Razib Khan's Unsupervised Learning

Razib Khan's Unsupervised Learning

Razib Khan engages a diverse array of thinkers on all topics under the sun. Genetics, history, and politics. See: http://razib.substack.com/

Episodes

July 28, 2026 80 mins

Today Razib talks to Jason Scharf, a biotech investor and podcaster. A native of San Diego, Scharf is an angel investor and startup advisor focused on the intersection of biology, technology, and business, particularly within TechBio and digital health. He has leadership experience in strategy and market intelligence at major companies like Illumina and Amgen. Scharf now targets investments in the bio-innovation...

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On this episode, Razib talks to streamer and political commentator Destiny (Steven Bonnell II). Destiny first gained prominence in the late 2000s as a professional player and content creator in the video game StarCraft II. Over time, he transitioned from gaming into politics, philosophy, culture, and current events, becoming one of the most influential figures in online debate culture. Known for his fast-paced argumentati...

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The UK is now in political turmoil, as Keir Starmer has announced his resignation. The next British election is still three years away, but it is hotly anticipated because Labour is going to faceoff against three parties of the Right: the Tories (also known as the Conservaties), Reform UK and Restore Britain. Reform, led by Nigel Farage and stocked with defections from the Tories, has a good chance to win in 2029. On today's e...

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Today on Unsupervised Learning Razib talks to Zineb Riboua, a research fellow and program manager of Hudson Institute's Center for Peace and Security in the Middle East. She specializes in Chinese and Russian involvement in the Middle East, the Sahel, and North Africa, great power competition in the region, and Israeli-Arab relations. Riboua's pieces and commentary have appeared in the Wall Street Journal, ...

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June 19, 2026 75 mins

On this episode of Unsupervised Learning Razib talks to Brianna Wu. Wu is an American video game developer, programmer, and political activist best known as the co-founder and CEO of the independent game studio Giant Spacekat. Raised in Hattiesburg, Mississippi, she attended the University of Mississippi to study journalism and political science but withdrew in 2001 without earning a degree in order to pursue early e...

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On this episode of Unsupervised Learning Razib has a wide-ranging conversation, again, with Dan Hess, the man behind the More Births account on social media. An engineer with a large family in the DC area, Hess' essays on topics like Israelis' high birth rate have gained the attention of X. He has an account that has come from a few hundred followers to more than 45,000 in less than 4 years. His tweets...

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On this episode of Unsupervised Learning Razib talks to geneticist Leonidas-Romanos Davranoglou about two papers, Ancient DNA evidence for the history of the Albanians and Uniparental analysis of Deep Maniot Greeks reveals genetic continuity from the pre-Medieval era. He is an entomologist and evolutionary biologist specializing in insect morphology, biomechanics, bioacoustics, systematics, and ta...

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It's been a minute since we've had Nikolai Yakovenko on the podcast. Yakovenko is a former professional poker player,and was a research scientist at Google, Twitter and Nvidia. With a decade in computer science, Yakovenko has been at the forefront of the large-language-model revolution that has driven to prominence companies like OpenAI, Anthropic, and DeepMind, and an ecosystem that has birthed hundre...

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May 23, 2026 59 mins

On this episode of Unsupervised Learning Razib talks to Christopher Rufo. Rufo is a senior fellow at the Manhattan Institute for Policy Research. A contributing editor at City Journal, author of the New York Times bestseller America's Cultural Revolution, and 2025 Bradley Prize recipient, he also serves as a New College of Florida board member and Distinguished Fellow at Hillsdale College. He is a...

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On this episode of Unsupervised Learning, Razib talks to physicist Gregory Cochran. Cochran is best known for his work in human evolution, often at the intersection of biology, anthropology, and history. Trained in physics, he later turned to population genetics and became widely known through collaborations with researchers like Henry Harpending, producing influential but controversial work on recent human evolution...

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On this episode of Unsupervised Learning Razib talks to Russ Greene, who promoted the idea of "Total Boomer Luxury Communism." Greene currently serves as the Executive Director of the Prime Mover Institute, a public interest organization and think tank he launched to advocate for American energy dominance. Previously, he was a Senior Fellow for the Economy at the Stand Together Trust. In this role, he managed a grantmaking por...

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The full episode is available here: https://www.razibkhan.com/p/10000-years-of-selection-in-western

Despite the preprint being out for two years, Akbari et al.'s Ancient DNA reveals pervasive directional selection across West Eurasia publication in Nature this week has resulted in a massive media response. Though Razib has discussed this work before, he thought it would be useful to review it, and put it in cont...

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Today Razib talks to Matthew Schmitz, a journalist who previously served as an editor at the religious journal First Things. He is the cofounder of the online magazine Compact, alongside Edwin Aponte and Sohrab Ahmari. He currently serves as editor of Compactreligion editor of Washington Post Opinions, and co-host of the podcast Against the GrainCompact His essays on p...

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On this episode of Unsupervised Learning Razib talks to returning guest Megan McArdle. She is the author of The Up Side of Down: Why Failing Well Is the Key to Success and a Washington Post columnist and op-ed board member. McArdle grew up in New York City and attended Riverdale Country School. She obtained an undergraduate degree in English from University of Pennsylvania and an MBA from the University of Chicago. McArdle's previo...

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You can find the complete monologue here: https://www.razibkhan.com/p/monologue-race-genetics-history-and

This is where you will find all the podcasts from Razib Khan's Substack and original video content.

On this episode, Razib talks about race, and how to think about this touchy subject.

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You can find the complete monologue here: https://www.razibkhan.com/p/monlogue-out-of-africa-is-not-dead

On this episode Razib talks about where we are when it comes to "Out-of-Africa," Neanderthal origins and the broader state of understanding the dynamics of Homo evolution.

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Today Razib talks to Chris Bradley, a serial entrepreneur and the CEO and Co-Founder of Matter Bio, a company dedicated to preserving genome integrity and addressing the root causes of aging. With a multidisciplinary background spanning neuroscience, cell biology, and computer science, Bradley aims to translate early-stage biotech concepts into practical therapies that can extend human lifespan Matter Bio is focused on di...

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Today, Razib talks to Chris Masterjohn, a nutritional scientist and leading expert in mitochondrial biology who believes hidden energy bottlenecks underlie much of modern disease. After years of work as a professor and researcher, he founded Mitome, the first mitochondrial analysis designed for everyday health, and serves as its Scientific Director. His mission is to make mitochondrial testing accessible so people can ide...

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On this episode of Unsupervised Learning, Razib talks to Mike White, a Genetics professor at the Washington University in St. Louis. White has a position at the School of Medicine in St. Louis, where he leads a research team focused on understanding the biophysical architecture of regulatory DNA. He earned a B.A. in music before pivoting to the sciences, receiving his Ph.D. in Biochemistry from the University of Rochester in 2...

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On this episode of Unsupervised Learning Razib talks to Aaron Renn. Renn is a writer, consultant, and urban analyst known for his work on the challenges facing American cities and religious institutions in the 21st century. He is a contributor to The American Reformer and the author of Life in the Negative World, a book exploring the cultural shifts regarding Christianity in America. Ren...

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