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July 28, 2025 6 mins

Story at-a-glance

  • Linoleic acid (LA), once a trace nutrient in the human diet, now makes up as much as 25% of daily calories for many Americans, leading to mitochondrial dysfunction and long-term metabolic stress
  • LA transforms into harmful byproducts called OXLAMs that damage DNA, impair cellular energy production, and drive inflammation linked to heart disease, obesity, diabetes, and neurodegeneration
  • This polyunsaturated fat embeds in your body for years; it requires up to six years of low-LA eating to replace 95% of what’s already stored in your tissues
  • Common sources of LA include vegetable oils, processed foods, poultry, pork and even many products marketed as healthy, like organic nut butters and salad dressings
  • Reducing your LA intake by eliminating vegetable oils and switching to stable animal fats gives your mitochondria a chance to recover and helps lower your chronic disease risk over time
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