Episode Transcript
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So in this respect, IGF one is actually pretty essential for healing.
.6666666667So just day-to-day healing.
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It's important for also building your muscle, especially if you're doing a lot of strength training and things like that.
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We want more IGF one or we want an adequate amount of IGF one in order to encourage more muscles to be built.
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But IGF one can also stimulate the growth of unwanted cells or damaged cells or pre-cancer or cancerous cells, and we want to make sure that we're not having too high of an IGF one level in the blood to encourage excessive growth of a lot of these precancer cancerous cells.
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basically IGF one can act like a fuel source where more IGF one can mean more growth signals for these cancer cells.
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So there's a bit of like a Goldilocks effect here.
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We want just enough to encourage some healthy processes to go on the body, but we don't want too much.
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That's going to encourage a lot of pro cancer growth going on in the body.
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Alright, so today we are going to be diving into a lab marker that I find often flies under the radar.
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We are specifically gonna be talking about IGF one insulin like growth factor one, which has a role to play in cancer growth and recurrence prevention.
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And you might already have gathered this by now, but I am a huge nerd when it comes to numbers and data points and understanding more about what is going on for the person in front of me.
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Alongside the general population evidence, but I really wanna get into the nitty gritty of people in front of us and what is, what is going on within their body.
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And I find that blood work is one of these things, uh, that we really overlook in terms of health and as well as cancer prevention because we can't just, we can't just ignore all the different factors on A CBC, for example, when we can look at all the different types of white blood cells and look at the ratios.
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And that gives us more information as a, as to the strength.
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Often whenever we, someone looks at a CBC panel, like a white blood cell count, they're just looking at the total white blood cell counts and they're saying, is that high? Is it low? But we can also look a little bit further and it's pretty much always included when we see at the, we see the level of all the different types of white blood cells that are there and just looking at those can give us even more information.
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Also, blood workers helps us to get a little bit more I dunno gets, it allows us to get at things faster so we can either rule things in or rule things out if we do a more full panel.
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We can look at everything from your vitamins, minerals, things like that, and quickly see are you tired because your iron's low? Is it B12 or is there something else that might be a little bit harder to identify going on? So it's just a quick rule in rule out.
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Our numbers can tell us that very easily on blood work.
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It gives us a little bit more information on like what's going on internally.
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Anyway, I won't go too much into that.
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Like I'm a huge nerd when it comes to blood work.
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All of our coaches are huge nerds now that we've, we've taught them in all of our processes and how to interpret and analyze blood work.
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We all love numbers and data points, and we can't get enough of it.
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And the other part of it is that it's often kind of cheap to get these done.
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I know in the big schema things these are in these costs can add up in terms of the total healthcare burden.
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But from an individualized level, like to get a vitamin D done is like 20, 25 bucks sometimes to kinda get that done.
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Whereas we know some other functional tests can be in the hundreds of dollars.
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So just getting some good comprehensive blood work can be very helpful.
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And in particular, looking at insulin growth factor one, which again is often overlooked even in functional medicine, gave us a little bit in of insight into maybe some potential growth factors when it comes to encouraging cancer to grow.
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So basically what is insulin growth factor one? It is kind of exactly what it sounds like.
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It is a growth promoting hormone that acts a lot like insulin and it's growth promoting in the way that it can be both good and bad.
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bad if it comes to cancer, but good in other ways.
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And I'll go into that in just a minute, but I just wanna let you know that this episode is gonna be helpful for you if you're wondering what or why blood sugar balance is important when it comes to cancer prevention, re recurrence prevention.
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If you've never had your IGF one, or maybe you've never even heard of it done, you've never had it tested before, and you're wondering like, is this something that you should really look into for yourself? And you wanna know kind of what is it? How does it pertain to you? And if you want to look at coming at a cancer recurrence prevention plan from a place of evidence and.
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Numbers as opposed to just kind of guesswork and throwing spaghetti at the wall.
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This is one part that you can add to your plan in order to give you that data point to say like, yes, I need to focus here.
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Well, I can definitely see this is a problem or not a problem in my body, and let's go at this and see what we can do to fix it.
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So let's go into this even more.
