Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:02):
One more time for the nine first wenty Weatherhork casts.
Today we're in the middle of the snow advisory till
tomorrow morning at seven am, and snow probably in northern
Kentucky for the most part. May see two or three
inches in some areas less as you move north. Today's
high thirty three, over night low of twenty nine. Tomorrow
we'll see high forty one. It'll be dried to start
the day, but later in the afternoon evening they'd say
some showers could show up, maybe a snow rain mix.
(00:24):
Over night low on Tomorrow night twenty eight and thirty
three is going to be the high on Thursday, with
partly fidy skies closing out of thirty four degrees. Time
for final traffic Chuck Ingram from the UCL Tramphing Center.
Speaker 2 (00:35):
For more than two hundred years, the experts at UC
Health I've been giving heard patients and chance from better outcomes.
That's boundless care. You can trust expect more at U
see help dot com cruise continue to work with an
accident in westbound seventy four. It's a two seventy five
at the coal rings.
Speaker 3 (00:50):
Split will left side's blocked, so you have to go
all the way over to the right shoulder in order
to get by southbound seventy five slows through Walkland Kingram
On fifty five krc the talk station.
Speaker 1 (01:06):
Forty four or a fifty five KRCD talk station. Happy Tuesday,
Great day to be tuned in, perfect time to be
tuned in. You probably have been impacted by cancer some way,
shape or form, and I think everybody knows somebody who's
having to deal with cancer, and my listeners all know
that I'm dealing with lymphoma. And my doctors are OHC
so happy to be in their hands and provide a
(01:26):
wonderful care and treatment for me over the years, and
I feel well. I'm always uplifted and positive to talk
to the doctors from OHC because they're always giving me
good news about new treatment protocols and exciting things that
are happening, and most notably in the area of clinical trials,
and they're really big. They're doing clinical trials all the
time at OHC. To learn more or get a second opinion,
(01:47):
their phone number is eight eight eight six four ninety
eight hundred. You find them online at ohcare dot com.
And I'm pleased to have in studio doctor Jadev Metu
to talk about the clinical trials. Doctor Metwu is a
medical oncologist and hematologist. Good to have you in studio, doctor, good.
Speaker 4 (02:01):
Morning, Thank you for having me.
Speaker 1 (02:02):
Got exciting news for my listening audience today. I bet
clinical trials, that's the way now. I always like to
establish that when you're in a clinical trial, and I've
heard this before, so I don't think I'm going to
say something that's not right here. You're not like a
lab rat. You know, this isn't just some brand new
out of the gate. You know we're going to use
you as to experiment on kind of thing, right.
Speaker 4 (02:24):
Absolutely not. So for the most part, when people participate
in clinical trials, people are randomized to either the standard
of care, and most clinical trials the goal for that
is to improve on the standard of care. So a
lot of times you have people who are going to
get what would be recommended by the NCCN or National
(02:45):
Comprehensive Cancer Network, and on the clinical trial ARM is
typically an investigational agent which is hoping to improve on that.
Speaker 1 (02:54):
Okay, so the treatment I got retuxin sitting there, I
get a drip bag and that's what I got. A
clinical trial would be retucin, which is the standard of
care for the lomfoma, plus another.
Speaker 4 (03:09):
Drug typically yes, or sometimes a completely new drug altogether.
Oh really, which would be compared against retuxin for example,
to try and improve or better retucin.
Speaker 1 (03:23):
Okay, fair enough, that makes sense. So the benefits of
being in a clinical trial specifically.
Speaker 4 (03:29):
So plenty of benefits, Like we just mentioned, receiving cutting
edge care often not available anywhere else. Typically when you're
on a trial, there's a very stringent schedule, so you
get extra labs imaging, and that could put you at
peace of mind. And at the end of the day,
(03:50):
the whole goal is to advance research and help someone
else down the line. So participating in a clinical trial
is the way medicine will advance and hope help someone.
Speaker 1 (04:01):
Help and save the world, one clinical trial at a time.
How does OHC handle cancer research for their cancer patients?
