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November 25, 2025 8 mins
  • A widely used grease remover and dry-cleaning chemical called tetrachloroethylene (PCE) has been linked to liver fibrosis, a condition that causes scarring and loss of liver function even in people who don't drink alcohol or have obesity
  • Researchers found that people with measurable levels of PCE in their blood were three times more likely to have liver fibrosis, and for every tiny one-nanogram-per-milliliter increase in PCE, the risk increased fivefold
  • PCE exposure often occurs through inhaling fumes from dry-cleaned clothes, contaminated air, or drinking water, and the chemical can also enter through the skin, affecting the liver, kidneys, heart, and nervous system
  • Long-term exposure to PCE has been linked not only to liver disease but also to nerve damage, reproductive issues, and several cancers, including those of the bladder and liver, prompting the EPA to begin phasing it out
  • Lower your risk of liver damage by switching to solvent-free wet cleaning, letting dry-cleaned clothes air out before use, replacing household products that contain PCE, and supporting liver repair through clean nutrition, hydration, and sun exposure
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