The text below is machine transcribed.
Welcome to Stuff You Should Know a production of iHeartRadio have stuff works, hey and welcome to the global nightmare. I'm Josh, there's chuck there's Jerry over there and we, our stuffyo shoul know, was that's an Alice Cooper Song Right.
That's welcome to my nightmare.
Oh, I think it is my nightmare. Isn't it yeah, but he should have thought bigger yeah.
He really should have. I was kind of she excited yeah.
Well put. We saw him in concert once member. That's right, big, shout out to Nitastraus. Yes, guitaristextraordinary for alise Cooper, among others, yeahiis enthusiast, what enthusiast science, Oh yeah, yeah for sure Soso! We should.
I think everyone knows right now that we are now set up to record apart from one another. Yes shuck.
So my first question before we have to get serious is what are you wearing? I knew it.
Can I tell you seriously what I'm wearing yeah I'm going to tell you?
Okay, I am wearing an apron and that's IT YEP wow yeah.
What about you?
So your cosplaying is sexy chef, yeah yeah! That's what I like to think of myself as it's not really Cosplaye. That's kind of normal life, stuff yeah I am wearing and this is not a plug, but it is what I'm wearing I'm wearing meandes.
I m. where I'm wearing my Mac Weldon, I don't know what they call him t you know kind of the warmup pant thy. You can go to the grocery store in sure, but do not go to the grocery store chuck. I Not Okay and I'm wearing a Max Fun Con, Two Thousand and twelve TSHIRT and my slippers.
So basically, this is your.
I got all this free outfit boy. It really is I paid for the slippers.
Okay, but I mean if you name, drop the slippers. Maybe you can get a replacement for him.
I don't want to do that. Even though they're super compny, maybe we can get a slipper sponsorship.
Did you did you ever stop wearing slippers out of the house?
Well, what do you mean?
So I think it was ou. Five second rule episode where we talked about the point of slippers is just have these things that are housebound and never leave your house, and then you, you just wear them in your house and instead of outside, so the outdoors germs never come inside on the bottom of your feet: Boy Tabs, you're, calling out Loike at nine year old episode.
I will you know I may go get the mail or something okay, all right well before you are going in like getting ice cream at the convenience store in those things. If I know what's that, yeah yeah and I feel like the fact that you're not doing anymore, you may have forgotten, but that's my influence, chuck my Ori Mate or I may have just gotten - gained some selfrespect right Er. You Go di like to think both of those fore. My influence, okay, yeah. So at the head of the show, I think we should announce we're doing an episode on covid nineteen.
It is Tuesday, I don't even know what date it is o cark of time March twenyi forth, and this will come out on the twenty six right.
That's what Jerry's promising right now that remains to be seen, though so it'll be sort of up to date, but two days a lot can change eras. We all know yeah and the other thing too is it.
I think we are going to stay out of sort of the politics and the economics of of this, because that's a almost separate podcast in itself that I have no interest in ever doing.
I well I'm surprised to hear you say that last part, I was figuring that that would be one we do like years from now like go back and look at the coronavirus pandemic of two thousand and twenty, because I think so many weird remarkable interesting things are going to grow out of this and are already going on.
I could totally see us doing that, but I get what I can vibe on what you're saying becauset after recording this HM, like I'm hoping that we can finish this episode and never talk about coronavirus again, like I get what you're saying that would be great yeah, I'm tired of knowing about it. You know yeah and we you know we debated quite honestly whether or not to even do this, but it seems like we had more people asking for just a level head to take on it from us than people saying I would really rather be distracted, so we'll distract you after today yeah and we're also, I mean we're not riding that wave where we're like trying to feed your news, addiction that, like you, can't get enough breaking information about this global pandemic, like, like, you said we're just trying to add just trying to do a stuff. You should know on coronavirus on covid nineteen specifically, and we got we got some big help, a big assist from Dave ruse who initially pushed back. We had to convince him to do it. Remember he's like you sure if people want to hear this yeah we're like yeah, we're pretty sure we'll find out, though so thanks a lot daverse. You did good and also a big shout out to the grabster to WHO's been under the weather, so hang in their grabster yeah. So let's, let's get going. I learned a lot in the last couple of days and the first kind of dumb thing that I learned was that covid nineteen stands for coronavirus disease, two thousand and nineteen, yes, which I didn't even know that until two days ago, is that right, yeah I mean it's not talked about a lot and I didn't bother to look it up so yeah and I guess it's not intuitive looking at it, if you think about it, but there's other names for it too, the WHO. So so, what you just said: Coronavirus disease, two thousand and nineteen covid nineteen. That's the name of the disease right, there's another name for the disease that the WHO calls two thousand and Nineteen Dsh in cove, okay and then the virus itself.
If you want to really show off at your next online dinner party, the virus itself is technically named SARS cove two Yeah Dash Big Sea little o big V, Dsh to that's right and, as we'll see the reason that it as called SARS cove to is because it bears a striking genetic resemblance to SARS cove one. I guess you could call it or the SARS the ars virus that that swept then swept the world not too long ago, too yeah, and I can't help every time I hear of SARS. I still the first thing I think of is the Saturday night live sketch with Peter SARS gard when he developed the SARS guard stars Gard Yeah. When did we talk about that before as it the virus's one or the Spanish flu episode?
Maybe I don't think we did one on SARS? Did we no not as far as I remember Huh, because because I don't know much about Coronavirusus wher, I didn't until we really started researching this, but that is what covid is it's a coronavirus and coronaviruses have been around for a while.