Speaker 4 (04:07):
So any person who walks through the door and has
a cancer diagnosis is typically screened for clinical trials. We
educate our patients on the availability of their trials, whether
they'd be eligible or not, and what are the benefits
and risks associated with that, And that's how we talk
(04:29):
to them about the trials and see if they qualify
for them.
Speaker 1 (04:32):
Qualify, and then a form of informed consent by giving
them all the information they have the option of like Okay, yes,
that sounds like a good idea for me, or no,
I want to go with just the plan on standard
of care treatment? Absolutely great. Now what are the This
is where we get the good part. What are the
newest trials that people need to know about that are
going on? There? These cutting edge treatments.
Speaker 4 (04:53):
So just a few examples, we have the Flamingo breast
cancer vaccine.
Speaker 1 (04:58):
Trial Flamingo, Yes, after the bird. Correct, how did you
get that name? You should ask the trial.
Speaker 4 (05:07):
We have what's called an Alpha three trial or to
check for minimal residual disease and cancer results. We have
multiple byte therapy trials and carte cell trials. But what's
important to note is OITC is associated with Sartacanan Research Institute,
so that by virtue gives us access to actually hundreds
(05:29):
of trials across the network. And based on the screening
process we just talk, we can actually start even a
single patient on one of those trials.
Speaker 1 (05:41):
If huh, then you're consolidating the data with other single
individuals out there around that are doing the same protocol.
Speaker 4 (05:50):
Correct. So for the most part, these are multinational trials
across the globe. Depends upon how advanced agent is and
how many patients they're looking to a true, but it
can be all across America and sometimes all across the
world where they're trying to accrue patients for these trials.
Speaker 1 (06:07):
So that shared that's a really interesting component because it
seems like often medicine is a closed You don't want
to share what the information is. You want to be
the only one in the block that has this specific
treatment because of course that benefits you from a profit standpoint,
But you're sharing all this collective data with everybody else. Absolutely, Yes,
that's a wonderful concept. Now, I got to go back
(06:27):
to this alpha alpha three MRD test check for residual
cancer cells. Is that sort of like after you've been
through treatment, you have you might have cancer still floating
around in your body?
Speaker 4 (06:39):
Correct, So basically we're looking for cancer DNA specifically, and
we've advanced in testing to be able to actually pick
that up.
Speaker 1 (06:50):
Okay, because that may lead to someone the cancer reoccurring possibly, Yes, Okay,
all right, and I go back to what's the flamingo
breast cancer VAC. How is this a different treatment protocol
and does it work for later stage breast cancer?
Speaker 4 (07:06):
So it's actually in patients who've already been treated for
breast cancer and doing well. And this is compared to
observation and from the data we have at least at
this time being patients on the trial are doing better,
but more to come, all.
Speaker 1 (07:22):
Right, and then cart that's sort of the designer like
they check your genetics and they create an agent that
targets your specific type of cancer in your body. If
I got that right. I've heard a lot about these
over the years, and sometimes I get the different types
of treatments.
Speaker 4 (07:41):
So briefly speaking, we actually harvest a patient's own tea celts.
Then those actually go to a lab, they're modified to
target the cancer cells, and after that we reinfuse the
patient's own T cells to fight the cancer.
Speaker 1 (07:59):
Is that a long process to do that?
Speaker 4 (08:01):
It can be a few weeks's yes, that's one of
the things that they're looking to improve on is the
time between harvesting and giving to patients the treatment.
Speaker 1 (08:11):
But you know, in the grand scheme of things, weeks
is not that long. If you're getting this tailored drug
or tailored treatment and the results have been, from what
I understand, pretty astounding. Yes, well that's good news right there.
Why does everybody care about clinical trials for cancer?
Speaker 4 (08:30):
Because of the prevalence of cancer, everyone will at some
point encounter it, whether it's themselves, their parents, their family members,
a friend, or maybe even a coworker. So it's important
that they know what their options are for treatment, and
one of those options includes clinical trials, and it should
(08:51):
be an automatic step to research what trials are available.
