The Truth About GLP-1s and Midlife Weight Loss

GLP-1s like semaglutide are everywhere—from Oprah’s special to TikTok trends—but what’s the real story behind the shot? Lisa opens up about her personal experience with compounded semaglutide, sharing the good, the gross, and the emotionally complicated parts of using a GLP-1 medication in midlife.

Karen and Lisa dig into the cultural shame around weight, the privilege baked into access, and why it’s time we stop calling it “cheating” when women use tools to reclaim their health. From food noise to dosage mishaps (yep, she overdosed herself), this is the unfiltered conversation about semaglutide that the internet needs—and midlife women deserve.

In this episode:

• GLP-1s and how they actually work

• Lisa’s path from resistance to results

• The truth about side effects and blood sugar

• Why shame has no place in women’s health

• Access, equity, and the pharmacy black market

This one’s for anyone who’s ever looked in the mirror and thought, Wait… who even is this?

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🍸☕What We Were Drinking:

Popwell Prebiotic Soda #popwell

Mortal Kombucha #mortalkombucha

🎧Show Notes

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Connect with your hosts: ✨ Karen Shatafian – www.karenshatafian.com ✨ Lisa Corricello-McDowell – www.nextlevellifewithlisa.com