They are a family of viruses that typically cause upper respiratory infections in humans and chickens and pigs and cows coronaviruses, usually cause diarrhoea or intestinal infections, but in humans it's usually the upper respiratory tract. Although we have seen now that coronaviruses can cause pig or cawlike infections in humans to we've seen that recently, but but for the most part, you've probably been exposed to a coronavirus, you probably be made sick by one and normally coronaviruses just give us something that we would take as a cold or a common flu, yeah and Corona Means Crown, and both Spanish and Latin, and these images that you've seen the illustrations of what it looks like under a microscope, those little spikes protruding from the surface. Those are kind of what I guess, how it got its name as corona yeah Dave puts it here like it reminds him of pinhead from the hellrazor movies who, by the way, has a really good back story. I was reading about him, just ha by happens, dance the other day, an hat yeah he's a really interesting guy.
The whole reason he got into you know, being a Ceno byte in hell was he was disillusioned by the chaos of World War, one and lost, like all all faith in any meaning to life, so he started to he just ditched this world for hell. Instead, Oh wow, that didn't know that was a back story. Oh yeah, there's a bunch of itit's kind of been built up over the course of some of Clive barkers novels. The movies have contributed to it. Some other people have kind of contributed to it and there's like this robust kind of mythos around that guyit's really interesting stuff see. I am appreciating our sides more than ever today.
Yeah me too, it's kind of like do. We have to talk about this yeah. Let's talk more about movies. Have you seen the new candy man? That's coming?
Are they remaking candyman, yeah, Jordan, peels producing it O, and I saw a trailer, looks pretty good.
Did you like us?
I was UN.
I was not moved entirely by it. I really like get out a lot more than us, but I'm a fan of Jordan peal to think he's got a great mind and everything, but I don't know if I was expecting more from us or I was expecting something different, I'm not sure.
Well, I like to get out more for sure US got a little wacky, but then I I think I appreciate it more is like a sort of a twiylight, zonie kind of wacky yeah. I guess if I had gone into it, expecting that I think I would have liked it more yeah. I dug it great, acting too Oh yeah for sure across the board.
All right do we have to talk about this now, yeah back to it all right, so you said that chances are that at some point you might have had a coronavirus.
You might have just thought it was a cold novel, Corona Vic Viruses Youve, probably heard that in the news lately yeah. This is different, because this is an animal coronavirus that evolves and then infects a human and thus rendering it novel or new to US yeah, like those other coronaviruses, the ones that give us colds or whatever. Who knows how long they've been around and it's possible. They followed the exact same process that these novel coronavirusesn't followed, but this novel coronavirus that causes covid. Nineteen, like you, said it's new to us, and we think that it literally just made the jump from animal to human, possibly in a live animal food market in Wohan China, as recently as late December, two thousand and nineteen yeah, so there's kind of a lot to this.
I think they pretty much are positive that that's what happened.
They think that they have a patient zero.
Fifty five year old man from the Hubai Provence M, but they're not positive about that, and now there's some debate about the timeline.
Officially, it was December thirty Firse, but now they're saying it may have been first detected in Midnovember.
The patient, zero is not confirmed.
Theythey've also think they have zerodon the fact that it just like in the movie, contagion and started with a bat and then this animal. This very strange animal that ad never heard of before called a Pangalin has served as the intermediate host because they did genom sequencing of the virus and it has a ninety nine percent, identical gnum sequence to that of when it's in a human yeah that it's really interesting. To think that, if you look at a lot of the research chuck that we're hearing about and we're learning and just generally stuff that people walking around know about coronavirus, it has come from China doing an astounding amount of research and work on examining and trying to figure out and trying to defeat this coronavirus. So I mean they've they've. Definitely done a lot of work.
You could say for to kind of explain to the world what's going on, even though I believe there they're pretty roundly criticized for potentially not warning the world in enough time, but I guess that's Giting, that political stuff, yeah and just to be clear: finding a patient zero isn't so they can.
You know, say you did it, you did it you, you have to pay for this yeah.
It's helpful in trying to figure this whole thing out. That's why timelines are important tracing it back to as roots as important right since that time, China is close down about twenty thousand wildlife arms to try and curb and part to try and curb the PENGAL and trade yeah, which is a delicacy to eat in China.
But I just read today, apparently in Nigeria they acount for about fifty five percent of the Pengal and trade and the penalty they already had in place is still the current penalty, which is two s and seventy cents for a first time offender. So there's a lot of pressure on Nigeria right now to shut down their trade as well wow and yeah penkaling is it's a mammal right, but it is covered in like these kind of dragon like scales, and it looks like a small aunt eater.
It looks like a dragon head sex with an aneator yeah and it's tough to look at like it hurts my teeth. Looking at pangolins for some yeah, I can't quite put my finger on why, but it's almost like they just shouldn't, be or something well, I'm not going to say what I was going to say all right cool.
So let's talk about the spread of Covid, okay, so theyre the way that it's spread initially or the way that just about well any zonotic virus. I'm not sure if all viruses start like this, but they usually typically start in an animal, and it spreads through close contact between an animal, a sick, animal and human who then contracts that it's a zenotic transmission right from animal to human, great band name. It is I'm surprised we haven't hit on it before yeah and then so. That's a animal to person transmission from that point on that person's infected, they get sick and then they transfer it to somebody who who comes in close contact with them, which will talk more about, but these days close contact for coronavirus and covid. Nineteen is considered within six feet for an extended period of time or present with somebody sneezes or coughs in you know a small area and then that person can get sick, that's person, O person, transmission and then the last one, and this is the one that's the hardest to deal with, and the one that we're seeing right now. The stage that we've entered around the world is whats called community spread yeah that one's the scary one, because that's the final stage where people get sick who, as far as they know, didn't, have any contact with another sick person. Right - and this is when you know those very first stages of the outbreak, it was all person to person, after obviously the animal transmission and then, when it developed into community, spread.
That's when people started to get a little freaked out. I think yeah, because I mean they can't say. Oh, I was around.
You know, Timmy who's, sick with this right now, so I got it from him. It's like. I have no idea where I got this yeah. That makes the whole thing scary.