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Let's start with what is IGF one in a little bit more comprehensive, uh, points here.
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So, IGF one, it is a hormone produced by the liver.
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It is stimulated by another type of growth hormone, hormone, just kind of just called growth hormone, and basically IGF one, it helps cells to grow, to divide and make new healthy cells sometimes, and also to repair.
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So if there's any just low level damage that are going on with in cells, which happens to us every day, the the IGF one will go and help to repair those cells so that they become nice and healthy and full functioning again.
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So in this respect, IGF one is actually pretty essential for healing.
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So just day, day-to-day healing.
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it's important for also building your muscle, especially if you're doing a lot of strength training and things like that.
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We want more IGF one, or we want an adequate amount of IGF one in order to encourage more muscles to be built, built.
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Also it's, uh, good in terms of development.
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So everything from whenever you're just first being developed in the womb to potentially less encouraging your liver cells and is a part of brain function and things like that.
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So, IGF one has a lot of positive roles to play in the overall health of your body.
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IGF one can also stimulate the growth of on what cells or damaged cells or precancer or cancerous cells.
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And we want to make sure that we're not having too high of an IGF one level in the blood to encourage excessive growth of a lot of these precancer cancerous cells.
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IGF one can act like a fuel source where more IGF one can mean more growth signals for these cancer cells.
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So there's a bit of like a Goldilocks effect here.
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We want just enough to encourage some healthy processes to go on the body, but we don't want too much.
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That's going to encourage a lot of pro cancer cancer growth going on in the body.
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It's, it's complicated.
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IGF one.
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This relationship with the body is complicated.
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So why does it matter for cancer? You might have already put that together a little bit, but cancer is at its core, uncontrolled cell growth.
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It is when our normal cells have gotten multiple hits to them, which have turned them kind of muteness.
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there's a lot of mutations in there, and they have gone rogue and then the cells are unable to be repaired.
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There's, they're evading the immune system.
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And then if we're gonna throw IGF one into it, it's like gasoline on the fire where it's gonna encourage these cells to grow and grow and grow.
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So, high levels of IGF one.
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Human research have been shown to be associated with increased risks for several types of cancer.
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In particular, um, breast, prostate, colorectal cancers, as well as a couple others as well.
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But these are like the main ones that have been researched the other side.
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So not only can IGF one encourage the uncontrolled cell growth of these cancer cells, it can also prevent apoptosis, which is the definition, like the definition of it, is programmed cell death.
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Which means that it's gonna allow some damaged or abnormal cells to survive and multiply when our natural body's mechanisms, our protective mechanism should have been that that cell should have died off and been removed from the body and then replaced with another healthy cell.
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So instead of this damaged, like to call them mutinous.
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They have mutations, but they're also like, they're going against the grain.
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They're, they're being bad.
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These cells that are abnormal, they are being prevented from dying, and a lot of that can be due to high IGF one levels, like it's only one factor.
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There's a lot of different factors going on, but it is an important factor that potentially we can even make a difference with when it comes to nutrition lifestyle choices, which we'll get into in just a few minutes here before we get into like how do we manage IGF one? Let's figure out first if it is even something that you need to manage.
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And it's so simple just to do a blood test that you can literally measure your IGF one levels.
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And, uh, we don't really wanna look at IGF one necessarily in I Isolation.
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We do wanna consider a bunch of other markers alongside it, but if we could only ever get an IGF one and we couldn't get the other markers that'll mention in a sec here, it would still be a helpful number to have.
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but we, I don't like looking at things in isolation.
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We have to look at.
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Each of these data points and what they mean to one another and what they mean to your big picture and what do they mean to even a bigger picture outside of you.
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With regards to the general population research.
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So there's a lot of factors in place here.
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Whenever we determine is something truly important or is it less important, but from a base level, we first look at your IGF one.
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Then we're gonna look at other MA markers that are on the blood work that are gonna kind of feed into IGF one two, which would be something like your fasting insulin, your fasting glucose.
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We can also use your fasting insulin, fasting glucose to co to calculate a.
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a, I dunno, a calculation called Homa ir, which tests for insulin resistance and can kind kind of give you an idea of are you completely not insulin resistance? Are you kind of like pre-insulin resistant or are you flat out in insulin resistance? So that gives us even more information than just looking at your insulin or glucose in isolation.
