Deep Dive In Vitiligo

She built an empire on perfection — but when Martha Stewart casually revealed she’s had vitiligo for decades, it wasn’t a headline grab. It was something better: real.

In Episode 32 of Deep Dive in Vitiligo, we unpack why Martha’s low-key confession matters. From Michael Jackson’s media storm to Winnie Harlow’s modeling revolution, to Jon Hamm and Joe Rogan’s quiet acknowledgments — every story chips awa...

This time, we’re zooming out — way out — to look at vitiligo not just as a skin condition, but as a surprising window into your overall health. From heart disease and immune superpowers to the role stress plays in flipping genetic switches, this one’s a journey through the body (and maybe even time).

We break down a fascinating new study that links vitiligo to a slightly higher risk of coronary heart disease — but hold that panic b...

Can a handful of supplements really make a difference in managing vitiligo? In this episode, we sift through the science and separate fact from fantasy when it comes to vitamins and herbal remedies commonly linked to vitiligo care.

From the antioxidant power of Vitamin C to the immune-modulating promise of high-dose Vitamin D, Ginkgo Biloba, and Polypodium leucotomos, we explore what the research actually says—and what it doesn’t. ...

Vitiligo is known for its impact on skin—but what if it also changes the way you hear the world?

In this episode, we explore the surprising link between vitiligo and high-frequency hearing loss, drawing on recent research and insights from the Vitiligo Research Foundation.

You’ll learn how melanocytes—cells that give skin its color—also play a key role in the inner ear, and how their loss m...

This week, we explore why common hair removal methods—like waxing, shaving, laser, and chemical depilatories—can pose unexpected risks for people with vitiligo. From the Koebner phenomenon (when skin trauma triggers new depigmented patches) to sensitivity issues and slowed healing, we unpack what you need to know before your next grooming routine.

What’s safest? What’s potentially harmful? And what role ...

In this powerful episode, we trace the extraordinary rise of World Vitiligo Day (WVD)—from scattered local efforts to a globally recognized health campaign that’s transforming lives.

We begin by going beyond the surface, uncovering the true nature of vitiligo as a serious autoimmune disease with deep psychological and social consequences, especially in underserved regions of Asia and Africa. Through personal stories and expert insi...

Do large language models like ChatGPT or Deep Seek actually understand the world, or are they just really good at faking it?

In this episode, we dig into the debate: are LLMs building genuine “world models” or just recycling patterns from massive datasets? We’ll explore real-world AI fails, like the skin lesion detector that linked rulers to cancer, and what that means for AI in diagnosing conditions like vitiligo.

Tune in to get t...

Today, we’re diving into the cutting-edge world of vitiligo research. We’re talking about the latest clinical trials, game-changing treatments like Opzelura and JAK inhibitors, and why getting involved in these trials isn’t just about early access—it’s about making a real impact.

Thinking about joining a trial? We’ll cover what you need to know—eligibility, what to expect, and why talking to your doctor is key.

Suggested reading: 

In this episode, we uncover the forgotten history of the National Vitiligo Control Act—a bold bill from the 1970s aimed at transforming lives affected by vitiligo. Thought lost to time, it was rediscovered in 2015 by Yan Valle, CEO of the Vitiligo Research Foundation, reigniting hope and advocacy.

Join us as we explore: 🎙️ The origins of the Act and its champion, Congressman Parren J. Mitchell, who battled vitiligo himself. 🎙️ Th...

Vitiligo is more than a skin condition—it affects identity, confidence, and emotional well-being. The stress and anxiety linked to vitiligo can disrupt sleep, creating a cycle of restlessness and fatigue. High cortisol levels from stress interfere with the sleep-wake cycle, while autoimmune inflammation and emotional distress worsen insomnia.

But what if breaking that vicious cycle could improve both mental health and skin healing?

Two new studies reveal the promise and challenges of using AI-chatbots in healthcare.  

In one study, ChatGPT outperformed doctors in diagnosing illnesses from case histories, with a 90% accuracy rate compared to doctors' 76%. However, it also showed that many doctors stick to their own judgment and don’t fully utilize AI’s potential.  

Another study focused on pharmacy settings found ChatGPT struggled with complex medical question...

In this inspiring episode, we dive into More Than Our Skin, the award-winning documentary that’s changing how the world sees vitiligo. Through the powerful stories of five remarkable women, we explore resilience, self-acceptance, and the beauty of embracing our differences. Along the way, we’ll discuss the latest in vitiligo advocacy, medical breakthroughs, and the ripple effect this film is creating in the world.

Read more: Beneat...

Could vitiligo hold the key to a longer, healthier life? Groundbreaking research from Korea reveals that individuals with vitiligo have lower risks of major diseases like cancer, heart issues, and infections.

In this episode, we explore the science behind these findings, from immune "white armor" to enhanced cellular cleanup.

Join us as we challenge the narrative and uncover the hidden strengths of this misunderstood condition. Sta...

Starting a vitiligo support group is a meaningful way to connect people, share experiences, and build a strong sense of community. In 2025, the focus should shift to creating local groups rather than relying on a centralized network.

Centralized systems, like a single online group, risk power imbalances, where decision-making is concentrated among a few.

This is similar to the pitfalls of centralized digital currencies controlled b...

In the 17th episode of Deep Dive in Vitiligo, we wrap up the year with a thoughtful analysis of the vitiligo drug development landscape, exploring the breakthroughs, challenges, and opportunities shaping the future of care. From pharmaceutical giants to AI-driven startups, we delve into the science, strategies, and collaborations pushing the boundaries of what’s possible.

The Titans of Treatment 

Leading the charge is Incyte with O...

In this podcast episode Mind, Body, and Ayahuasca: An Uncharted Approach to Vitiligo, we venture into the intersection of ancient Amazonian medicine and modern science to explore innovative avenues for vitiligo treatment.

Vitiligo, an autoimmune condition leading to skin depigmentation, presents both physical and psychological challenges. Traditional treatments often focus solely on the physical aspects, potentially overlooking the...

In this episode, we uncover the strategies and innovations behind recent pharmaceutical breakthroughs. Despite intense competition and the shifting landscape of Medicare Part D, Incyte continues to lead with strategic maneuvers and a patient-centered approach. We’ll delve deeper into Opzelura, an FDA-approved treatment for AD and vitiligo, shedding light on the financial and emotional burdens of these conditions and the high stakes...

How does pregnancy affect vitiligo, and can vitiligo influence pregnancy outcomes? This episode unpacks the intricate relationship between the two, exploring research on how hormonal changes—particularly cortisol and IL-10—can stabilize or worsen vitiligo symptoms.

We also address concerns about potential pregnancy risks, including an increased likelihood of complications, while highlighting preconception treatments that could help...