It makes people freaked out. It makes it much more difficult to to contain when people don't know where they're getting it from and it it makes. You need to take much more deconian measure suit to prevent the spread of this stuff. It's where it starts to get out of control is when it hits community spread.
Yeah - and you know when you see like these graphic maps of how it's spread, it's really frightening is the only word that can be used to describe how quickly this thing his taken hold - and you know this is stuff that everyone knows unless you've just been under a rock or like my friend clay about a week before this happened. He went to Nepal for a to M biking trip really yeah wow yeah.
I was like well, that's your new home buddy. I hope you like it is he there still yeah he's still there? Oh my gosh.
Is he o Vey Time? Okay, that's good he's, not sick or anything he's just hanging out yeah. I don't think he's seen a lot of people. Oh I'll bet, I think, he's deep. You know into the woods and stuff.
Well, man, that's about as good a place as you could possibly be right now, yeah and he was planning on being there for two months anyway.
Yes, he had a plan, a trip. It may not have been two months, but I'm not sure I mean I am concerned about it. Obviously, but he says everything's cool yeah: it sounds like your friend clay may be one of the luckiest people in the world.
Maybe wow well, keep it keep addic clay, you're, doing social, distancing right just go to Nepall and stay in the woods.
Should we should we take a little break here? Yes, we should all right, let's Break Im and we'll talk about some of the symptoms right after this ye should know AAND shostuff. You should know okay chuck, so we're talking about symptoms here there it turns out so the the there's like a classic set of symptoms that they now recognize, as if you have these there's a really good chance. Right now that you, you have covid. Nineteen, the the cluster o symptoms are a fever. It's usually a high fever.
A dry cough is a really dead, giveaway and a dry coffise. You know where, where you it's almost like, the back of your throat is tickling and you can get no relief from it and you're not like coughing up phlem. That can help get rid of that cough to that sensation of needing to cough. That's like a dry cough yeah, which is really troubling right now, because it's pollen season, righter in the United States and drycough for a lot of people is a regular thing every spring. So it's especially worrisome, I think, for a lot of folks with allergies yeah for sure and and I keep getting like - I don't normally get allergies, but it's pretty bad this year and I'm like I've got not a dry cough, but you know little tickle here there.
My nose is a May, be a little runnyn here there, so I'm like always really paying extra attention to that stuff. It's it's exhausting, basically yeah and then the third one is so you've got fever, dry, cough and then difficulty breathing shortness of breath. That kind of thing and from studies they found according to the Journal of what is Jama Stan for, I used to know o the Journal of the American Medical Associationda Yeah, so Jama found that on average people start to display that symptom of shortness of breath within five days of the onset of the rest of their symptoms.
So if you have a fever, if you have a dry cougf an after a few days, you start to develop a shortness of breath or difficulty, breathing you're, a really good candidate to get tested for covid and and maybe need to go t the hospital yeah and I've seen I've seen the chess thing described from people who have coronavirus or covid. Nineteen is everything from you know: a fifty pound weight on your chest to good l to a belt strapped around their chest that just keeps getting tighter and tighter that you cant unloosen. That sounds awful yeah. It sounds very specific if you feel actual severe pain and pressure in your chest.
If you have bluish lips or bluish face yeah, that's fair.
If all of a sudden you're confused and you normally aren't confused mentally, then those are signs that they say you really need to get to the hospital right away.
Yeah for sure I mean that's anytime, your skin or lips ar blue. That's that's a bad sign!
That's one of the big signs of Covid is that difficulty breathing leads to a lack of oxygen, which is why everybody keeps talking about this need for ventilators part of this process of a really bad case of covid. We're talking about a bad case here.
All right is that you may need a ventilator to help you breathe because you're not getting enough oxygen into your lungs breathing on your own.
So that's why ventilators have been kind of like celebrity stars really sought after in this in this pandemic, right now, yeah, and why the shortage of ventilators is super scary, because when you've got in that situation and we'll talk more about the biggest fear, which is overwhelming the medical system right, but then you have potentially mile cases that develop in o, more serious and even fatal cases.
Right yes, and that typically seems to be in seen most in people who are older. I think sixty five and over is that in graduated, increased risk from that age forward, people who have compromised immune systems already. I think people with diabetes are all right risk, but for the most part, something like eighty percent of cases of covid are relatively mild and are going to appear to you to be just like a seasonal, cold, runni nose cough sore throat, just just something that you would wouldn't even need to like do anything more than take some medicine at home. For the vast majority of cases of people who are who have are going to get covid, nineteen are going to experience a mild case.
It's actually yeah it's, I guess what I'm trying to say is don't be freaked out. It's very rare to get these extreme cases compares right.
Yes, statistics are on your side, yeah and that's how it's treated as well. In mild cases, it's treated sort of like the flu. You get rest, you have a lot of fluids.
You try to manage your fever and, generally in side of a couple of weeks, you will recover in mild cases right.
One of the problems that I saw, though chuck is that when the case becomes more advanced and you have difficulty breathing it's it just kind of like reeks havoc on your lungs and the Air Sax in your Lungsavo Li start to become damaged and when they become damaged, they can very easily get infected and filled with fluid. And then you have pneumonia and that's an entirely different co morbidity that is difficult to manage, that that can kill you, but also isn't necessarily going to kill you. But it's another problem that they're finding can arise out of a covid nineteen infection.
Yeah, I think date has her down. The latest statistic is about one to three percent of infections get to the secondary pneumonia, and if that happens, you have what's called ards acute respiratory distress syndrome and the scary part about ards is thirty to forty percent of those cases end up proving fatal right yeah or give even if you have a ventalator right and one of the things that's kind of confounded people studying this pandemic has been like that every once in a while, a young, healthy person will die from this and it's very puzzling. It doesn't make a lot of sense, and I saw that there was a an article in the landset from January twenty. Fourth, that talked about a study that found that in cases where people were severely ill, they found whats called the CIDOKEENE storm, which I know we've talked about before. But basically your body throws everything. It has atthis infection and it's actually an overblown immune reaction, so so much so that it, your body, attacks its own organs and you can die from multiple organ failure.
