Best Friends with Nicole Byer and Sasheer Zamata

Best Friends with Nicole Byer and Sasheer Zamata

Gayle & Oprah. Bonnie & Clyde. Nicole & Sasheer. Enter the pantheon of best friendship. When you’re forced to change your number, are sick of being single, or want to take a pole-dancing class, you’re going to need a best friend...and if you don’t, you can still have this podcast. This is a Headgum podcast. Follow Headgum on Twitter, Instagram, and Tiktok. Advertise on Best Friends via Gumball.fm.

Episodes

December 24, 2025 68 mins

Happy Holidays from Best Friends! This week, Nicole and Sasheer get into the latest Avatar film, how they react differently during emergencies, and take the wildest quiz yet in the history of Best Friends!

QUIZ: https://ela-ine.github.io/what-vehicle-are-you/index.html

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Nicole and Sasheer are excited to welcome very special guest, filmmaker Paul Feig (Bridesmaids, Freaks and Geeks, A Simple Favor, Spy) to chat about his upcoming film, The Housemaid, which is in theaters December 19th! Our trio of friends discusses what makes a friendship movie great, a shared past passion for tap dance, and the best piece of test audience feedback Paul ever received.

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December 10, 2025 59 mins

Nicole and Sasheer are back for an extra special solo episode of Best Friends! Nicole gives the update on her latest apple discoveries and considers the best way to get backstage at Beyoncé. Sasheer gives a fantastic enactment of sitting in an exit row and important advice to a listener that involves sprinting towards a group of people. Get into it!

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December 3, 2025 60 mins

Nicole and Sasheer are back from a night out on the town to catch up with each other about kissing in the rain, the joy of lasagna, butt facials, neutering and Nicole's giraffe family.

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November 19, 2025 63 mins

Nicole and Sasheer are back with a special solo episode for your video watching eyes and podcast listening ears! They get into Nicole's latest musical fixation, Sasheer's cat's recent escape attempt, take a quiz and answer some questions from the lovely listeners.

Quiz Link: https://www.proprofs.com/quiz-school/story.php?title=pq-what-type-of-vehicle-are-you

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This week, Nicole and Sasheer are joined by best friends Betsy Sodaro (A Funny Feeling, We Love Trash) and Gilli Nissim (The Other Two, Twisted Metal, AP Bio)! The group gets into the story behind Betsy and Gilli's matching shirts, memories from their trip to Bulgaria where Betsy filmed a commercial playing an eye mite, and the absolute joy of living with a best friend!

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November 5, 2025 62 mins

Nicole and Sasheer are back in the studio to debrief Sasheer’s house project, uncover the origin story of cereal mascots, try a new quiz and answer some friendship advice questions from our gorgeous listeners.

QUIZ: https://www.autostraddle.com/quiz-which-classic-bath-and-body-works-scent-are-you/?results=44c723e2

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We have a very special guest this week - one of Nicole and Sasheer's best friends, actor and musician Tawny Newsome (Space Force, Star Trek: Lower Decks)! The trio gets into strength-training, the multitude of activities you can do outside with your friends, the joy of adult coloring books, and Tawny's memorable night on the town that solidified a best friendship.

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October 22, 2025 61 mins

Nicole and Sasheer are back from a quick trip to Vegas and ready to break down all of their funniest moments, from seeing Ashlee Simpson to their beloved Cirque Du Soleil. Nicole and Sasheer also recount their very different mornings - one involves the fire department (spoiler: everything's fine!) and the other involves stealing fruit. Tune in to find out what happened to who and why and how!

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This week, Nicole and Sasheer are joined by two very special guests and hosts of the podcast Sloppy Seconds, Big Dipper and Meatball! Our host duos discuss the ins and outs of working with your best friend, rumors regarding the cleanliness of restaurant ice, and play an exciting round of Besting Each Other.

Episode Quiz: https://www.buzzfeed.com/itztocaviolet/fruit-personality-quiz

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October 8, 2025 56 mins

Nicole and Sasheer finally take their first Buzzfeed quiz since the hiatus to figure out what fruit they are... but fair warning, it doesn’t go as expected. Also discussed are the many interpretations of the hugging emoji, going to the beach in New York, and ways to stay connected to friends while being in different life phases. 

Episode Quiz: https://www.buzzfeed.com/itztocaviolet/fruit-personality-quiz

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October 1, 2025 58 mins

We're back with another episode of Best Friends! Nicole and Sasheer get into the difference between their backyard experiences, examine and consider a multitude of maps, and debate the pros and cons of traveling to a remote island that doesn't welcome outsiders.

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September 24, 2025 59 mins

This week, Nicole and Sasheer walk through Nicole's joyful experience at The Sizzler, learn all about BieberGate 2025, and consider the implications of a monthly lasagna party.


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This week, Nicole and Sasheer are joined by special guest and friend, Harvey Guillén (What We Do In The Shadows, Puss in Boots: The Last Wish)! The trio share some early audition horror stories, consider friendship levels of closeness being like a gorgeous tiered cake, and the specific joy of watching the sweepers at a Dodger's game.

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Nicole and Sasheer have a very special friend joining them today - comedian extraordinaire Margaret Cho! The trio gets into their preferences on all things haunted, pet psychics, receiving signs in the universe from friends that have passed on, and Nicole's ongoing quest to join Cirque du Soleil.


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September 3, 2025 66 mins

Nicole and Sasheer have a very special friend joining them today - the wonderful Owen Thiele (Adults, Overcompensating, Theater Camp)! The trio gets into an exciting brand new segment called "Why Were You Late?", different confrontational strategies depending on if you are a) in or b) out of your car, and what it means to be a friend collector vs friend recycler.


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August 27, 2025 62 mins

This week, Nicole and Sasheer go all the way back to the Old Testament to revisit some classic stories with a 2025 POV. They also get into Jubilee vs Jolibee, some flamingo pants Nicole is on the hunt for, and bidet etiquette.


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August 20, 2025 61 mins

We're back! Sasheer just returned from a gorgeous trip to Japan and is ready to fill us in on all of her fun travel stories. She also has a special souvenir for Nicole that (spoiler!) Nicole goes nuts for. Also discussed: the why? of wearing thongs, chicken breasts vs thighs, and the age old question of "Where's the beef?"


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August 13, 2025 61 mins

Nicole and Sasheer waste no time this week debriefing what they're loving lately - labubus, food shaped candles, real tea (gossip) vs real tea (beverage), how a garden tomato is nature's ketchup, and their unintentionally perfectly compatible chocolate chip cookie preferences.


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August 6, 2025 61 mins

Nicole and Sasheer are back with another episode of Best Friends and they're getting right into the big questions: Are feet scary hands? Why do people walk around hotel lobbies barefoot? Who is Albert Nobbs? All of this and more (answering Best Friends listener questions from the vault!) will be revealed.


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