And also at OC as well, that's just a part
of how we provide care to our patients.
Speaker 1 (09:01):
All right, Well, you obviously save lives at OHC, and
I think that has got to be a real inspiration
for you to come to work every day, because I've
been in the treatment room for my bag and it
is a quite depressing environment, sir, and I always looked
around me and I thought, you know what, I think
(09:21):
I probably hit the lottery of cancers. Given that it's lymphoma,
I don't have to worry about metastisation. And I look
arouns across the room and I see some poor woman
there getting four different bags. You know, she's lost her
hair because of the irradiation treatment, and it's just it's
sad to see. I know you're doing great work there,
but boy, that's got to be a tough thing. Get
up and go to bed when you know you're dealing
(09:42):
with literally you're dealing with death.
Speaker 4 (09:44):
Yeah. Absolutely, it's not easy no matter how long you
do it. It never gets easy to give a patient
like a terminal diagnosis and things on those lines. But
that's kind of the whole goal of research, right, A
goal is to kind of beat.
Speaker 1 (10:01):
Cancer and put yourself out of business.
Speaker 4 (10:04):
Well, I wouldn't be unhappy about that.
Speaker 1 (10:07):
Yeah, I see. I knew you're gonna say that, because
you're smart, you're obviously a brilliant doctor, and you'll find
something else to do if you cure cancer. So yeah,
that's that's okay with me. I think that's wonderful. Okay, Well,
I'll tell you what. It's been a fascinating conversation on
clinical Piles about trials with doctor jeddev Matt two, one
of the excellent doctors at OHC, and uh, do me
(10:28):
a favorite. Tell doctor Patel that Brian said, Hi, if
you run into Waterhouse, tell doctor Waterhouse Brian said, Hi too.
Those are wonderful, wonderful folks. So if you need a
second opinion, if you've got cancer and you're concerned about
the level of care you're getting, maybe you want to
want to look into one of these clinical trials. OHC
is doing them all the time. It's eight eight eight
six eight hundred eight eight eight sixty eight hundred online
(10:52):
ohcare dot com.
One more time for the nine first wenty Weatherhork casts.
Today we're in the middle of the snow advisory till
tomorrow morning at seven am, and snow probably in northern
Kentucky for the most part. May see two or three
inches in some areas less as you move north. Today's
high thirty three, over night low of twenty nine. Tomorrow
we'll see high forty one. It'll be dried to start
the day, but later in the afternoon evening they'd say
some showers could show up, maybe a snow rain mix.
(00:24):
Over night low on Tomorrow night twenty eight and thirty
three is going to be the high on Thursday, with
partly fidy skies closing out of thirty four degrees. Time
for final traffic Chuck Ingram from the UCL Tramphing Center.
Speaker 2 (00:35):
For more than two hundred years, the experts at UC
Health I've been giving heard patients and chance from better outcomes.
That's boundless care. You can trust expect more at U
see help dot com cruise continue to work with an
accident in westbound seventy four. It's a two seventy five
at the coal rings.
Speaker 3 (00:50):
Split will left side's blocked, so you have to go
all the way over to the right shoulder in order
to get by southbound seventy five slows through Walkland Kingram
On fifty five krc the talk station.
Speaker 1 (01:06):
Forty four or a fifty five KRCD talk station. Happy Tuesday,
Great day to be tuned in, perfect time to be
tuned in. You probably have been impacted by cancer some way,
shape or form, and I think everybody knows somebody who's
having to deal with cancer, and my listeners all know
that I'm dealing with lymphoma. And my doctors are OHC
so happy to be in their hands and provide a
(01:26):
wonderful care and treatment for me over the years, and
I feel well. I'm always uplifted and positive to talk
to the doctors from OHC because they're always giving me
good news about new treatment protocols and exciting things that
are happening, and most notably in the area of clinical trials,
and they're really big. They're doing clinical trials all the
time at OHC. To learn more or get a second opinion,
(01:47):
their phone number is eight eight eight six four ninety
eight hundred. You find them online at ohcare dot com.