Again. This is in the worst case scenarios, but it doesn't explain why some younger, healthy people have mysteriously died from this.
They think that it's their body just overreacted to the to the illness yeah, and you know I know that they have to report accurate findings, but I think one of the things that is certainly not helped with the social distancing is the initial news that it's really only a problem if you're elderly or over a certain age right, and so now that I mean since then the messaging has been really wramped up on millennials and younger people there'r stories every day. Now, where younger people are like, Hey I've got it. This is no joke. Please please, please, don't take this lightly. Yeah I've seen some people doing making videos like that and and good for them for doing that.
Yeah. We got a lot of things wrong early on in this in this outbreak in the United States. For sure, yes, you could say you could say that one of the other things I want to point out, though speaking about numbers and statistics, and everything, though, is that like when we, when we talk about like the rates of mortality which will talk about in a second, it's really important, to remember that you know, even if the mortality rate is as high as three percent.
That means that ninety seven percent of people who get it recover and one thing I've really been heartened to see chuck as if just in the last couple days, the the news agencies have started to report total cases and then next to that are recoveries.
And then, after that, our deaths, a used tos be total number of cases in deaths.
Now, there's a big old bar in between those two that's recovered people who have gotten the had come down with covid nineteen and have now recovered and are no longer ill.
Yeah I mean the fatality rate is I've seen four percent Dave has here?
Some people place it below one percent Soi'm above two, it's somewhere in that range and if you want to compare it to SARS, SARS had a fatality rate of about ten percent, but it was much more contained. So that's sort of the main difference in what we're seeing here with covid nineteen yeah, the the reason why no one can say at this point what the fatality rate actually is in part is because the testing was so flubbed early on in the United States that so few people were given tests.
The results were skewed right. So if you took a test for covid nineteen, the chances are. You had such terrible symptoms that you went to the hospital and they tested you there.
Well, that totally leaves out people who had covid nineteen, but had those mild cases and didn't go the hospital, and so they didn't get a test. So this vast number of people who came down with covid nineteen - and it was just like the flu or the common cold, so th their numbers weren't added to this, which makes the number of people who were tested and then died really disproportionate. t the actual numbers of people who die when they have covid nineteen, at least in the United States and in South Korea, which is held up as like this model for how to handle t a pandemic from this point forward.
They had plentiful, widespread testing early on and threw out, and they took a lot of really good containment measures, but because they had really good testing.
It became clear that the fatality rate, at least in South Korea, it was point seven percent, which is still higher than a seasonal flu, which I usually about point one percent, but it's not nearly as high as, like. You said, four percent, so our understanding of the actual fatality rate is not it's not clear yet, but it's probably a not anywhere near as high as four percent yeah, that's what the thinking is and the you know the asymptomatic individuals they are asemps is what I call Hem.
That's another one of the the scary parts about it. Is it's hard to get accurate numbers on even the number of people that have it because there could be there could be people, there could be far more people that have it that just don't develop the symptoms and are still spreading it because they think they're great right, they're, an enormous problem and that's one of the things I know we've talked about this before, but like a worst case scenario for a virus is one that infects a person but takes a while for symptoms to show up because, like you said, they're asimps walking around infecting everybody else because they can spread it even though they don't know they're sick yet and by the way chuck a Simps, excellent band name: It's not bad! Is it and I see them all with matching Monchi ch haircuts the whole the whole four five piece fan interesting: The a simps Monchi Chi was that sort of like I remember the song ironically, but I can't picture they're their little fuzzheads weren't. They they were.
They were kind of kind of like moptop, like the Beatles with their matching her becuse early on.
It was a little like that. I guess all right, you saying the Beatles were Acemps the yeah.
I think that was their original thei original name with Pete best in Hamburg wowall right. Let's talk about how to how it spreads you did mention earlier, but it bears repeating this six foot rule is because you are most likely get infected by being sneezed around being coughed around and getting those airborne droplets from an infected person, even though they do know now it can live on surfaces and there they're rapidly trying to test how long it lives on various types of surfaces, because that's that's a big big deal. Yeah so, and I didn't know this, an infected surface is called a phomite. Did you know that I don't think so so grocery store cart, handle fomin, potentially plastic from a a glove Uif. It's a plastic glove pomite! It's a Pho mite yeah cardboard.
I know that they're testing cardboard a lot right now, because a lot of people, obviously yo're getting home deliveries now right and just quick little nondoctor recommendation from Dr Chuck here.
When I get a package now I go outside with my surgical gloves on yeah, I opened it on the front porch and I put a fire bomb in that tar. Boardi box barris push it into the street yep very smart Oy, but I don't I don't bring that outer box inside, though at all. No, no, no, you send it down the street a flame in a wheelchair, like Philip, see more Hoffan a hopful dragon man. That was a one of the creepier images in movie. History, I think, is great, especially when he like hits the wall in like derts backwors that thatis great the the the there was A.
I think, a NIH study that looked at fomites.
It found that in the air, when somebody sneevs sneezes their coughs into the air that erosolized air or aerselized virus sorry can can survive for three hours in the air four hours on copper surfaces, twenty four hours on carboard, two to three days on plastic and stainless steel.
The thing is: This was really reassuring, because I too have been super worried about things like boxes or touching grocery carts, or anything like that.
The CDC says that, up to this point, there have been no documented cases of infection from phomites right.
