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November 21, 2024 19 mins

In this episode of Curing with Sound, three leading experts in focused ultrasound technology share their groundbreaking work in pancreatic cancer treatment. Dr. Feng Wu from Oxford University, Dr. Jae Young Lee from Seoul National University Hospital, and Dr. Joan Vidal-Jové from Barcelona's Comprehensive Tumor Center discuss their innovative approaches to treating one of medicine's most challenging cancers using noninvasive focused ultrasound techniques. The episode provides insights into the evolution and future of focused ultrasound technology in cancer treatment. The experts detail how their work addresses key challenges in pancreatic cancer treatment, from enhancing drug delivery to activating immune responses. Key Points:

  • Focused ultrasound technology shows particular promise in addressing the unique challenges of pancreatic cancer, including the ability to precisely target tumors while preserving surrounding critical structures.
  • Multiple treatment pathways are being explored simultaneously: thermal ablation (HIFU), mechanical stimulation for drug delivery enhancement, and histotripsy for immune system activation, offering new hope for patients with limited treatment options.
  • Dr. Lee shares exciting results from his phase II clinical trial combining focused ultrasound with chemotherapy, achieving a 63% objective response rate.
  • Dr. Wu discusses combining HIFU ablation with drug delivery to overcome limitations in treating pancreatic cancer.
  • Dr. Vidal-Jové reveals how histotripsy treatment has shown remarkable immune system activation effects. 

SHOW TRANSCRIPT ---------------------------- QUESTIONS? Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances. 

Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation. 

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