All Episodes

May 8, 2025 3 mins
Do Genetics Determine My Response to Metformin?

This episode is proudly sponsored by PlexusDx - your trusted partner in precision health. Discover the power of personalized wellness with our Glucose, Insulin, and GLP-1 Genetic Test and over 25 cutting-edge health and wellness genetic tests designed to help you optimize your health. Visit PlexusDx.com to learn more. Now, let’s dive into today’s episode!

Welcome to our educational podcast episode where we explore an important question: Do genetics determine my response to metformin? This topic has been on the minds of many, especially those managing type 2 diabetes.

When it comes to medications like metformin, which is commonly prescribed for managing type 2 diabetes, not everyone reacts the same way. Some individuals find it works wonders, while others may experience side effects or even find it ineffective. A significant part of this variability can be traced back to our genetics.

Specific genes play a crucial role in how our bodies process metformin. For instance, the SLCO1B1 gene is key in determining how well metformin is absorbed and metabolized. Additionally, the ABCB1 gene is involved in drug transport across our cells. Variations in these genes can lead to different outcomes regarding blood sugar control.

Another important gene to consider is the MTHFR gene. While primarily known for its role in folate metabolism, variations in this gene can also influence how we respond to medications like metformin. This is where genetic testing can be incredibly beneficial. By understanding your genetic makeup, you can gain insights that help you and your healthcare provider tailor your treatment plan more effectively.

So, why does this matter? Personalized health insights are becoming increasingly important in modern medicine. With genetic testing becoming more accessible, you can learn about your unique genetic profile and how it might affect your health. This knowledge empowers you to work with your healthcare provider to optimize your treatment plan, potentially adjusting dosages or exploring alternative options if needed.

Here are a few practical steps you can take with this information:

  • Always consult with your healthcare provider before making any changes to your medication. They can help you interpret your genetic test results and guide you in making informed decisions.
  • Consider getting genetic testing. Tests like the MTHFR genetic test can provide valuable insights into how your genetics might influence your response to metformin.
  • Keep track of how you feel while on metformin. Note any side effects or changes in your blood sugar levels. This information is helpful for your healthcare provider when discussing your treatment.
  • Stay informed! Understanding how genetic factors influence medication effectiveness can help you manage your health better.

If you’re interested in exploring your genetic makeup further, we highly recommend checking out the innovative precision health and wellness genetic tests available from PlexusDx. They offer a range of saliva-based tests that cover everything from nutrition to overall health risk management. You can find these tests at PlexusDx.com, Amazon, and Walmart.com.

Remember, understanding your genetics is a significant step toward better health. If you found this post insightful, please like and subscribe for more information!

Thank you for reading, and don’t forget to check out the links to PlexusDx tests for more information on how you can take charge of your health through genetic insights.

Disclaimer: PlexusDx is a personalized health report and laboratory testing service, which enables users to obtain science-based, evidence-backed health and wellness information based on their genome. Always consult a licensed healthcare provider for concerns about your health and before you stop or start any medical treatment.

Where to Buy PlexusDx Genetic Tests

Ready to take control of your health with precision genetic insights? You can purchase the PlexusDx Glucose, Insulin and GLP-1 Genetic Test from these trusted retailers:

  • 👉 PlexusDx – Order directly from our official website.
  • 👉 Amazon – Convenient shopping with fast shipping.
  • 👉 Walmart – Buy online from a trusted retailer.

Get your personalized DNA insights tod

Mark as Played

Advertise With Us

Popular Podcasts

Las Culturistas with Matt Rogers and Bowen Yang

Las Culturistas with Matt Rogers and Bowen Yang

Ding dong! Join your culture consultants, Matt Rogers and Bowen Yang, on an unforgettable journey into the beating heart of CULTURE. Alongside sizzling special guests, they GET INTO the hottest pop-culture moments of the day and the formative cultural experiences that turned them into Culturistas. Produced by the Big Money Players Network and iHeartRadio.

Crime Junkie

Crime Junkie

Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.

Stuff You Should Know

Stuff You Should Know

If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.