That's huge man, that's huge, because that means that if, if you're not around a sick person, at least up into this point at least documented wise, if you haven't been around somebody who's sick, you haven't gotten it from touching something, and that's a big thing that people have been talking about is like don't touch your face is one way to avoid the spread which we'll talk about, but don't touch your face after not only like being around somebody, but don't touch your face after touching a carboard box or touching a grocery card, or something like that, because it could be a phomite, but the idea that no one has gotten sick yet from a FOMI. I found extraordinarily reassuring, although it's not like, we should go, get Cocki now and you can just do whatever, but I feel like I can relax a little bit even though I'm going to be just as vigilant, I can be a little more relaxed about it.
Yeah I mean you're not going to go start licking. Grocery cart handles, like you usually do man, some of the tastes I've discovered or I thoutmos Laik. That's it's like the impossible, colors version of tastes and some some like almost something that HP lovecraft would h, have trouble describing like UNNAVAABLETO.
Well, that's how you discovered the the new form of Umami that had previously been undiscovered right, right, Jumanji and to be clear to this whole cardboard box on the porch thing in the surgical gloves. For me, that's a an abundance of caution just being like.
You know why not just leave it on the porch yeah. Just because I don't know, and the serchcool gloves thing and keep in mind. I really literally haven't left the house in ten days. I don't think but previous to that I was wearing the gloves like when I had to run to the store to get our stuff.
Just so I didn't have to sanitize my steering wheel and my car door handle and everything like that yeah every single time. I did anything, it's just smart yeah, it's really hard to do to like if you're.
If you think about it, you you're like wait, but I need my hand to touch my credit card, because but then I kneew my glove handed punch in the numbers for my zip code and like it's like, you really have to be on point to keep up with it and even then you're, just it's impossible to be perfect. You know, yeah, I mean we've been again. We haven't been out much at all, but when we have had to be out were sanitizing our credit cards when we come back, we spray our door handle, and you know not like Howard huges level stuff, but just just trying to be smart right, although Howard Hugh's level stuff right now is not not the worst idea like. I have nonx boxes on my feet, right now, no, no, no judgment, of course, so chuck we were talking about how it spreads.
What actually happens with this virus is once somebody coughs or sneezes or licks their hand and wipes a elevator button or something with it.
It's that is an infected surface, although apparently people haven't gotten sick from it yet, but more often than not, apparently you're going to get sick. If you are around somebody who caughs or sneezes - and you get it from the aerisolized virus when that right, when that virus enters your body through your mouth, your nose or your eyes, it sets up shop usually around in your throat, which is where that dry cough starts and the the reason that those those spiked proteins that form the coronavirus's crown are there is because that's how it interacts with the cell and the way that it interacts with a cell is through an enzime. That's present on the outer membranes of most cells in the human bodies December enzim is called furin foreign.
I say: Furand Fu Rin, a miso fur andactivates that that protein spike and that's how the virus can pump its its genetic information into the cell, which hijacks the cells functions and says you're, making copies of me now and then it just kind of spreads from there.
And this is why they think that the that you can get things like diarrhea, like a cow or a pig or you can suffer multiple organ failure or can go after other stuff is because most of the organs and systems in your body have cells that contain Furin on their outer envelopes, and so the the coronavirus can can interact with just about any cell that has fuarin yeah and it make me really uncomfortable for you to talk about my outer envelopes in diarrhea and cows and pigs in the same sentence.
Yeah. It's all pretty bad. It is a little ban.
The and you know we talked about touching your face, which is tough for me as a nailbiter and just general oral orally fixated individual, that six foot, distance, disinfecting, light switches and door, knobs and countertops surely doesn't hurt, and - and I know everyone has heard this a gazilion times, but we would be negligent if we didn't talk about washing your hands with soap and water, hot water for at least twenty seconds, pretend your surgeon and you've seen shows about surgeons.
Just pretend like you're in the match camp, okay and just wash like they wash.
There was no chance that we were not going to reference match in this episode.
I know they there's different songs like the ABC song or I don't want no scrubs.
I guess you could sing like a surgeon if you want to do. Oh, that's a good one, but at least get in there for twenty seconds. We have handwashing parties at my house several times a day, even though we're not going out, we take our temperature every morning as a family, and you know because I took that trip to Philly New York and DC right. As this was launching to see Bonny Prince Billy - and you know, we went on two trains - two planes pin station in New York for God's sake, which is already the filthiest place on earth. Sure and I was not freaking out, but I was definitely at a higher risk than the rest of my family, so I've been watching stuff and tomorrow actually will be my fourteen day, yeah the end of my fourteen day window. So unless something really happens overnight, then I feel pretty good man. I'm glad to hear that. That's great that's got to be a big relief.
It is you know I try not to focus on it, but you know my wife and daughter didn't go to pen station right and didn't eat a Philly cheesestake at to in the morning right.
You know I know, and yet they could have suffered for it. You know yeah totally, so I think a lot of people are counting down days.
I know Yumi is from this past Thursday, which is the last time her dad went out to get supplies from the groser store and she's like nervously, counting back acounting to fourteen from from Thursday to trying to will you know him not to get sick, and I think that's just kind of like it's everybody's got these these little countdown clocks going on right now, Y of their own. It's just talk about like an anxious thing to do, while you're sitting around in your home, not not leaving.
You know waiting for days to pass right exactly you're you're, counting down the days in the hopes that in illness doesn't pop up in the meantime, like what its strange horrible thing for everybody to be doing right now, yeah, absolutely we should mention masks really quickly to the CD says: There's no need to wear a mask unless you are sick or you're caring from one for someone who's sick, if you're healthy, if you're, not sick, if you're keeping yourself clean mask aren't necessary, you shouldn't go out and buy hundreds of these things.
I mean I'm not going to judge anyone if they had some and they want to wear them out more power to you.
Some people say that they wear them to keep from touching their face because they're orally fixated, so that you know there's something to that.
But the rush on buying things like surgical maskses put a dint in the medical supply chain, which is not cool.
No, and, I have to say, like I know we're not getting political or whatever. But I've read a New York Times article with with this guy.
