Dr. Derrick DeSilva explores how the gut microbiome influences aging by shaping immune function, digestion, vitamin production and neurotransmitter levels. He reviews research showing centenarians harbor unique bacteria that produce protective secondary bile acids and discusses how those compounds can slow harmful infections.
The episode highlights the role of butyrate-producing bacteria (e.g., Faecalibacterium prausnitzii) in reducing inflammation, supporting mitochondrial function, protecting telomeres and promoting cellular cleanup, all linked to healthier aging.
Practical takeaways include using effective probiotics, optimizing nutrients (vitamin D, A, K, methylated B complex), considering genetics and lifestyle changes.
Popular Podcasts
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
The Joe Rogan Experience
The official podcast of comedian Joe Rogan.
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.