What Could Go Right?
It's easy to be pessimistic, especially with headlines dominated by global challenges like a changing geopolitical landscape, the rise in authoritarianism, and a seemingly unstable global economy. But what if, despite all that, humanity is actually making progress?Join Progress Network Founder Zachary Karabell every Wednesday as he chats with leading experts like Ian Bremmer and Anne Marie Slaughter to challenge the negativity and find out whether we should be so pessimistic about everything from sustainability and polarization to the future of work. Plus, start your week right with Progress Network Executive Director Emma Varvaloucas, who delivers a weekly dose of essential good news every Monday. If environmental success stories and medical breakthroughs are your thing, you won’t want to miss it.Tune in to discover the evidence for progress and find your reason for cautious optimism.
Episodes
Legal betting has exploded in the US. With the phone in your pocket, you can bet on the specific outcome of a game or who will attend the next State of the Union address. But legal betting has plenty of controversy, including how it affects sports fandom and the way it’s marketed to young men. Are the concerns overblown or do we need a real plan to address real harm? Two guests join our host Zachary Karabell for this conversa...
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September 21, 2026 • 17 mins
Maps have distorted the true size of the African continent for 500 years, but a new UN resolution is changing that. Progress Network Executive Director Emma Varvaloucas examines this historic shift toward a more accurate projection to correct centuries of cartographic bias. Plus: a biological breakthrough that could prevent premature births, and the wild story of how Neptune was discovered 175 years ago.For transcripts, to join the...
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September 16, 2026 • 57 mins
In the United States, we have constant debates about long-standing systemic issues like classism, racism, and economic inequality, and we speak about these issues as if they are complicated and impossible to address. But what if history tells us that we already have the solutions to some of our biggest and oldest problems? What if there is a bold path that looks to the past to redirect our economic future?
Georgetown Law Professo...
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September 14, 2026 • 16 mins
There’s been a lot of doom and gloom around artificial intelligence taking our jobs. Even founders of AI companies like Sam Altman have said that many jobs will go poof and disappear. But is the AI job apocalypse all hype, or are we just in the calm before the storm? We dive in. We also discuss adorable dogs gene-edited to be hypoallergenic, and two women in New Zealand who paved the way for women’s rights. For transcri...
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September 11, 2026 • 56 mins
Are we trapped in a cultural doom loop that forces us to fear the future instead of dreaming of a better one? In this episode, futurist Ari Wallach joins host Zachary Karabell to examine why modern society defaults to short-termism and how we can fundamentally redesign our approach to tomorrow. They dive deep into Wallach's "Longpath" framework, exploring how Western death anxiety, a deficit of transgenerational empathy, and a cult...
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September 7, 2026 • 18 mins
What if you never have to wear a pink ribbon again? For years, experts called the medical dream of a personalized cancer vaccine impossible. Now, a new therapy written by an algorithm is making it happen. We're also talking about how Australian cyborg cockroaches could come to the rescue at natural disasters, and we get into the alliance that brought a California farming empire to its knees and created a historic labor movement.
F...
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September 2, 2026 • 49 mins
Is interest in space dying, or are we on the brink of our greatest interstellar discoveries? In this episode of What Could Go Right, Zachary Karabell sits down with Dr. Dakotah Tyler, an astronomer and astrophysicist who pivoted from a promising college football career to unraveling the mysteries of the universe.They discuss the existential threats and promises of large language models, questioning whether tech leaders can manipula...
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August 31, 2026 • 24 mins
This week, we want to share a podcast from our friends at Issues in Science & Technology. It’s called The Ongoing Transformation and it looks at how science and society are continually transforming each other.
From countless ads to outright scams, spam is an annoying constant of online life. But does it have to be that way?
In this episode, Rebecca Coyne and Jason Lloyd examine the history of spam. And take a look at e...
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August 26, 2026 • 61 mins
David Pakman is the founder and host of The David Pakman Show, one of the most watched independent progressive podcasts and online political shows. He's built an audience of over 6.7 million subscribers across social media platforms through calm, fact-based analysis and critical thinking. David joins host Zachary Karabell to discuss his new book, Pay Attention, coming out on September 22. They dive into the missed messaging opportu...
