49ers Talk: A San Francisco 49ers Podcast

The 49ers bounced back in a big way with a statement win over the New York Giants. San Francisco was laser focused in all three phases, never looking back after taking a second-quarter lead. The 49ers' offense was humming all afternoon, scoring a season-high 34 points while Christian McCaffrey added a pair of touchdowns along with 173 total yards. San Francisco's win didn't come without cost, as 2025 first-round draft pick Mykel Wi...

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 9 matchup vs. the New York Giants and how he scripts his first 24 offensive plays. Also, Greg Papa joins Matt to assess the 49ers’ season at the halfway point and discuss key matchups for Sunday’s game.

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(7:46) Kyle Shanahan discusses difficulties traveling for early East Coast games
(8:55) Shanahan shares his process scripting first 24 offensive plays
(14:3...

In need of reinforcements along their injured defensive line, the 49ers made a trade with the New England Patriots for defensive end Keion White and a 2026 seventh-round draft pick in exchange or a 2026 sixth-rounder. Matt Maiocco and Jennifer Lee Chan discuss how White bolsters a 49ers defensive line whose nine sacks are tied for the second-fewest among all NFL teams this season. Matt also sits down with NBC Sports Boston's Patrio...

The 49ers came into Week 8 knowing the Texans' defense was elite, but it was Houston's struggling offense that took over Sunday at NRG Stadium. Heavily scrutinized QB C.J. Stroud executed a sound game plan for the Texans, while 49ers teammates George Kittle and Jake Tonges each caught a touchdown on on national Tight Ends Day to keep San Francisco's comeback hopes alive. San Francisco's offense lacked much rhythm beyond that, and t...

Matt Maiocco sits down with 49ers coach Kyle Shanahan to discuss the team's upcoming Week 8 matchup vs. DeMeco Ryans' Houston Texans. Also, Greg Bethune, father of San Francisco linebacker Tatum Bethune, joins the show to discuss his son's journey to the NFL

1:00 - Intro

10:00 - Kyle Shanahan Interview

31:00 - Greg Bethune Interview

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Eddy Piñeiro leads the NFL in made field goals without a miss through Week 7, but the 49ers kicker's journey to San Francisco has been anything but perfect. Jennifer Lee Chan sits down with Piñeiro, who shares why he chose to play for the 49ers after Jake Moody's release and how close he came to signing elsewhere. Piñeiro discusses how he brings a jolt to the 49ers' locker room, his fast-growing bond with George Kittle and why foot...

Without their fearless leader, Fred Warner, the 49ers' defense produced a masterclass performance against the red-hot Atlanta Falcons on Sunday while the offense ran all over the field. Matt Maiocco and Jennifer Lee Chan discuss how San Francisco produced one of its most complete performances this season as players stepped up and embraced the challenge of facing a top opponent. With the return of George Kittle and many backups step...

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 7 matchup against the Atlanta Falcons, and how losing Fred Warner for the season will impact their young defensive players. Also, Jennifer Lee Chan joins the show for an exclusive interview with NBC Sports NFL broadcaster Cris Collinsworth and analyst Devin McCourty to discuss the loss of Warner, Nick Bosa and more.
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(4:32) Shanahan discusses impact of lo...

After a long NFL journey, wide receiver Kendrick Bourne is back with the team who first took a chance on him, and he's beyond grateful for his second 49ers stint. Bourne sits down with '49ers Talk' co-host Matt Maiocco to discuss his path back to San Francisco and how the time away made his return that much sweeter. Bourne details his development over his nine NFL seasons and why he's so happy to be back in the Bay Area. Also, Bour...

 The 49ers' health woes continued after San Francisco lost superstar linebacker Fred Warner to a season-ending ankle injury in Sunday's loss to the Tampa Bay Buccaneers. San Francisco responded valiantly, managing to stay competitive throughout the matchup before fading late in the fourth quarter. Baker Mayfield and the Bucs' high-powered offense proved to be too much in the end as the 49ers suffered their second loss of the season...

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 6 matchup vs. the Tampa Bay Buccaneers and how rookie defensive lineman Alfred Collins has made significant strides this season. Also Greg Papa joins Matt to discuss what QB3 Adrian Martinez will bring to 49ers' offense if Mac Jones gets injured on Sunday.

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(10:18) Kyle Shanahan discusses 49ers taking advantage of long week to recharge
(15:41) Shanahan sha...

Star 49ers running back Christian McCaffrey is off to a hot start offensively this season, showing shades of his 2023 AP Offensive Player of the Year campaign. McCaffrey sits down with Matt Maiocco to discuss a plethora of topics, such as learning route-running from his Super Bowl-winning father, identifying the most valuable asset in professional football and describing how George Kittle helps bring "fun" back into the game. Also,...

Matt Maiocco shares the 49ers’ injury update before sitting down with Greg Papa to recap San Francisco’s thrilling 26-23 overtime win over the Los Angeles Rams on Thursday night at SoFi Stadium and discuss how the victory can set the tone for the rest of the season.
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(2:25) Matt shares 49ers’ postgame injury updates
(5:03) George Kittle not likely to be available Week 6
(6:10) Matt recaps 49ers’ thrilling 26-23 overtime win
(11:30) Ma...

An injured 49ers squad defied the odds and dug deep for a 26-23 overtime win over the Los Angeles Rams on Thursday at SoFi Stadium. Backup quarterback Mac Jones delivered his third win in three starts despite laboring through pain all game. Kyle Shanahan managed a very limited and at times inexperienced San Francisco squad, and rookies produced when their numbers were called. Matt Maiocco and Jennifer Lee Chan discuss how the 49ers...

John Lynch joins Matt Maiocco to break down the 49ers' first four games of the 2025 NFL season, from how San Francisco's rash of injuries affect his front-office priorities to some of the more positive on-field developments during their resilient start. Jennifer Lee Chan also joins Matt to preview the 49ers' Week 5 matchup vs. the NFC West rival Los Angeles Rams this Thursday at SoFi Stadium, and points out an area of vulnerability...

An afternoon of errors resulted in the 49ers' first loss of the 2025 NFL season Sunday against the Jacksonville Jaguars. Despite a second-half comeback attempt, San Francisco couldn't overcome its four turnovers. Brock Purdy's looked shaky in his return from injury after missing the last two weeks with turf toe. Matt Maiocco and Jennifer Lee Chan discuss how a subpar performance from all three phases contributed to the 49ers' first...

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 4 matchup vs. the Jacksonville Jaguars and also discusses Nick Bosa’s season-ending ACL injury. Greg Papa joins Matt to discuss defensive coordinator Robert Saleh’s comments about the Jaguars’ signal stealing and Brock Purdy returning from injury.

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(7:17) Kyle Shanahan discusses 49ers’ gritty wins to start 2025 NFL season
(10:46) Shanahan shares reaction t...

Despite their undefeated status, the Nick Bosa-less 49ers must persevere as the Jacksonville Jaguars visit Levi's Stadium this Sunday. Matt Maiocco and Jennifer Lee Chan discuss who will step up in Bosa's place and how San Francisco can adapt in other injury-bitten position groups. Plus, Matt and Jennifer detail how Demarcus Robinson will integrate back into the fold and how it affects the receiving corps. Finally, the nominees for...

The 49ers have endured a rash of injuries to star players to start their season, and that list grew emphatically by one more player Monday morning following the news that defensive end Nick Bosa reportedly will have to undergo season-ending surgery to repair a torn ACL. On this emergency episode of '49ers Talk,' Matt Maiocco is joined by Carlos Ramirez to discuss the fallout from this massive injury. How will the 49ers proceed, who...