Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:01):
One more time for the weather. Real quick here today
and tomorrow mostly sunny, highest seventy five in between overnight
little forty two with clear skies. Wednesday night's going to
be partly tied with a low forty five and seventy
five to high again on Thursday, but it comes along
with clouds forty seven. Now let's hear the final traffic.
Speaker 2 (00:15):
From the UCLP Traumphing Center. When it comes to stroke,
every second counts. That's why the UC Health Comprehensive Stroke
Center is clear choice for wrap up life saving treatment.
Learn more at uce health dot com. Rex clear in
Bend seventy four near Montana, traffic still a bit heavy
from above the Montana rant of the seventy five ramp.
South Bend seventy five continues slow in and out of
(00:36):
Blackland as southbound seventy one heaviest between two seventy five
and Red Paint. There's some wreck on Montgomery up Leicester
and pleasant Ridge chuck Ingramont fifty five KR. See the
talk station.
Speaker 1 (00:50):
A forty six fifty five krc DE talk station. Time
for some education sc expert. Today we've got doctor James
Essel The return of Doctor James SLH my cancer doctors,
ohcs A heematologists, medical oncologists, blood and bone mara transplant
specialists and cellular therapy expert. One of the fine physicians
you'll find at OHC, which you can find online at
(01:11):
ohcare dot com or call eight eight eight six four
ninety eight hundred doctor Assello. Great to have you in studio.
Speaker 3 (01:17):
Today, Brian.
Speaker 1 (01:19):
There's a month for everything, and this March is multiple
myloma Awareness months start by talking about what is multiple
myloma and what are the risk factors for it.
Speaker 3 (01:29):
So, multi myloma is a hematological malignancy. Basically plasma cells
that make antibodies, you know, the vaccines, infection, so forth.
Those plasma cells can go wild and cause a cancer.
The symptoms of it, these plasma cells can get in
and dissolve the bone. They don't cause pain, but it
(01:50):
can cause fractures that can cause the calcium to go high.
It can be detected with a routine visit to a doctor.
You don't have to be looking specifically for myeloma. Seeing
the calcium and the protein and subtle hints can help out. Wow,
catching it early.
Speaker 1 (02:06):
Now, obviously this is a cancer. Can it spread metastasize
that kind of thing.
Speaker 3 (02:11):
This typically can affect the bone marrow, so your blood
counts can be low, but it can go to the bones,
cause broken bones can cause kidney failure. So catching it
early is really important. It's very very treatable if it's
caught early.
Speaker 1 (02:24):
Well, that's good to hear. So what should people be
looking for the signs and symptoms to make sure that
they can get out of this?
Speaker 3 (02:31):
Really fatigue, there's bone pain possibly, but it's really get
a routine test with your doctor.
Speaker 1 (02:38):
That's it.
Speaker 3 (02:39):
Yeah, that's the main thing.
Speaker 1 (02:40):
You say, asked for it?
Speaker 3 (02:41):
Well, no, if you go in the test that they
get where they get your chemistries, CBC cmp is can
be picked up.
Speaker 1 (02:49):
Oh that's convenient because hell we all get those. I'll
get like four of the years exactly. Yeah, well I'm
under your guys care. So what are now? We always
talk about treatments. You sound like there seem to be
a sense of you know, a note of optimism your
voice that you know you get ahead of this, and
there are treatments for it? What do they involve? What
do they include? So?
Speaker 3 (03:07):
I saw a patient a few months ago who told me,
you know, I first saw you told me this about
five years to live and she's at fifteen years now,
so things that will really changed and not continuous terrible
chemotherapy the whole time. The new treatments, like we've talked
about Brian in the past, are the immune treatments. Carti
now for myeloma is now approved in the second line,
(03:28):
so first relapse, and we're looking at the using the
immune system to find a target in this case is
called BCMA B cell maturation andagen, and we have Cartie.
We have what's called byte therapy against that. But when
that quits working, what do you do next? Well, now
there's a new target called gpr C five D, which
(03:49):
long long term. But when we use a bispecific in
other words, use an antibody that pulls T cells to
that cancer over a long period of time, it caused
a lot of horrible side effects. Bad tastes in your mouth,
skin problems, nail problems. It's kind of nasty and people
may be in remission have to quit it because the
side effects. Oh wow, we're pioneering a car tee and
(04:10):
the first patient's coming up I believe this week, where
instead of having this long exposure and getting these side effects.
