Best Friends with Nicole Byer and Sasheer Zamata

Best Friends with Nicole Byer and Sasheer Zamata

Gayle & Oprah. Bonnie & Clyde. Nicole & Sasheer. Enter the pantheon of best friendship. When you’re forced to change your number, are sick of being single, or want to take a pole-dancing class, you’re going to need a best friend...and if you don’t, you can still have this podcast. This is a Headgum podcast. Follow Headgum on Twitter, Instagram, and Tiktok. Advertise on Best Friends via Gumball.fm.

Episodes

October 29, 2025 65 mins

We have a very special guest this week - one of Nicole and Sasheer's best friends, actor and musician Tawny Newsome (Space Force, Star Trek: Lower Decks)! The trio gets into strength-training, the multitude of activities you can do outside with your friends, the joy of adult coloring books, and Tawny's memorable night on the town that solidified a best friendship.

Watch this full video on YouTube and follow below!

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Nicole and Sasheer are back from a quick trip to Vegas and ready to break down all of their funniest moments, from seeing Ashlee Simpson to their beloved Cirque Du Soleil. Nicole and Sasheer also recount their very different mornings - one involves the fire department (spoiler: everything's fine!) and the other involves stealing fruit. Tune in to find out what happened to who and why and how!

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This week, Nicole and Sasheer are joined by two very special guests and hosts of the podcast Sloppy Seconds, Big Dipper and Meatball! Our host duos discuss the ins and outs of working with your best friend, rumors regarding the cleanliness of restaurant ice, and play an exciting round of Besting Each Other.

Episode Quiz: https://www.buzzfeed.com/itztocaviolet/fruit-personality-quiz

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October 8, 2025 56 mins

Nicole and Sasheer finally take their first Buzzfeed quiz since the hiatus to figure out what fruit they are... but fair warning, it doesn’t go as expected. Also discussed are the many interpretations of the hugging emoji, going to the beach in New York, and ways to stay connected to friends while being in different life phases. 

Episode Quiz: https://www.buzzfeed.com/itztocaviolet/fruit-personality-quiz

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October 1, 2025 58 mins

We're back with another episode of Best Friends! Nicole and Sasheer get into the difference between their backyard experiences, examine and consider a multitude of maps, and debate the pros and cons of traveling to a remote island that doesn't welcome outsiders.

Watch this full video on YouTube and follow below!


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September 24, 2025 59 mins

This week, Nicole and Sasheer walk through Nicole's joyful experience at The Sizzler, learn all about BieberGate 2025, and consider the implications of a monthly lasagna party.


Watch this full video on YouTube and follow below!


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This week, Nicole and Sasheer are joined by special guest and friend, Harvey Guillén (What We Do In The Shadows, Puss in Boots: The Last Wish)! The trio share some early audition horror stories, consider friendship levels of closeness being like a gorgeous tiered cake, and the specific joy of watching the sweepers at a Dodger's game.

Watch this full video on YouTube and follow below!


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Nicole and Sasheer have a very special friend joining them today - comedian extraordinaire Margaret Cho! The trio gets into their preferences on all things haunted, pet psychics, receiving signs in the universe from friends that have passed on, and Nicole's ongoing quest to join Cirque du Soleil.


Watch this full video on YouTube and follow below!


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September 3, 2025 66 mins

Nicole and Sasheer have a very special friend joining them today - the wonderful Owen Thiele (Adults, Overcompensating, Theater Camp)! The trio gets into an exciting brand new segment called "Why Were You Late?", different confrontational strategies depending on if you are a) in or b) out of your car, and what it means to be a friend collector vs friend recycler.


Watch this full video on YouTube and follow below!


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August 27, 2025 62 mins

This week, Nicole and Sasheer go all the way back to the Old Testament to revisit some classic stories with a 2025 POV. They also get into Jubilee vs Jolibee, some flamingo pants Nicole is on the hunt for, and bidet etiquette.


Watch this full video on YouTube and follow below!