It was about masks in the mask shortage, and there was this one manufacturer in Texas who said man short of setting myself on fire in front of the White House. I've done everything I can to warn the government that we are in a really precar precarious position.
He said I told that the Bush administration, the Obama Administration and the trump administration that we rely on like ninety five percent of our medical masks from overseas and if candemic happens, we're going to be reliant on other countries who are dealing with their own stuff to send us masks - and he said that's even the case with American manufacturers who move their operations over seas for cheaper labor and, in fact, there's a company that makes medical masks and it's an American company that move their jam to France and France under this pandemic said well by the way we've taken over your factory, and none of these masks are leaving France, you can't send them anywhere, it's illegal. There are so Yeroso you're an American company. This is in France and we just nationalized everything. So man, this guy's been warning a everybody. I can't imagine what that's like to be to have seen this coming so clearly andto to just not be listened to. You know, because exactly what he predicted is panned out the boy all right. Well, let's take another break and we'll talk about containing the spread. Everyone's favorite. Two words. These days social distancing, yeah and a little bit more about covid nineteen right after this ta Yo should know and sho stuff you should know so I just want to say everybody.
I think it's laughable.
Anyone, including me who thought that I wasn't going to get political at all in this episode.
Well, you indicted the past three administration, so that's, okay. That seems fair and balanced, fair, an balance.
So until we have a vaccine, we can only contain covid nineteen.
It is about twice as contagious as the seasonal flu yeah. That's a big big big deal, yeah, it's very contagious and, like we said th, the the big fear right now, obviously is a loss of life, but the real real big fear is that the medical system becomes overwhelmed and treatable infections can become deadly because we don't have the resources that we need right. So the the in addition to social distancing. If that one isn't the Oxford English dictionary's word of the year, Oh yeah then flattening the curve, as got to be t's, one of those Hare Goo they're, going to tie for first probably, and we should probably explain what flightening the curve is for, like the three people who aren't already familiar with it, shall we yeah go ahead all right so fighting the curve? Is this idea that we're going to get x number of infections, because this is a pandemic? A lot of people are going to get infected by corona virus and become sick from it right.
But what we can manage is the time scale that that number of infections takes place over. So let's say we know that an area is going to get just, statistically speaking, a thousand infections from this pandemic.
It's way different to have those thousands and thatthousand infections, all at once over the course of one week, then it is to have that same number of infections, one thousand over the course of ten weeks. That's right because of the strain that it puts a medical staff and medical equipment. We have a limited amount of medical staff and medical equipment and, if they're all called for at the same time, that's a problem, but we can reuse that medical staff. We can reuse that medical equipment over the span of time, so a ventilator can support two patients who need it for a week each over the course of two weeks.
But it can only support one patient of those two if they need it on the same week. So flattening the curve is all about making th this. This number of infections that were surely going to see spread out over time, rather than happening all at once in the main mechanism for flattening the curve is social distancing, which is just stay away from one another to cut down on that rate of infection yeah, and you know what we try to remain judgment free on the show and tell people to live their life. But this is one instance where, if you ware not social distancing, if you were going out to bars and restaurants and having gatherings then you're doing a very, very bad thing right now, you're doing something extraordinarily selfish will stop, and I know a lot of people are like. Well, I'm young and it doesn't. Doesn't it's not going to get me and even if it does get me, I'm young and healthy I'll be fine. It 'll be like a cold.
The problem is, is you're the same person who's going out in public and then touching an elevator button and making that person sick or, if you are sick and you're out running around you're coughing you're, sneezing you're being gross in your airslizing, the air with the virus, which can stay VI viable for three hours. So your getting other people, sick and those other people might not survive that Covid nineteen case that you've given them because they're not young and they're not healthy, and the idea that that you' just flouting that that yeah is just it's, I think maybe blood boiling is the right term yeah it's. It really really has been pretty upsetting to see, even in my own super cool neighborhood, where people seem to do the right thing most times and on the the neighborhood pages on facebook. People are talking and doing the right thing, but you know even up until like a few days ago, I was driving through my little neighborhood area, where the bars an restaurants are, and some of them are still full of people, and I just like I want to like put a loud speaker on top of my car, like in Andoh Jeez. Why am I in slacker, in the link ladder film and just drive around saying, very bad things to people in public when I think a loudspeakers ind cars? I think of Blues Brothers Yeah that too sure - and that was that was probably slacker - was probably stolen from that anyway? Gotha did they use a cop car and slacker?
No, it's at the very beginning of slacker. There's this guy. Actually, he pribat in steal, ecause. I think it was a real dude in Austin that would just drive around sort of preaching to the masses from inside of his car.
But we need that guy right now to to get people in their houses. Man, like it's a couple weeks, just do it just do it it's easy, especially for two guys who can continue to work from home to say that so absolutely sure and don't I don't want to give the impression that we don't have any sympathy and our hearts don't go out to people who who do work at those bars and restaurants and need that money to survive and so staying at home, and if everybody else stays at home like really deeply affects their potential to hang in there and survive like like that's not lost on us, that's not lost on anybody. I don't think yeah and, I think t the thing that t is the most blood boiling ore people who who are going out and like not doing anything that that has any economic impact, ther's just being jerks, there's like playing basketball or they're just going to the beach.
You know like like that kind of stuff is what drives me the most crazy yeah, just knock it off it had. The heartening thing to see has been how many people are stepping up to contribute to their local favorite restaurants and bars, whether it's a Gofun me or supporting their curbside, pickups or or just venmoing your favorite server, some money, that's happening all over the place to try and keep people solvent while this is going on, but the big picture is: If we don't do this now, it's just going to be more drawn out and people are going to be more affected economically.
So the right thing to do is just to shut it down for a little while yeah that I mean from everything I've seen what we're doing now.