They get all the cells at one time with the
infusion of chimerican asine receptor T cells made from the
patient's own blood put back in, so they only exposed
to that for about a month, go into a deep
long laster and remission without the side effects. And that's
(04:31):
after they've already been through cartis. So you know, people
that have this, we don't have a cure right now,
but they can live for a very long time.
Speaker 1 (04:39):
Well that's very good news. Now, these are bespoke treatments. Correct,
This isn't something you get off the shelf. Uh no, Okay,
So how long does the treatment protocol go then, and
how long does it take to build these cancer treatments,
these bespoke treatments.
Speaker 3 (04:54):
Well, the typical person gets kind of an oral combination
of a monoclonal antibody like you're getting with an oral
for about four months ago into permission. Then they'll get
an AUTAUGAUS stem cell transplant hidros chemotherapy, which is fairly toxic, yes,
And then after that they're on a maintenance pill and
that usually goes for about five years. At that point,
(05:17):
then cartie would be involved, and then after that's going
to buy you another couple of years. Then after that fails,
maybe buy specific therapy for another couple of years, and
we can just keep adding these on at this point.
Speaker 1 (05:29):
Wow, so it's very long term. Yeah, well it's ansors.
Speaker 3 (05:33):
It's long term, and because of that reason, side effects
are critically important. So we're always looking at doing a
better job from an efficacy standpoint, but also make it tolerable.
Speaker 1 (05:44):
I have to ask you this because you and I
exchange a couple of words about RFK, you know, bringing
health to our attention and making an effort to get
better foods, better diets, get rid of the chemicals, the
additives to for all of our collective health benefit. How
important in cancer generally speaking is diet?
Speaker 3 (06:03):
You know, I don't think anybody knows, but if you
look at when we were kids, you know, first of all,
nobody went out to eat. You couldn't afford to, and
there weren't all the restaurants. The food was sourced locally.
He went to the local butcher shop. Now you go
to the supermarket and the beefs from all over the place.
So there's been a change, and clearly we see younger
(06:23):
people getting cancer earlier. How much of its diet. How
much of it's some other environmentally, but I think diet
clearly is part of it.
Speaker 1 (06:31):
Well, Okay, I kind of felt that way as well,
because the abundance of sugars in our diets, and I've
been reading so much about sugar and its impact on
our health and having cut the sugar out. I always
just use this an opportunity just to tell people give
it a try, because you'll feel a hell of a
lot better.
Speaker 3 (06:47):
Plus treat your diabetes and your hypertension and cardiac disease
and all those tuff well didn't have any right well,
but it keeps you from getting it, yeah, yeah, yeah.
Speaker 1 (06:55):
So in terms of clinical trials, I think you might
have just gone over it already, but I know you're
always doing clinical trials, OHC. And you know, folks you
got cancer, you know, get a second opinion if you're
already being treated by someone, or make sure you're on
the cutting edge with with these clinical trials, because that's
where it's all happening. So those would be the carte
and byte therapies you talk about.
Speaker 3 (07:14):
We also have some from maintenance therapy that you know,
if you're happy with where we are in cancer, therapy,
don't go on a clinical trial, but nobody's happy. You
want to do better, you want to have less talks,
to steal of longer, and people think, oh, I don't
want a placebo. There's no placebo in these. You get
standard of care versus something we believe will be better.
And you're followed closer than you would be off of
a clinical trial. So if there is a side effect,
(07:37):
it's cotter early and we'd close the trial. But I
a strong believer. That's what that's how we make progress.
Speaker 1 (07:42):
Well, and that's how you've gotten to this point exactly.
I mean cart was they went through some clinical trials
on that, and that's the information you have given me
over the years, and the other OAHC doctors have on that.
I just find it truly amazing. I mean, you have
eliminated some very difficult cancers just with this carteeth their.
Speaker 3 (08:01):
Correct, right. I mean it's using your body, using your
own immune system, getting away from chemotherapy. That's where everything's going.
