This Episode provides a review of the therapeutic potential of thiamine (vitamin B1) and its synthetic derivative, benfothiamine. Thiamine is an essential nutrient crucial for energy metabolism and the proper functioning of the nervous system, heart, and muscles. Thiamine deficiency can lead to various disorders, including neurological conditions. Benfothiamine, a more bioavailable and lipophilic thiamine precursor, has shown promise in treating conditions associated with thiamine deficiency, particularly diabetic complications, neurodegenerative diseases, an d inflammatory conditions, often demonstrating superior efficacy compared to thiamine
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