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even more than looking at just your hba one c.
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Hba one C being a reflection of your blood sugar regulation over the past like three months, where fasting glucose is more like what's going on within the last 12 to potentially 48 hours with your blood sugar regulation.
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So if we look at your IGF one, we also wanna get your fasting insulin, your fasting glucose.
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We can calculate your Homa IR from the fasting insulin, fasting glucose, and also look at your hba one C.
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These are kind of like your personal markers here that give us an idea of what's going on in your body currently.
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Then we wanna look outside of that to like, what is your typical dietary habits, your exercise, like what is your overall metabolic health? 'cause a lot of this is feeding into your metabolic health.
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And then overall we wanna look at the big general research of like, what is the role of IGF one in cancer? And then with all that information we determine like, yes, your IGF one being high even despite your insulin and glucose being normal or low, or whatever it might be is something that we wanna tackle.
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I hope that kind of gives you a little bit of an idea here.
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But basically I just wanna point out that just having a high IGF one is not cause for panic.
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There are other things that your body is really good at compensating with when it comes to other markers, other parts of your plan, other parts of research, things like that that can pertain to cancer.
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So I don't want anyone to get super overwhelmed if they were to get their IGF one done and it's high and they're like, oh my gosh, this is like, this is it.
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This is what's feeling fueling my cancer.
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The cancer, I just really gotta get on this.
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It's okay.
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Take a deep breath.
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We can move through this and check other factors as well.
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We definitely wanna work on it, but I don't want any, anyone to go into full panic mode for sure.
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So just a simple test.
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We can do IGF one, we can do those other blood work parameters too, when it comes to blood sugar regulation and some potential growth factors.
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There's a bunch more, I won't get into them too much today, but that's kinda like the core parts of the blood sugar insulin balance.
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And why are we not typically testing this from an oncologist standpoint? Honestly, it's not conventionally recommended.
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It's not really seen to test IGF one outside of growth disorders because my, my true feelings are that your medical team is so focused on making sure that you don't have a disease.
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That looking a little bit further in terms of what can we do for the environment in order to not create a recurrence or to create overall optimal health in order to not get disease again, is really like above and beyond their brain power.
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I could not imagine.
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Working as an oncologist and knowing all of those medication doses and treatment, pathways based on specifics with regards to everything from their, the person's gender to their age, to their blood work like liver functions.
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To their other medications that they might be taking.
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Like that is a lot for any human to understand and then to have to go and figure out like what can we do to change their nutrition, their stress levels, their sleep, their inflammatory levels, all of these things.
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That is a lot of work.
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So I truly don't believe that it should fall within the realm of conventional medicine.
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This is truly where functional medicine can pick up the pieces and really focus in on the next stage, which is of course, the recovery and recurrence prevention aspect.
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So we are seeing a lot of more emerging risk research in integrative oncology showing that it might be a valuable bio biomarker to assess for like someone's cancer recurrence risk.
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if we see people come in with high IGF ones, then there's a lot that we can do from a nutrition lifestyle perspective as an integrative practitioner to help to create this environment where cancer doesn't wanna come back over time.
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So, again, I truly don't feel like it, it should fall within the realm of conventional medicine.
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I do feel like it is more something that us functional doctors have more brain space to learn all of this and keep on top of the evidence and dig a little bit deeper with the person in front of us, more time, things like that.
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But not only can you test IGF one on blood work, there's also different types of IGF one.
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I have to say, it's pretty rare that we see the, what's called isoforms of IGF one get done on people's blood work.
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mostly it's used in research, but we have had a couple clients come in, maybe just a handful.
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Where they had their IGF one, but then they also have it broken down in the different isoforms, which is pretty cool.
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So I will run through them, but I don't expect, we never even recommend or ask that our clients go and get this I the isoforms done at the IGF one.
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It's mostly just that we're looking at the total IGF one, but I'm gonna go through it 'cause I think it's pretty cool.
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there's just like, there's certain parts of it, so certain forms, isoforms that can pertain to different parts of your health and your body that we'll run through right now.