And I'm pleased to have in studio doctor Jadev Metu
to talk about the clinical trials. Doctor Metwu is a
medical oncologist and hematologist. Good to have you in studio, doctor, good.
Speaker 4 (02:01):
Morning, Thank you for having me.
Speaker 1 (02:02):
Got exciting news for my listening audience today. I bet
clinical trials, that's the way now. I always like to
establish that when you're in a clinical trial, and I've
heard this before, so I don't think I'm going to
say something that's not right here. You're not like a
lab rat. You know, this isn't just some brand new
out of the gate. You know we're going to use
you as to experiment on kind of thing, right.
Speaker 4 (02:24):
Absolutely not. So for the most part, when people participate
in clinical trials, people are randomized to either the standard
of care, and most clinical trials the goal for that
is to improve on the standard of care. So a
lot of times you have people who are going to
get what would be recommended by the NCCN or National
(02:45):
Comprehensive Cancer Network, and on the clinical trial ARM is
typically an investigational agent which is hoping to improve on that.
Speaker 1 (02:54):
Okay, so the treatment I got retuxin sitting there, I
get a drip bag and that's what I got. A
clinical trial would be retucin, which is the standard of
care for the lomfoma, plus another.
Speaker 4 (03:09):
Drug typically yes, or sometimes a completely new drug altogether.
Oh really, which would be compared against retuxin for example,
to try and improve or better retucin.
Speaker 1 (03:23):
Okay, fair enough, that makes sense. So the benefits of
being in a clinical trial specifically.
Speaker 4 (03:29):
So plenty of benefits, Like we just mentioned, receiving cutting
edge care often not available anywhere else. Typically when you're
on a trial, there's a very stringent schedule, so you
get extra labs imaging, and that could put you at
peace of mind. And at the end of the day,
(03:50):
the whole goal is to advance research and help someone
else down the line. So participating in a clinical trial
is the way medicine will advance and hope help someone.
Speaker 1 (04:01):
Help and save the world, one clinical trial at a time.
How does OHC handle cancer research for their cancer patients?
Speaker 4 (04:07):
So any person who walks through the door and has
a cancer diagnosis is typically screened for clinical trials. We
educate our patients on the availability of their trials, whether
they'd be eligible or not, and what are the benefits
and risks associated with that, And that's how we talk
(04:29):
to them about the trials and see if they qualify
for them.
Speaker 1 (04:32):
Qualify, and then a form of informed consent by giving
them all the information they have the option of like Okay, yes,
that sounds like a good idea for me, or no,
I want to go with just the plan on standard
of care treatment? Absolutely great. Now what are the This
is where we get the good part. What are the
newest trials that people need to know about that are
going on? There? These cutting edge treatments.
Speaker 4 (04:53):
So just a few examples, we have the Flamingo breast
cancer vaccine.
Speaker 1 (04:58):
Trial Flamingo, Yes, after the bird. Correct, how did you
get that name? You should ask the trial.
Speaker 4 (05:07):
We have what's called an Alpha three trial or to
check for minimal residual disease and cancer results. We have
multiple byte therapy trials and carte cell trials. But what's
important to note is OITC is associated with Sartacanan Research Institute,
so that by virtue gives us access to actually hundreds
(05:29):
of trials across the network. And based on the screening
process we just talk, we can actually start even a
single patient on one of those trials.
Speaker 1 (05:41):
If huh, then you're consolidating the data with other single
individuals out there around that are doing the same protocol.
Speaker 4 (05:50):
Correct. So for the most part, these are multinational trials
across the globe. Depends upon how advanced agent is and
how many patients they're looking to a true, but it
can be all across America and sometimes all across the
world where they're trying to accrue patients for these trials.
Speaker 1 (06:07):
So that shared that's a really interesting component because it
seems like often medicine is a closed You don't want
to share what the information is. You want to be
the only one in the block that has this specific
treatment because of course that benefits you from a profit standpoint,
But you're sharing all this collective data with everybody else. Absolutely, Yes,
that's a wonderful concept. Now, I got to go back
(06:27):
to this alpha alpha three MRD test check for residual
cancer cells. Is that sort of like after you've been
through treatment, you have you might have cancer still floating
around in your body?