Follow Nicole: Twitter, Instagram, TikTok

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August 20, 2025 61 mins

We're back! Sasheer just returned from a gorgeous trip to Japan and is ready to fill us in on all of her fun travel stories. She also has a special souvenir for Nicole that (spoiler!) Nicole goes nuts for. Also discussed: the why? of wearing thongs, chicken breasts vs thighs, and the age old question of "Where's the beef?"


Watch this full video on YouTube and follow below!


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August 13, 2025 61 mins

Nicole and Sasheer waste no time this week debriefing what they're loving lately - labubus, food shaped candles, real tea (gossip) vs real tea (beverage), how a garden tomato is nature's ketchup, and their unintentionally perfectly compatible chocolate chip cookie preferences.


Watch this full video on YouTube and follow below!


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August 6, 2025 61 mins

Nicole and Sasheer are back with another episode of Best Friends and they're getting right into the big questions: Are feet scary hands? Why do people walk around hotel lobbies barefoot? Who is Albert Nobbs? All of this and more (answering Best Friends listener questions from the vault!) will be revealed.


Watch this full video on YouTube and follow below!


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Not only are Nicole and Sasheer best friends, they're also back to recording their podcast about being best friends, Best Friends! Join them as they catch up on all of the fun things that have been going on since their last recording, from debriefing films like Nosferatu and Jurassic Park to learning the truth about what dolphins are up to.


Watch this full video on YouTube and follow below!


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December 25, 2024 52 mins

Nicole and Sasheer are back and ready to discuss gel manicures, late-night projects, Nicole's merch, sewing club, farming, Nicole's sport mode crocks, softball, baseball, stadium dancers, rugby, the premise of Down To Earth, and WandaVision. Plus Nicole and Sasheer answer your questions about confrontation.  Email or call Nicole & Sasheer with your friendship questions at: nicoleandsasheer@gmail.com

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Recorded live at the Largo at the Coronet, Nicole and Sasheer swap weird interview questions they have been asked, try to find the actual Paul Blart, pitch easy acronyms, and celebrate Nicole’s small foot movements. They recap the highlights of their Hawaii trip, their mission to see the giant dildo, if either of them are approachable, and getting into fights at the airport. They take a quiz where they take a trip to Costc...

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3-2-1 - HAPPY SASHEER! HAPPY NICOLE! This week we discuss undressing shrimp, restaurant horror stories, post-covid bad behavior, why everyone is talking to Nicole at the airport, birth stones and their spiritual meanings, Nicole’s ceiling keyboard, the colors everyone wants to see on Sasheer, going braless, and more. They take a quiz to see if they would be better with Shrek or Prince Charming, and answer a listener questi...

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December 4, 2024 56 mins

Hello, mhmm! This week we talk about Sasheer’s overenthusiastic fan, break down TI’s antics/bad behavior at comedy shows, the things fans yell at Nicole, Sasheer’s busy travel schedule, Nicole’s private jet dreams, celeb sightings on planes, take another swing at the “I Hate” game, luxurious car washes, and more. They take a quiz to find their most toxic trait, and answer listener questions on whether you should push yours...

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OH WOW HELLO! This week Nicole and Sasheer cover Nicole’s travel mishaps and newest nemesis, what a manifesto really is, plane-snoring, airline etiquette, Nicole’s new friend Ed - the CEO of Delta, pilots who sleep at the wheel. Then, Nicole and Sasheer answer listener questions about how to feel okay about your ex/current friend moving on, and how to have hard conversations with roommates. Plus - roller crocs?!?  

 

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November 20, 2024 50 mins

S! H! Wait…  Nicole's having issues with spelling today! This week Nicole breaks down the beats in the movie Curly Sue, Sasheer shares about getting better at skating, Nicole gets a new indoor pole, Sasheer shares that she is a morning person, Nicole has weak snaps and cute sneezes, Sasheer teaches us what a housecoat is, Nicole opens up about her tambourine dreams, and more. They take a quiz to find out what their chronot...

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