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There's this thing called IGF one ea, which is the most common, the the one that's in your blood in the most amount, the highest amount.
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And IGF one EA is involved in muscle repair and general growth.
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So I'll tell you a little story of someone I knew who she was very much into CrossFit and she would exercise every day and she had gone through a cancer.
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I'm, I'm not gonna go through too many details, but we asked her to get her IGF one done and it was always high and we figured because, we'll again, we'll go through in just a minute here.
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We did know that your IGF one can be raised because of exercise in excessive muscle turnover and things like that, because.
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One, if you're going through a lot of exercise, you're damaging your muscle tissues and we gotta build that back up.
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And as I mentioned earlier, IGF one is one of those things that goes in and helps to build muscle.
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So we anticipated her IGF one actually being high.
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I actually said to the coach who was her, who, who was her coach that don't be worried about her IGF one being high.
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Let's just see where it's at and then we'll go from there.
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But it was like super high and we didn't love it.
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Um.
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We figured and we couldn't get the isoforms done for her, but we did figure it was because of the exercise.
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So if this is you, if you are someone who's a very avid exerciser and you're wondering if potentially maybe you've gotten it done already, you had your IGF one measured and you're like, perhaps it's because I've been exercising so much.
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We did have to recommend that she stopped exercise for about three days to get her IGF one redone again, and it did go down.
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It didn't go down into the normal ranges that we loved.
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It did go down.
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We just had a conversation around the balance of what you can manage outside of exercise.
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'cause she loved her exercise and we didn't necessarily wanna take it away from her.
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We did have a conversation around the roles of IGF one and the growth factor impact of it, how most likely it's high because of the exercise she was doing potentially that she might want to look at the total exercise that she is doing and what would be her thoughts around reducing that or trying different forms of exercise in order to get her IGF one down down.
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Which is super rare that we have to ask someone to kind of reduce their exercise.
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It's usually about us encouraging people to do more exercise, but everyone's very unique.
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So we had a conversation around it and I think she did decide that her exercise routine was a little bit hardcore and she was no longer doing competitions and things like that, so it was more just a habit for her.
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And, so we, we looked at, we just followed up with her numbers over time.
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But anyway, I went a little bit off course there, but I just think it's nice to hear some stories of other people and some approaches that we can take for those situations, but.
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So that's IGF one.
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Ea, which is involved in muscle repair and general growth.
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There's also IGF one, ec, it's also called MGF, or Mechano Growth Factor.
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And this one in particular is something that has been shown in research potentially.
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If, if it's higher, then it might be something that's gonna be promoting cancer cells, survival and proliferation.
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So it might be encouraging the cancer cells not to die, and it might be encouraging them to grow more.
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So that's the IGF one.
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EEC or MGF or mechanical growth factor.
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Isoform and then we've got IGF one eb, which is still being researched.
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It may influence immune signaling and regeneration, but again, it's still kind of being researched there.
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We're trying to figure out what is its role exactly, and honestly we, we, again, we've always seen the isoforms in a couple of of clients.
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Generally looking at IGF one is good.
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Potentially if I had the opportunity in that person who is exercising excessively, I would've loved to see the isoforms, but it just wasn't possible for us to get ordered.
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So her IGF one being high, we could potentially assume that it was the IGF one ea, the muscle growth one.
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Ideally we would've wanted to see was IGF one EC impacted too? And it might've been even a little bit high just because they're, they're very much related to one another and one being high might bounce off and increase another one.
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But in general, we just wanted to get her IGF one lower over time.
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And same for you guys listening to is we wanna see where are your levels at, just your IGF one level in general, and try to reduce that over time.
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So, yeah, most standard labs don't necessarily go into the isoforms of the IGF one.
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But we, we are fine with just looking at someone's IGF one in general, and it's just in the research where they're starting to break that down a little bit more.
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So you might read some papers where they're looking at the different forms, for many different reasons is why they're, they're looking at that.
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So what does high or low? 'cause we've seen some low, uh, IGF one levels as well.
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So what are the high or low levels mean? High IGF one levels.
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What it could often mean is that someone might have an increased risk of recurrence.
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So this is kind of like in our mind, this is our job, is we wanna look at what can we do to reduce someone's risk of recurrence.