Speaker 4 (06:39):
Correct, So basically we're looking for cancer DNA specifically, and
we've advanced in testing to be able to actually pick
that up.
Speaker 1 (06:50):
Okay, because that may lead to someone the cancer reoccurring possibly, Yes, Okay,
all right, and I go back to what's the flamingo
breast cancer VAC. How is this a different treatment protocol
and does it work for later stage breast cancer?
Speaker 4 (07:06):
So it's actually in patients who've already been treated for
breast cancer and doing well. And this is compared to
observation and from the data we have at least at
this time being patients on the trial are doing better,
but more to come, all.
Speaker 1 (07:22):
Right, and then cart that's sort of the designer like
they check your genetics and they create an agent that
targets your specific type of cancer in your body. If
I got that right. I've heard a lot about these
over the years, and sometimes I get the different types
of treatments.
Speaker 4 (07:41):
So briefly speaking, we actually harvest a patient's own tea celts.
Then those actually go to a lab, they're modified to
target the cancer cells, and after that we reinfuse the
patient's own T cells to fight the cancer.
Speaker 1 (07:59):
Is that a long process to do that?
Speaker 4 (08:01):
It can be a few weeks's yes, that's one of
the things that they're looking to improve on is the
time between harvesting and giving to patients the treatment.
Speaker 1 (08:11):
But you know, in the grand scheme of things, weeks
is not that long. If you're getting this tailored drug
or tailored treatment and the results have been, from what
I understand, pretty astounding. Yes, well that's good news right there.
Why does everybody care about clinical trials for cancer?
Speaker 4 (08:30):
Because of the prevalence of cancer, everyone will at some
point encounter it, whether it's themselves, their parents, their family members,
a friend, or maybe even a coworker. So it's important
that they know what their options are for treatment, and
one of those options includes clinical trials, and it should
(08:51):
be an automatic step to research what trials are available.
And also at OC as well, that's just a part
of how we provide care to our patients.
Speaker 1 (09:01):
All right, Well, you obviously save lives at OHC, and
I think that has got to be a real inspiration
for you to come to work every day, because I've
been in the treatment room for my bag and it
is a quite depressing environment, sir, and I always looked
around me and I thought, you know what, I think
(09:21):
I probably hit the lottery of cancers. Given that it's lymphoma,
I don't have to worry about metastisation. And I look
arouns across the room and I see some poor woman
there getting four different bags. You know, she's lost her
hair because of the irradiation treatment, and it's just it's
sad to see. I know you're doing great work there,
but boy, that's got to be a tough thing. Get
up and go to bed when you know you're dealing
(09:42):
with literally you're dealing with death.
Speaker 4 (09:44):
Yeah. Absolutely, it's not easy no matter how long you
do it. It never gets easy to give a patient
like a terminal diagnosis and things on those lines. But
that's kind of the whole goal of research, right, A
goal is to kind of beat.
Speaker 1 (10:01):
Cancer and put yourself out of business.
Speaker 4 (10:04):
Well, I wouldn't be unhappy about that.
Speaker 1 (10:07):
Yeah, I see. I knew you're gonna say that, because
you're smart, you're obviously a brilliant doctor, and you'll find
something else to do if you cure cancer. So yeah,
that's that's okay with me. I think that's wonderful. Okay, Well,
I'll tell you what. It's been a fascinating conversation on
clinical Piles about trials with doctor jeddev Matt two, one
of the excellent doctors at OHC, and uh, do me
(10:28):
a favorite. Tell doctor Patel that Brian said, Hi, if
you run into Waterhouse, tell doctor Waterhouse Brian said, Hi too.
Those are wonderful, wonderful folks. So if you need a
second opinion, if you've got cancer and you're concerned about
the level of care you're getting, maybe you want to
want to look into one of these clinical trials. OHC
is doing them all the time. It's eight eight eight
six eight hundred eight eight eight sixty eight hundred online
(10:52):
ohcare dot com.
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