Creating Memory: Vaccines & Immunity

We talk with Dr. Bernadeta Dadonaite, a research associate  at the Fred Hutchinson Cancer Center, WA, who studies interactions between the influenza attachment protein hemagglutinin and its newly identified receptor protein, MHC-II.

We talk with Dr. Julianna Han, a senior staff scientist at the Scripps Research institute, CA, who studies antibody-epitope interactions following human influenza virus infection and vaccination to inform the development of novel influenza immunogens and antibody therapeutics. 

We talk with Dr. Daniel Malouli, an assistant professor at the Vaccine and Gene Therapy Institute at the Oregon Health and Science University, OR, who studies how virus-host interactions modulate CMV infection and pathogenesis as well as determine the safety and efficacy of CMV-based vaccine vectors.  

We talk with Dr. Sumanta Naik, a staff scientist in the Department of Molecular Microbiology at Washington University School of Medicine, who is investigating the role of IRGM1 in type I interferon and B cell responses following vaccination and tuberculosis infection. 

We talk with Dr. Mario Feldman, Professor of Microbiology at Washington University School of Medicine in St. Louis, MO who studies the pathogenesis of Acinetobacter and the biogenesis of bacterial extracellular vesicles.

We talk with Dr. Daniel Hoft, Director of the Division of Infectious Diseases, Allergy & Immunology and the Center for Vaccine Development at Saint Louis University School of Medicine in St. Louis, MO who studies the development of T-cell targeting vaccines against mucosally-invasive intracellular pathogens such as tuberculosis and influenza.

We talk with Dr. Michela Locci, Associate Professor of Microbiology at the University of Pennsylvania Perelman School of Medicine in Philadelphia, PA who studies how T follicular helper cells promote optimal germinal cell reactions and antibody responses following vaccination.

We talk with Dr. Namit Chaudhary, a postdoctoral researcher in the Department of Immunology & Microbiology at The Scripps Research Institute, CA, who develops new technologies to generate a safe and effective single-shot lipid nanoparticle-based HIV vaccine. 

We talk with Dr. Zhouming Liu, an assistant professor of Molecular Microbiology at Washington University School of Medicine, MO, who studies mechanisms of La Cross virus entry and monoclonal antibody–mediated inhibition of infection.

We talk with Dr. Annie Elong Ngono, a research instructor in the Center for Vaccine Innovation at the La Jolla Institute for Immunology, CA, who studies the role of T cells in vaccine-mediated protection and neurological disease following flavivirus infection.

We talk with Dr. Anass Abbad, a postdoctoral fellow in the Department of Microbiology at the Icahn School of Medicine Mount Sinai, NY who studies humoral immune responses and virus-host receptor interactions to design next generation pandemic virus vaccines.

We talk with Dr. Sandhya Bangaru, a staff scientist in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute, CA who uses advances in cryo-EM to understand antibody epitopes important for their antiviral protective activity and their pathogenic activity in allergic diseases.

We talk with Dr. Florian Krammer, the endowed Mount Sinai Professor of Vaccinology at the Icahn School of Medicine, New York, NY and Director of the Ludwig Boltzmann Institute for Science Communication and Pandemic Preparedness at the Medical University of Vienna, Austria, who studies the B cell response in the context of natural infection to better understand how to design broadly protective and durable vaccines.

We talk with Dr. John Gridley, a postdoctoral fellow in the Vaccinology Training Program at Emory University, GA, who uses a hepatitis C virus-related rodent hepacivirus model to identify correlates of protective immunity for HCV and the role of inducible Hepatic-Associated Lymphoid Tissue (iHALT) in the induction of this immune response.

We talk with Dr. Sandro Galea, Dean and Professor of the School of Public Health at Washington University in St. Louis, who uses population based sciences to promote health locally and globally.

We talk with Dr. Hedda Wardemann, Division Head of B Cell Immunology at the German Cancer Research Center and Professor at the Medical Faculty of the University of Heidelberg in Heidelberg, Germany, who studies B cell responses in the context of infectious disease and cancer.

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We talk with Dr. Emanuele Andreano, Head of Serology and Immunology at Fondazione Biotecnopolo di Siena, Italy, who combines immunology, structural biology and artificial intelligence to rapidly develop novel monoclonal antibodies therapies and antiviral vaccine targets.

We talk with Dr. Daniel Wrapp, Assistant Professor Assistant Professor at the Duke Human Vaccine Institute at Duke University School of Medicine, NC, who uses structure-based design to develop novel therapeutic interventions against viruses.

We talk with Dr. Paeton Wantuch, a Staff Scientist in the Department of Pediatrics at Washington University School of Medicine, MO, who uses animal models to understand correlates of protection for vaccines against Klebsiella pneumoniae.