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We're gonna look at their IGF one and see, let's get that lowered basically.
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But really IGF one can be linked to a couple different things and the reason it might be high, which is increasing recurrence risk, might be due to other factors.
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And we can look at those other factors and see what are the root contributors.
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And some of the root contributors might be that you might be insulin resistant.
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So we need to look at what can we do to make your, your insulin resistance go away or make your make body less resistant to insulin.
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I'm looking at your blood sugar regulation and there's a lot of different things we can do for that from.
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Blood sugar, balanced meals to better muscle building and exercise, which seems a little counterintuitive, intuitive, but trust me more exercise is gonna potentially lower your IGF one.
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In most ca cases, it's only when someone's like excessively working out that it might increase their IGF one.
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That Goldilocks effect too, right? We don't want too much or too little.
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We can also see, with blood sugar regulation, like people who exercise enough blood sugar balance meals.
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just looking at their glucose, their insulin markers, hba one C, is there anything we can do to make sure that someone's body is processing carbohydrates or do we need to lower the carbohydrate levels? Certain therapeutic diets at certain points, like a, a healthy keto diet for a short term to see if that can impact their insulin as well, and, and then therefore their insulin like growth factor.
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But basically high IGF one is often linked to insulin resistance.
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We really wanna look at it because it is associated in research with faster tumor progression in some cancers.
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And I will, I will put some studies into the show notes there where they're actually looking at humans.
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And the, they're measuring their IGF one levels and seeing that people with higher IGF one compared to people with normal IGF one tend to have a higher, growth of their, their their tumor basically.
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So I'll put some links into the show notes there for you for those papers.
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But ig IGF one, we wanna tackle it.
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It might be encouraging more cancer growth and we wanna look at tackling it from.
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Different perspectives.
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One of 'em being looking at insulin resistance and your blood sugar regulation.
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And I'll give you some more specific, uh, ideas on how to bring the IGF one down in just a minute.
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So, like I said, we sometimes do get low IGF one.
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Which could indicate potentially under nutrition, like you're not eating enough foods in order to encourage cell healing and the, the release of IGF one.
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So we wanna make sure, 'cause we, we do have some clients who come to us and they're so afraid of all the foods that they're really limited in what they eat.
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They're skipping meals a lot of times 'cause it's just so frustrating and scary for them to put certain foods in their mouth that they just are deciding not to eat because that is less anxiety provoking.
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And I totally get the reasoning behind that 'cause of all the.
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Misinformation and fear-based information being thrown in your face when it comes to food and cancer specifically.
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But also we wanna make sure that you're eating enough to fuel your body because if we see low IGF one, it could be that or just undernourished, basically low IGF one can also be an indication of aging.
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It does go lower as we get older 'cause we have less repair and regeneration and things like that to do.
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And then honestly like some people are just genetically predisposed to having a little bit a lower IGF one.
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Like it's just somewhere in their genetics where it's just normal and natural for them to have low IGF one.
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And we have had clients who we just kinda had to come to the conclusion where their IGF one is most likely low because of some genetic predisposition that we don't really know about because they weren't very old and they were eating very well.
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So it was most likely just something that their body was built to have low IGF one, which.
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Maybe that's even protective for a cancer response.
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I don't know.
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I, that is more kind of my personal opinion, that if someone doesn't tend to produce a lot of IGF one, then potentially we're not fueling a lot of cancer growth.
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But who knows? just don't have that information just yet.
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But overall, we wanna look for a balance.
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So we wanna make sure that's not excessively high for sure.
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But, if we can do anything to improve it being low, if it's due to being undernourished, then that's gonna be beneficial for your overall body and healthier body as well.
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So we wanna get that IGF one into nice normal ranges.
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And what are those ranges? So your optimal ranges for IGF one, it does vary based on kind of like whatever lab you're getting your levels done by.
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Done from and also your age.
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But in general, whenever we're analyzing someone's blood work, we are looking at women who are post-treatment.
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We're aiming for like a low normal, around a hundred to 150 nanograms per mil of of their IGF one levels.
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Too low.
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We're thinking like under 80.
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We wanna see is there malnutrition, could it just be due to the age? 'cause we do work with some women who are in their seventies and eighties and maybe even a little bit all above that.
