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November 22, 2025 7 mins
  • Skin cancer affects one in five Americans, with nonmelanoma types like basal and squamous cell carcinoma making up most cases. Niacinamide, a form of vitamin B3, is found to offer a strong preventive effect
  • A recent study published in JAMA Dermatology associated niacinamide use with a 14% lower overall risk of developing additional nonmelanoma skin cancers, with the greatest benefit seen after the first cancer diagnosis
  • Earlier research showed that taking 500 milligrams of niacinamide twice daily reduced new nonmelanoma skin cancers by 23% and precancerous lesions by up to 15%
  • Niacinamide protects your skin by restoring NAD+ for DNA repair, reducing inflammation, supporting immune defenses, and strengthening the barrier that maintains moisture and resilience against environmental stress
  • For long-term use, smaller daily doses of 50 milligrams three times per day are safe and sustainable. Combining niacinamide with sensible sun exposure habits and good nutrition strengthens skin defense naturally
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