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May 2, 2025 8 mins

 

Summary: Low-carb, high-fat diets may deliver short-term results, but prolonged suppression of glucose metabolism can lead to mitochondrial dysfunction, reduced thyroid function, and chronic fatigue. In this episode, we explore the mechanisms behind this metabolic shift, the role of linoleic acid in energy production, and practical steps to maintain balance for long-term health.

Disclaimer

This podcast is for informational purposes only and does not substitute professional medical advice. Individuals considering dietary changes should consult with a qualified healthcare provider to assess their individual needs and metabolic health.

Scientific References & Further Reading
  • Cell Metabolism – Impaired Glucose Metabolism and Thyroid Dysfunction in Low-Carb Diets

  • Journal of Clinical Endocrinology – Role of Thyroid Hormones in Energy Production

  • American Journal of Physiology – Effects of Linoleic Acid on Mitochondrial Function

  • International Journal of Molecular Sciences – Mitochondrial Dysfunction and Oxidative Stress

  • Journal of Nutritional Biochemistry – Metabolic Flexibility and Energy Production in Mitochondria

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