Most people scan their cholesterol panel and zero in on the LDL. But could there be a better indicator of risk hiding in plain sight?
In this episode, Dr. Regina Druz walks through the standard lipid panel (total cholesterol, LDL, HDL, and triglycerides) and explains why the context behind the numbers matters more than the numbers alone. She breaks down what each marker can and can’t tell you, why fasting makes a difference, and how calculated values like LDL can be misleading if the test wasn’t done correctly.
Dr. Druz also challenges the outdated idea of “good” and “bad” cholesterol and introduces a smarter way to think about risk: by focusing on the full picture, including ApoB and a simple ratio anyone can calculate with basic labs. That ratio? Triglycerides divided by HDL. It’s one of the clearest signals of insulin resistance, and one of the most overlooked.
Using a real patient example, Dr. Druz shows how to interpret results in context and why statins may not always be the answer. Could your elevated cholesterol actually be a sign of metabolic dysfunction? And if so, what would it take to reverse it?
As part two of the Statin Overprescribing Solution series, this episode offers a practical way to rethink your lipid profile, and a clear path toward better heart health!
Episode Breakdown:
00:00 Understanding the Lipid Profile
04:08 Cholesterol: Good, Bad, and Ugly
09:39 Importance of Fasting for Lipid Profile
14:05 Non-HDL Cholesterol and ApoB
21:21 Risk Categories: Low, Moderate, High, Very High, Extreme
32:00 Example Patient Case Study
40:09 Triglyceride to HDL Cholesterol Ratio
43:01 Insulin Resistance Indicator
46:03 Cardiometabolic Intervention
Links
ASCVD Risk Estimator: https://tools.acc.org/ascvd-risk-estimator-plus/#!/calculate/estimate/
Reynolds Risk Score: https://www.mdcalc.com/calc/3932/reynolds-risk-score-cardiovascular-risk-women
Schedule a Discovery Call: https://go.holisticheartcenters.com/apply
Access Courses and Events: https://holisticheartcenters.info/hearthealth
Get Heartwell Toolkits: https://shop.holisticheartcenters.com/
Schedule a Business Meeting:https://calendly.com/heartcenters
Connect with Dr. Regina Druz:
Website: http://holisticheartcenters.com
YouTube: https://www.youtube.com/@reginadruzmd
Instagram: https://www.instagram.com/dr.reginadruz
Facebook: https://www.facebook.com/holisticheartcenters
Twitter: https://x.com/heartCenters
TikTok: https://www.tiktok.com/@holisticheartcenters
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
Crime Junkie
Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.
Ridiculous History
History is beautiful, brutal and, often, ridiculous. Join Ben Bowlin and Noel Brown as they dive into some of the weirdest stories from across the span of human civilization in Ridiculous History, a podcast by iHeartRadio.