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December 21, 2025 7 mins

Deaths of despair and the opioid crisis: how suicide, overdose, and alcohol-related deaths were rising long before opioids took center stage. A data-driven look at opioid epidemic origins, mental health and religion, and how declining church attendance and community ties shaped overdose and suicide trends among middle aged white Americans. Understand the deeper roots of deaths of despair so you can recognize risk factors, rethink common narratives, and take practical steps in your own life and community.

What You'll Learn:

  • Why deaths of despair were rising well before the modern opioid crisis and what that reveals about suicide and overdose trends.
  • How declining church attendance and religious involvement may be linked to higher rates of overdose, suicide, and alcohol-related deaths.
  • What new research shows about middle aged white Americans, especially those with less education, and their vulnerability to deaths of despair.
  • How community decline, isolation, and loss of social institutions can interact with addiction and mental health struggles.
  • Why focusing only on the opioid supply misses the deeper social and psychological roots of the opioid epidemic origins.
  • How to spot early warning signs of deaths of despair in your own circles and start conversations grounded in empathy, not stigma.
  • Practical ways to strengthen community, connection, and support as a buffer against suicide, overdose, and alcohol-related harms.
  • Simple reflection and action steps you can take this week to apply what you’ve learned to your life, family, or local community.
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