Speaker 1 (08:10):
Yeah, and there are some significant downsides of chemotherapy. I
know that, all right, doctor? Any other words on multiple
my loma, just a couple things.
Speaker 3 (08:18):
This is usually a disease you know, kind of upper
sixties when it starts, but we do see younger people.
There's an increase in your African American listeners. They should
definitely be thinking about, you know, being checked as far
as environmental. For the veterans that listen to your show,
this is an agent orange related cancer, so all the
Vietnam vets you know, should be thinking about this too well.
Speaker 1 (08:40):
I'd like to hope since they get via medical care,
that they are getting that blood panel that we talked about,
so they will know ahead early on in the game
if their numbers reflected, that might be a possibility, right,
doctor James Essel. It has been a great conversation. I
always appreciate the work that you're doing at OHC, and
I feel that I am in great hands getting my
treatment there. To reach OHC again online ohcare dot com,
(09:02):
ohcare dot com. The number to call eight eight eight
sixty eight hundred. That's eight eight eight six forty eight hundred,
doctor as well. Keep up the great work, sir, Thank you,
thanks for all the work you're doing for my listeners
as well. Folks, you can get a chance to listen
live Todd Zinzer eye opening conversation about the city government,
City of Cincinnati government, former Inspector General and host of
(09:23):
the Citizen Watchdog podcast. Check out my that podcast on
my podcast page fifty five care sea dot com. Enlightening
It is also maybe having revealed some potential for corruption
inside scoop with Breitbart reporter Randy Clark on the situation
at the Southern border, and of course the Daniel Davis
Deep Dive with the latest on Ukraine and Russia. Tune
in tomorrow Jack Atherton Congressman Thomas Massey getting an earful
(09:46):
from Donald Trump yesterday, plus Judge and an Apolotan a
libity tomorrow. If a wonderful day, folks. Thanks to Joe
Strekker for producing the program. And don't go away, clembeck
is next. News happens fast, Stay up to date at
the top of the hour, moving very quickly. Fifty five
KRC the talk station.
Speaker 2 (10:04):
This
One more time for the weather. Real quick here today
and tomorrow mostly sunny, highest seventy five in between overnight
little forty two with clear skies. Wednesday night's going to
be partly tied with a low forty five and seventy
five to high again on Thursday, but it comes along
with clouds forty seven. Now let's hear the final traffic.
Speaker 2 (00:15):
From the UCLP Traumphing Center. When it comes to stroke,
every second counts. That's why the UC Health Comprehensive Stroke
Center is clear choice for wrap up life saving treatment.
Learn more at uce health dot com. Rex clear in
Bend seventy four near Montana, traffic still a bit heavy
from above the Montana rant of the seventy five ramp.
South Bend seventy five continues slow in and out of
(00:36):
Blackland as southbound seventy one heaviest between two seventy five
and Red Paint. There's some wreck on Montgomery up Leicester
and pleasant Ridge chuck Ingramont fifty five KR. See the
talk station.
Speaker 1 (00:50):
A forty six fifty five krc DE talk station. Time
for some education sc expert. Today we've got doctor James
Essel The return of Doctor James SLH my cancer doctors,
ohcs A heematologists, medical oncologists, blood and bone mara transplant
specialists and cellular therapy expert. One of the fine physicians
you'll find at OHC, which you can find online at
(01:11):
ohcare dot com or call eight eight eight six four
ninety eight hundred doctor Assello. Great to have you in studio.
Speaker 3 (01:17):
Today, Brian.
Speaker 1 (01:19):
There's a month for everything, and this March is multiple
myloma Awareness months start by talking about what is multiple
myloma and what are the risk factors for it.
Speaker 3 (01:29):
So, multi myloma is a hematological malignancy. Basically plasma cells
that make antibodies, you know, the vaccines, infection, so forth.
Those plasma cells can go wild and cause a cancer.
The symptoms of it, these plasma cells can get in
and dissolve the bone. They don't cause pain, but it
(01:50):
can cause fractures that can cause the calcium to go high.
It can be detected with a routine visit to a doctor.
You don't have to be looking specifically for myeloma. Seeing
the calcium and the protein and subtle hints can help out. Wow,
catching it early.