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August 24, 2026 • 17 mins
The media is constantly telling us that danger is everywhere. Between true crime binges and political rants, we're led to believe that our streets are a war zone. However, recent statistics released by the FBI tell a completely different story. Plus, we'll get into why video game fans have the resume the FAA is looking for. Then in our this week in history segment, we’re taking a look at a bad deal that sparked a massive non-...
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August 19, 2026 • 49 mins
Being a human being is an anxious experience, and to calm the fear of uncertainty, we’re obsessed with predicting the future. Whether spiraling about changes to the economy, politics, or culture, we’re desperate to know what’s coming around the corner. In this episode, host Zachary Karabell is joined by Carissa Véliz, philosopher and author of "Prophecy: Prediction, Power, and the Fight for the Future, from Ancien...
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August 17, 2026 • 13 mins
Winston Churchill predicted this nation would collapse, but today India is experiencing a massive economic glow up as it rapidly lifts hundreds of millions out of extreme poverty. We also investigate why crucial historical signs are quietly vanishing from America's national parks, and how an eccentric doctor's argument with mother nature saved countless lives from malaria. Join Emma Varvaloucas on this episode of the What Could Go ...
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August 12, 2026 • 39 mins
The concept of the American Dream calls up images of enormous money and fame that most of us will never see. But what happens to someone who actually becomes mega famous? Is it truly something to strive for? Is the cost worth it? Ronda Rousey, the superstar MMA fighter turned graphic novelist, joins Zachary Karabell to explain her approach to creativity, life, and happiness that rejects our traditional metrics for success. The disc...
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August 5, 2026 • 56 mins
Words like "de-extinction" and "cloning" are often associated with dystopian science fiction stories, but reality tells a more hopeful tale.Ben Lamm, CEO and co-founder of Colossal Biosciences, joins host Zachary Karabell to argue that de-extinction, genetic engineering, and biotechnology can fix the harms humans have caused to our environment and prevent us from passing down genetic diseases. Ben discusses the role of government i...
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August 3, 2026 • 16 mins
After decades of facing severe overfishing and cultural stigma, global shark populations are finally rebounding thanks to strict new international trade bans and expanding marine sanctuaries. Emma Varvaloucas, Executive Director of The Progress Network, shares how much our views and treatment of sharks have shifted over the last century and why there’s reason for optimism.
Plus: a team of 23 students in the Netherlands succe...
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July 29, 2026 • 54 mins
There is a massive chasm between what official data tells us about the financial landscape and how average Americans actually experience their daily lives. Mark Zandi, chief economist at Moody's, joins Zachary Karabell to break down why this disconnect exists and how a skewing of income distribution means different classes are living in entirely separate realities. They explore whether modern technological leaps like artificial int...
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July 27, 2026 • 16 mins
While the severity of North American wildfires and their deadly smoke has undeniably increased, humanity is quietly winning an invisible technological arms race against our changing atmosphere. Emma Varvaloucas, Executive Director of The Progress Network, explores how eight decades of innovations—from the invention of the HEPA filter to electrostatic N95 masks—are enabling individuals to mitigate climate impacts and bec...
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July 22, 2026 • 41 mins
We live in an era of limitless options, but infinite choice might actually be paralyzing our ability to make decisions and find satisfaction. David Epstein, bestselling author of Range and the new book Inside the Box, joins host Zachary Karabell to argue that we severely overvalue complete freedom. Instead, Epstein reveals how imposing limits and constraints on ourselves can act as a powerful tool to drive creativity, spur innovati...
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Researchers just used machine learning to read a carbonized Roman scroll that hasn't been opened in 2,000 years. In this week’s progress report, Emma Varvaloucas dives into a technological breakthrough that is unlocking an ancient library buried by volcanic ash in 79 AD.
Plus: a groundbreaking medical device in Barcelona that extends the viability of human eyes for vital medical research, the rapid adoption of eco-frie...
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July 15, 2026 • 42 mins
The American criminal justice system is often viewed as an unfixable and intractable problem. But shifting demographics and new approaches to community investment might actually bring a natural end to the era of mass incarceration.Alex Duran spent 12 years in New York maximum security prisons before earning a liberal arts degree through the Bard College Prison Initiative. Today, he leads the criminal justice portfolio at Galaxy Giv...
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