of probiotic use on inflammation, motor, and non-motor symptoms in Parkinson's disease. Journal CME is available until December 18, 2026
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History of Movement Disorders: Jean-Martin Charcot

January 12, 2026
In another installment of the ongoing History Series, Dr. Christopher Goetz joins Dr. Sara Schaefer to discuss the legacy of Jean-Martin Charcot within the fields of medicine medicine, neurology, medical education, and movement disorders.
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Hot Topic: Integrating palliative care into routine care for patients with movement disorders

December 22, 2025
Dr. Sarah Camargos continues her conversation on palliative in movement disorders by interviewing Mr. Victor McConvey. Together they discuss the current state of palliative care in movement disorders including current barriers, challenges, and future goals.
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