Speaker 1 (02:06):
Now, obviously this is a cancer. Can it spread metastasize
that kind of thing.
Speaker 3 (02:11):
This typically can affect the bone marrow, so your blood
counts can be low, but it can go to the bones,
cause broken bones can cause kidney failure. So catching it
early is really important. It's very very treatable if it's
caught early.
Speaker 1 (02:24):
Well, that's good to hear. So what should people be
looking for the signs and symptoms to make sure that
they can get out of this?
Speaker 3 (02:31):
Really fatigue, there's bone pain possibly, but it's really get
a routine test with your doctor.
Speaker 1 (02:38):
That's it.
Speaker 3 (02:39):
Yeah, that's the main thing.
Speaker 1 (02:40):
You say, asked for it?
Speaker 3 (02:41):
Well, no, if you go in the test that they
get where they get your chemistries, CBC cmp is can
be picked up.
Speaker 1 (02:49):
Oh that's convenient because hell we all get those. I'll
get like four of the years exactly. Yeah, well I'm
under your guys care. So what are now? We always
talk about treatments. You sound like there seem to be
a sense of you know, a note of optimism your
voice that you know you get ahead of this, and
there are treatments for it? What do they involve? What
do they include? So?
Speaker 3 (03:07):
I saw a patient a few months ago who told me,
you know, I first saw you told me this about
five years to live and she's at fifteen years now,
so things that will really changed and not continuous terrible
chemotherapy the whole time. The new treatments, like we've talked
about Brian in the past, are the immune treatments. Carti
now for myeloma is now approved in the second line,
(03:28):
so first relapse, and we're looking at the using the
immune system to find a target in this case is
called BCMA B cell maturation andagen, and we have Cartie.
We have what's called byte therapy against that. But when
that quits working, what do you do next? Well, now
there's a new target called gpr C five D, which
(03:49):
long long term. But when we use a bispecific in
other words, use an antibody that pulls T cells to
that cancer over a long period of time, it caused
a lot of horrible side effects. Bad tastes in your mouth,
skin problems, nail problems. It's kind of nasty and people
may be in remission have to quit it because the
side effects. Oh wow, we're pioneering a car tee and
(04:10):
the first patient's coming up I believe this week, where
instead of having this long exposure and getting these side effects.
They get all the cells at one time with the
infusion of chimerican asine receptor T cells made from the
patient's own blood put back in, so they only exposed
to that for about a month, go into a deep
long laster and remission without the side effects. And that's
(04:31):
after they've already been through cartis. So you know, people
that have this, we don't have a cure right now,
but they can live for a very long time.
Speaker 1 (04:39):
Well that's very good news. Now, these are bespoke treatments. Correct,
This isn't something you get off the shelf. Uh no, Okay,
So how long does the treatment protocol go then, and
how long does it take to build these cancer treatments,
these bespoke treatments.
Speaker 3 (04:54):
Well, the typical person gets kind of an oral combination
of a monoclonal antibody like you're getting with an oral
for about four months ago into permission. Then they'll get
an AUTAUGAUS stem cell transplant hidros chemotherapy, which is fairly toxic, yes,
And then after that they're on a maintenance pill and
that usually goes for about five years. At that point,
(05:17):
then cartie would be involved, and then after that's going
to buy you another couple of years. Then after that fails,
maybe buy specific therapy for another couple of years, and
we can just keep adding these on at this point.
Speaker 1 (05:29):
Wow, so it's very long term. Yeah, well it's ansors.
Speaker 3 (05:33):
It's long term, and because of that reason, side effects
are critically important. So we're always looking at doing a
better job from an efficacy standpoint, but also make it tolerable.
Speaker 1 (05:44):
I have to ask you this because you and I
exchange a couple of words about RFK, you know, bringing
health to our attention and making an effort to get
better foods, better diets, get rid of the chemicals, the
additives to for all of our collective health benefit. How
important in cancer generally speaking is diet?
Speaker 3 (06:03):
You know, I don't think anybody knows, but if you
look at when we were kids, you know, first of all,
nobody went out to eat. You couldn't afford to, and
there weren't all the restaurants. The food was sourced locally.