This kind of half hearted approach to social, distancing and quarantining like or getting all of the negative economic effects, but rutle to none of the public health benefits so we're doing it in the exact possible worst way. Right now, yeah, I saw one doctor say that if you could literally just hit a pause button yeah in the United States right now, there would be no covid nineteen in two weeks yeah. If we could freeze everybody just free six feet apart for fourteen days, Tha the virus would stop in its tracks and we've seen. This is the thing this isn't like conjecture, this isn't philosophy or modeling, or anything like that.
This is based on what we've seen in other countries like Singapore, Hong Kong, China. Even Japan has done a really good job of quarantining where they have they've basically figured out the way to contain. This is extensive and widespread testing for the disease and then really strict and really well followed a meticulous social dancing and quarantinine people taking it seriously so that you can test the people to see who have it and and isolate them, quarantine them treat them to keep them away from everybody else and test other people as as time goes on, so that you can have people living a normal life because they're not sick and the people who are sick have been identified and are being quarantiede and isolated while they're being treated yeah. I mean it's, it's very easy to look at a place like Singapore and look at a country like Italy who did not do it right, ind America, Italy was just before us.
These are two great examples of the difference that this can make.
As of today, Singapore has five hundred and fifty eight cases, and, despite that, I just saw a new announcement today that they are closing schools and closing entertainment venues just because they're really trying to be super proactive and get out in front of it. Yeah Italy, the INFICTION, the infection rate, was almost nothing throughout February yeah. This is I'm boggling and then, in March it spiked to twenty five housand new cases a week, two weeks later, yeah twenty five thousand. This is these are numbers that should speak for themselves and you shouldn't have to talk people into social distancing. Yet here we are, you know it's saddening, the the the one other problem, or I guess the big problem again - is the idea that if a lot of people become sick, if you have a spiking cases like Italy saw where it suddenly goes up to twenty fivehosand new cases a week.
A lot of those people have to be hospitalized and it stretches and overtaxes and eventually overwhelms the health care structure in the in the country and in the United States, like every town, has a brand new gleaming hospital and lots of doctors, but it turns out. If you look at the statistics, the United States has a paltry number of hospital beds per onethousand people.
We have two point: Eight hospital bids per one thousand people which even sound small, but if you put it in context, it's really small, Japan and Korea have the most they've thirteen point, one and twelve point three hospital bids per thousand people. Next is Russia at eight point one in Germany, eight point, Oh and then you go there's a lot of countries in between Germany and the United States, which finally POPs up with two point. Eight hospital bids per one thousand people - The problem is: That's just hospital beds. That's just a bed to put people ind, that's not specialized hospital beds like people with a bad case of covid. Nineteen frequently need like an I see you bet, and so ih already in the United States in hardhid areas like New York, we're starting to see.
I see you rooms that were meant to hold one patient starting to be tripled and quadruplled up with patients who all have covid nineteen just to just to try to give them t e the advanced level of care that they need, because we don't have enough beds, and so that's why that that not social distancing.
Why just going out and carrying on like nothing's going on, is just such a ridiculously arrogant thing to do at a time like this yeah, and I feel like every day, it's gotten a little bit better like you really have to be pretty selfish, and what's the word there's a word that I can't say on the air, for when you've got a lot of gumption to do something. Despite everyone saying you shouldn't guts, not guts, because that idmar bravery nerve you guy ar there you go yeah like as of today when we're recording this, which is two days before release.
If you're still out doing things like that now, then you really have got a special brand of nerve yeah and unconversely too.
We should point out to Selfquarantine is a gift: That's a gift you're, giving other people nobodyis telling me! There's no martial law, you're not going to be shot on sight or arrested or whatever. If you leave your house if you've been exposed to covid nineteen, but the official guidelines from the CDC in the World Health Organization, as if you know you've been around somebody who is tested positive for Covid nineteen, they ask you to self quarantine for fourteen days, because fourteen days is the longest as far as we know that it takes for symptoms, to show up that's why people are counting down fourteen days right.
So if you hang out by yourself isolated away from everybody else, like you were doing for fourteen days and you don't get sick, you don't have covid and you're not spreading it. You're, not you're, not a risk factor any longer so, but to stop your life and to say I'm not going outside, because I don't want to risk other people getting sick because I'm not sure if I have it or not.
That is an enormous gift to give the people - and I mean it's what you did my friends, Mick Mitchin, Patrick. You Know Dirty Mitch from the skabies episode he he and his husband Patrick, were exposed to somebody with covid nineteen. They have no idea if they had ir or not, but the first thing they did was selfquarantine and they just committed to giving up fourteen days of their life of going outside of interacting with other people of doing whatever, just because they didn't know in part, because testing is not widely available in the United States. So this is the alternative. It's on it's on us to make that decision in that choice, and it is a really kind thing to do so. Howsoe YouTube Chuck for doing that.
Well, hats off to everyone, doing the right thing and you're right. Unless you're, rich and famous, it can be hard to get ats test right now, which is another problem, but we're not going to go down that rabbit hole either right.
Well, we've been at it for close to an hour, maybe let's wrap up with some talk of vaccine. Okay.
Obviously a vaccine is the ultimate end goal for all this.
There are a lot of organizations working all over the world rapidly trying to develop antest vaccines, the National Institute of Health, Walter, read, Army Institute of Research and countless others are trying they.
Apparently, the government is trying to cut a lot of red tape to speed things up, but it still has to go through clinical trials.
You can't just rush rush, something to market as much as everyone would like that yeah and it could take a long time could take up to a year to get results of these trials. I saw that the NIH vaccine trials could could be in full swing by the fall and that one has promised that Ma Mrna dsh tweve, seven three, because it was being developed for Mers, so they kind of had ahead start rumor Mers as a type of novel coronavirus. So they're like this might work for this.
