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July 16, 2025 7 mins

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  • Motivation isn’t just about willpower; it also starts with brain chemistry. Dopamine drives your internal momentum to act, and thiamine plays a key role in keeping this system energized
  • Thiamine deficiency disrupts energy metabolism in high-demand organs like the brain and heart. Early symptoms include fatigue, brain fog, irritability, and poor physical recovery after exertion
  • New research shows a fat-soluble form of thiamine called tetrahydrofurfuryl disulfide (TTFD) increases your motivation to exercise by activating brain arousal systems
  • Thiamine also helps your body clear fatigue by improving lactate handling and carbon dioxide output, both of which are essential for efficient recovery after physical or mental exertion
  • To support healthy thiamine levels, eat nutrient-dense whole foods that provide a spectrum of B vitamins, avoid alcohol and refined sugar, supplement when needed, and correct magnesium deficiency
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