He went to the local butcher shop. Now you go
to the supermarket and the beefs from all over the place.
So there's been a change, and clearly we see younger
(06:23):
people getting cancer earlier. How much of its diet. How
much of it's some other environmentally, but I think diet
clearly is part of it.
Speaker 1 (06:31):
Well, Okay, I kind of felt that way as well,
because the abundance of sugars in our diets, and I've
been reading so much about sugar and its impact on
our health and having cut the sugar out. I always
just use this an opportunity just to tell people give
it a try, because you'll feel a hell of a
lot better.
Speaker 3 (06:47):
Plus treat your diabetes and your hypertension and cardiac disease
and all those tuff well didn't have any right well,
but it keeps you from getting it, yeah, yeah, yeah.
Speaker 1 (06:55):
So in terms of clinical trials, I think you might
have just gone over it already, but I know you're
always doing clinical trials, OHC. And you know, folks you
got cancer, you know, get a second opinion if you're
already being treated by someone, or make sure you're on
the cutting edge with with these clinical trials, because that's
where it's all happening. So those would be the carte
and byte therapies you talk about.
Speaker 3 (07:14):
We also have some from maintenance therapy that you know,
if you're happy with where we are in cancer, therapy,
don't go on a clinical trial, but nobody's happy. You
want to do better, you want to have less talks,
to steal of longer, and people think, oh, I don't
want a placebo. There's no placebo in these. You get
standard of care versus something we believe will be better.
And you're followed closer than you would be off of
a clinical trial. So if there is a side effect,
(07:37):
it's cotter early and we'd close the trial. But I
a strong believer. That's what that's how we make progress.
Speaker 1 (07:42):
Well, and that's how you've gotten to this point exactly.
I mean cart was they went through some clinical trials
on that, and that's the information you have given me
over the years, and the other OAHC doctors have on that.
I just find it truly amazing. I mean, you have
eliminated some very difficult cancers just with this carteeth their.
Speaker 3 (08:01):
Correct, right. I mean it's using your body, using your
own immune system, getting away from chemotherapy. That's where everything's going.
Speaker 1 (08:10):
Yeah, and there are some significant downsides of chemotherapy. I
know that, all right, doctor? Any other words on multiple
my loma, just a couple things.
Speaker 3 (08:18):
This is usually a disease you know, kind of upper
sixties when it starts, but we do see younger people.
There's an increase in your African American listeners. They should
definitely be thinking about, you know, being checked as far
as environmental. For the veterans that listen to your show,
this is an agent orange related cancer, so all the
Vietnam vets you know, should be thinking about this too well.
Speaker 1 (08:40):
I'd like to hope since they get via medical care,
that they are getting that blood panel that we talked about,
so they will know ahead early on in the game
if their numbers reflected, that might be a possibility, right,
doctor James Essel. It has been a great conversation. I
always appreciate the work that you're doing at OHC, and
I feel that I am in great hands getting my
treatment there. To reach OHC again online ohcare dot com,
(09:02):
ohcare dot com. The number to call eight eight eight
sixty eight hundred. That's eight eight eight six forty eight hundred,
doctor as well. Keep up the great work, sir, Thank you,
thanks for all the work you're doing for my listeners
as well. Folks, you can get a chance to listen
live Todd Zinzer eye opening conversation about the city government,
City of Cincinnati government, former Inspector General and host of
(09:23):
the Citizen Watchdog podcast. Check out my that podcast on
my podcast page fifty five care sea dot com. Enlightening
It is also maybe having revealed some potential for corruption
inside scoop with Breitbart reporter Randy Clark on the situation
at the Southern border, and of course the Daniel Davis
Deep Dive with the latest on Ukraine and Russia. Tune
in tomorrow Jack Atherton Congressman Thomas Massey getting an earful
(09:46):
from Donald Trump yesterday, plus Judge and an Apolotan a
libity tomorrow. If a wonderful day, folks. Thanks to Joe
Strekker for producing the program. And don't go away, clembeck
is next. News happens fast, Stay up to date at
the top of the hour, moving very quickly. Fifty five
KRC the talk station.
Speaker 2 (10:04):
This
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