This SARS cove to coronaviruswll find out so hopefully by the fall that one might be just banging. Who knows that's what we need as a Bangin, robust vaccine right, lots of chains, gold chains, a nice swagger to it just banging yeah, and I - and I don't think this is - is getting too political, although it is a little bit, but I just did a little last minute research and found out. You know: There's this drug called.
What's the name of it, Clark, no rim, desevire UHHUH.
So this is not FDA proof for covid nineteen. It's still got to go through the clinical trials, but it has been used as an emergency emergency measure to treat a couple of cases seemingly effectively and theyare, expecting some results from a trial in April, and I just learned yesterday, I just kind of dug into this this drug yesterday, the FDA granted the company, who makes it Gilliad sciences orphan drug status, and this is from one thousand nine hundred and eighty three orphan drug act, which is meant for rare diseases. Only coronavirus or cubid. Nineteen is obviously not it's speeding up to not be a rare disease, but there's a little loophole in that Orphan Drug Act. If you get exclusivity, which is what happened, they granted them exclusivity for to profit exclusively for seven years on this drug right. If, if you get at that end and that designation then before it hits that two hundred thousand person threshold, which means it's not a rare disease anymore than it sticks, and so yesterday the FDA granted Gilly had sciences exclusivity for seven years, which obviously the fear there is. That could lead to a block on supplies for generic versions to be super expensive yeah, and at the end of this article, that I read, I found out that a man named Joe Grogan who serves on the White House Task Force for coronavirus, lobbied for Gillyad sciences from two thousand and Leven to two two thousand seventeen, which is always a little bit concerning, and then these are the guys who have come up with an Antivibal drug that has shown promised to treat Coritin.
That's right and they have now, as of yesterday, been granted that seven year window to profit exclusively and block potentially blocked generic suppliers for making this and here's the real kicker. Here's the Cherry on th, the rotten cherry on top hat is that they were developing this for Ebola.
So it was developed with seventy nine million dollars of textpayer money, Oh boy, and now they have been granded exclusive status for seven years.
That's almost as much of a bedtime story is hearing about senators who were briefed about the pandemic and then went and sold all of their Sol a Bunc of stock before the stock market crashed without telling anybody about it well, also down playing the pandemic to Yeh, send thim to jail, send them to jail. There was a time in this country.
It wasn't very long ago were people who did that were stripped of any honor were basically drummed out of out of town on a rail by hi rate citizens.
There was a time ass country, so man that was Grandpa Clark all the way. Hat's right, I suddenly just grew patches on my elbows it, the God cardigans about to sprout out of before you wrap up. I would like just to know your biggest fear and all this, what has been your biggest fear loved ones dying. That's my that's! My biggest fear, I think you know economics is a huge one.
I'm really scared about that in the long, lasting effects, people losing their jobs and just the setbacks that comes from that, but ultimately people, people, people, I love and care about dying sure, especially unnecessarily. You know like the idea that that we could have done some things differently and there would have been abundant medical care. That's that's my greatest fear.
What about yours?
Well, I've seen in too many movies about like domino effect, type things.
So my I mean obviously worried about friends and love ones, but my biggest fear has been worst case scenarios, which is everything from the US military getting a large outbreak, and somebody like I don't know another hostile country, saying now's a great chance. Oh Jeez Chuck, I didn't even thought about that, or medical personnel or police forces things getting disrupted so much with our health professionals, R ar people who keep us safe, Uhhuh that things a e become really scary on a citizen level. So, like people are what scare me yeah and it becoming like the purge, or something like that right.
That's what scares me! That's great! That's great! That was a good one to end on chuck, because I mean the whole reason we ar e episode is to reassure people and then just pull the rug right out from under im at the last minute.
But you know what I having said that I'm always consistently reminded of the ability and the will of not only Americans but human beings to do the right thing and the vast vast majority of people will come together and not not gointo attack mode yeah.
I totally. I believe that I think that that people are generally good overall, a grear are definitely bad people out there, but I think the good ones outnumber hem and when pushed against the wall, the good ones can fight back pretty effectively ohagree. Also, I mean that kind of raises another point too that I found it's really easy to just kind of let your mind run away and focus on all of the terrible stuff that can happen or all of the terrible stuff that is happening, and you kind of have to you have to exercise your mind to not do that. You have to stay on top of it and remind yourself that you can also just as easily think positively too, and you got to try to do that in times like these for sure, and it times like these, I make it sound like this happens every couple years or something like this is definitely monumental and historic and in once in a lifetime, hopefully yeah one other thing. If you think that you might have covid nineteen, I found there's a self treeage tool.
They say that if you think you have a you should call your doctor, your hospital, nine hunre one and and say I think I have covid nineteen there's an online tool now: Gehr Cov ID Tri age, dot, Akido Lab scom, Gar, Covid, trioj D, Aqito Levscom, and it's just basically a questionnaire that says hey. This isn't a diagnosis, but this might this might give you clear a clear view into whether you're just sitting there freaking yourself out or else if this this is actually something you might need to call your doctor or your hospital about alright good stuff, and hopefully all of this will be a weird distant memory, not too far from now, and since I said that, its time for a listener - mail, yeah, you know what I think, instead of Listen Mail on this one, let's just encourage people to be kind of one another, be cautious, be smart, help out someone in need. If you can and just hang in there. I know we have listeners right now that that have covid nineteen statistically, that's that's just got to be the case, so be well, and please take care of one another Yep and think positive. Everybody think positive right. If you want to get in touch with this, while you're hanging out socially distancing being responsible, you can send us an email can wrap it up. Spank it on the bottom, maybe wipe it off with some licesall wipes or something first and send it to stuff podcast. I heart RADIOCOM Stuff You Should Know, is a production of ihart radios. HOUSESTUFF works for more podcast for my heart, radio, ECAUSEIT, the IHAT, radio, AP, apple, podcast or whereever. You listen to your favorite shows