The Skin Real ®

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Dr. Mary Alice Mina sits down with oral and maxillofacial surgeon Dr. Erin Sheffield to explore a part of facial aging most people never think about: the mouth. They dig into why tooth loss drives bone loss in the jaw, why flossing (done correctly) is one of the highest-impact, lowest-cost things anyone can do for their whole-body health, and why...

In this episode, Dr. Mary Alice Mina answers the internet's most asked questions about testosterone, topical estrogen, and perimenopause. Pulled straight from the comments section, she covers who can actually prescribe testosterone, whether estradiol and estriol can be used together on the face, what swollen eyelids might really mean, what lab work matters before starting testosterone therapy, how topical estrogen interacts with bi...

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Filler has had its moment, and for years the look was to go bigger: fuller lips, bigger cheeks, an almost caricature version of the face. Dr. Mary Alice Mina breaks down why the pendulum is swinging back toward natural results and what that means for anyone rethinking their filler. She walks through what hyaluronic acid filler actually is, how it...

Head lice might be one of the most stomach-turning phrases a parent can hear, but Dr. Mary Alice Mina wants everyone to take a breath before reaching for the clippers. In this episode of The Skin Real, she breaks down what head lice actually are, why they have nothing to do with hygiene, and how they really spread through close head-to-head contact rather than jumping from scalp to scalp. She walks through exactly how to check for ...

In this episode of The Skin Real, Dr. Mary Alice Mina sits down with dermatologist and Skinfluence Podcast host Dr. Dustin Portela to break down the skincare trends flooding social media right now. From DIY sunscreen and beef tallow moisturizer to at-home chemical peels and tanmaxxing, they separate real dermatology from viral misinformation. The conversation covers red flags to watch for in skincare influencers, the science behind...

Basal cell carcinoma is the most common cancer on the planet, yet most people have never heard of it until they're sitting in a dermatologist's chair hearing the word cancer for the first time. In this episode, Dr. Mary Alice Mina walks through what these lesions actually look like, and it's rarely what people expect. Sometimes it's a pink, shiny bump that...

Exosomes are one of the most talked about ingredients in skincare right now, but most people buying them have no idea what they are actually paying for. In this episode, Dr. Mary Alice Mina sits down with Alisa Lask, CEO of Rion Aesthetics and lead of Plated Skin Science, to break down what exosomes really are, why the source they come from matters more than the word on the label, and how platelet-derived exosomes differ from plant...

In Part 2 of this mini series on Collagen Loss, Dr. Mary Alice Mina moves from biology to action: the exact morning and evening skincare routine that makes sense for post-menopausal skin, which ingredients actually have evidence behind them, and which in-office treatments are worth the money. She walks through why a routine built for oily 20-something skin works against you later, then breaks down a simple AM routine (gentle cleans...

In the first half of a two-part episode on midlife skin, Dr. Mary Alice Mina breaks down the biology behind one of the most alarming stats in dermatology: women can lose up to 30% of their skin's collagen in the first five years after menopause. She explains why collagen decline actually starts as early as your 20s (about 1% a year), why estrogen loss accelerates that process dramatically at menopause, and why "collagen banking" ea...

In this episode of The Skin Real, Dr. Mary Alice Mina sits down with fellow board-certified dermatologist Dr. Amaris Geisler, a specialist in vulvar dermatoses based in Atlanta, to break the silence around a body part most women can't even name correctly — the vulva. They cover what the vulva actually is (versus the vagina), the most common conditions dermatologists see there (lichen sclerosis, eczema, psoriasis, and even ski...

Salmon sperm in your skincare? It sounds wild, but PDRN (polydeoxyribonucleotide) is everywhere right now — on your For You page, in Korean skincare hauls, and yes, Kim Kardashian had it injected into her face. In this episode, Dr. Mary Alice Mina cuts through the hype and gives you the full, unfiltered picture on what PDRN actually is, where it comes from, an...

Fungal acne is everywhere on social media, but most people are treating it completely wrong. In this episode of The Skin Real, Dr. Mary Alice Mina breaks down what fungal acne actually is: an overgrowth of malassezia yeast, not bacteria, and not true acne at all. She explains why standard acne treatments often fail, who's most at risk (think sweaty workouts, humid climates, tight clothing, and recent antibiotic use), and how to tel...

Sunscreen is the single most impactful thing you can do for your skin — and in this episode of The Skin Real, Dr. Mary Alice Mina breaks down exactly what to look for, what to skip, and which sunscreens she's personally stocking up on for summer 2026. Dr. Mina explains why UV radiation is responsible for the majority of premature aging and skin cancers, and why the U.S. has fallen behind the rest of the world in UV filter tec...

Your skincare routine might be missing its most important ingredient — and it's not in any bottle. In this episode of The Skin Real, Dr. Mary Alice Mina breaks down the powerful (and often overlooked) connection between protein and skin health. She explains the four root causes of skin aging — collagen depletion, chronic inflammation, oxidative stress, and cellular waste buildup — and why what's on your plate dire...

Topical estrogen is everywhere right now — but if you have melasma, rosacea, or acne, should you be worried? In this episode, Dr. Mary Alice Mina cuts through the fear-based noise and breaks down what the science actually says about topical estrogen and skin conditions like melasma and rosacea. She shares her own personal experience with melasma, explains why estrogen alone isn't enough to trigger it, and walks through what t...

In this episode of The Skin Real, Dr. Mary Alice Mina breaks down two of the most talked-about biostimulators in aesthetic medicine — Sculptra and Radiesse — and explains why they are not interchangeable, despite both building collagen. She covers how each product works at a cellular level, what to realistically expect after treatment (including the swelling that disappears in the first week), how long results last, whi...

Dr. Mary Alice Mina breaks down the top five tretinoin mistakes she sees her patients make — and admits she's made herself. From the dreaded purge to layering too many actives, she explains why so many people quit this powerhouse ingredient right before it starts working, and exactly how to use it correctly. She covers the difference between purging and irritation, the right amount to apply, how often to use it, why it's not ...

In this episode, Dr. Mary Alice Mina breaks down everything you need to know about your skin barrier — what it is, how you know it's damaged, and exactly what's causing the damage. She then walks through eight practical, zero-cost steps to repair it fast. From doing a hard skincare reset to applying moisturizer the right way, Dr. Mina cuts through the noise and reminds listeners that when it comes to a damaged skin barrier, l...

In this episode, Dr. Mary Alice Mina breaks down one of her most frequently asked questions: should you be putting topical estrogen on your face? She explains what estrogen loss actually does to the skin during perimenopause and menopause — from collagen collapse to barrier breakdown — and why these changes are hormonal, not just "normal aging." Dr. Mina walks through the two main forms of topical estrogen (estriol and ...