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Although most of our clients are probably 40, 50, 60.
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But if it's too high, we're looking at like 200 and above.
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Really.
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that might suggest that you might have an elevated risk factor for encouraging cancer cells to grow.
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Again, there's so many other factors in place here that we don't wanna just look at it in isolation, but we definitely wanna make sure if your IGF one is high, then we're gonna get the insulin, the glucose HVA one C, even cholesterol markers, all these kind of other markers tested when it comes and inflammatory markers, test it in order to see like, is this an actual problem for you? And of course, we're gonna tackle it even if everything else looks normal.
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We're gonna start looking at your IGF one and some things that we can do in order to bring that down.
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So speaking of what are those things that we can do to bring the IGF one levels down? We want to look at one, testing your insulin, and then if it's high, then we're gonna look at lowering the insulin, which is a big factor.
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There's many different approaches to this.
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One of them being just looking at air, blood sugar, and increasing exercise.
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And certain supplements, like berberine, for example, might help with your blood sugar at insulin levels.
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If we look at managing weight, we wanna look at the overall fiber intake.
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The foods you're eating, antiox, oxygen support, all these different things are all gonna play a factor in lowering the insulin, which will therefore lower the IGF one.
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Another thing that can increase your IGF one is your protein intake.
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So especially like excessive animal protein intake.
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If you are in poor metabolic health in particular, meaning that like you might be a little bit overweight, you might have high cholesterol issues, high inflammatory markers.
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Maybe, you're struggling with fatty liver disease and you do, you can have fatty liver disease and still be healthy weight and everything like that as well.
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So fatty liver disease can be a little bit of a beast of its own, but having, fatty liver disease or poor metabolic health in general, um, and then excessively eating a lot of animal protein might encourage your IGF one levels to go up high.
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So how do we manage that? We might look at making sure that you're still getting your normal, um, adequate amounts of protein to fuel your body.
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But looking at other sources of that protein, can we go maybe even towards more fish or, like legumes, your chickpeas, your lentils, your, your vegetarian source of protein.
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And we might even consider a kind of therapeutic short-term diet where we might go specifically plant-based for a couple of weeks and see, do is, does that drastically bring down your IGF one levels? Never would I feel the need to encourage someone to a hundred percent commit to like any specific diet for life.
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we kind of wanna trial some things out like a, a diet out on a therapeutic level sometimes, which might mean we do a a healthy keto diet for a short term in order to see can we boost someone's metabolism.
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Insulin levels, IGF one, things like that.
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And then after we get our blood markers to where we want them to be, we can then transition them into more of a long-term sustainable diet plan that works for them, that opens up their horizons on what they can eat and enjoy and things like that.
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So I don't feel like we've ever had to keep anyone specifically on a keto diet or a plant-based diet if that wasn't their chosen preference.
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we typically will put them on it for a short term as what we call a therapeutic diet in order to.
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Meet a certain goal for what we wanna see when it comes to their blood levels changing or um, symptoms changing, whatever that might be.
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So what else can influence and help to bring down your high IGF One would be your caloric intake and even something like fasting.
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So if we can get someone into healthy caloric levels for what their body needs in order to thrive, can get them into a fasting window, meaning that they're not eating for a certain time, typically overnight, or they're eating within a certain time, throughout the day.
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Then that can help to reduce IGF one Again, all shown to be beneficial in human studies.
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A lot of these research articles or research studies are done in like people with diabetes or high cholesterol, things like that.
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But we know that if people do these like a fasting overnight, then we, they can see an improvement in their IGF one levels.
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Can kind of, we interpret that to be a benefit in a cancer prevention aspect.
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So if their IGF one is high, if we can get that down, that is gonna help to reduce the risk of cancer growth and things like that as well.
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Even though the studies are done in like diabetes or high cholesterol.
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Another thing that is helpful is we're bringing down IGF one is exercise.
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So I know I told that story of someone who exercised excessively.
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So too much exercise can bring the IGF one up.
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But too little exercise can also bring it up so we can get a little bit of resistance training, muscle building to an adequate amount.
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And it, it doesn't have to be super fancy.
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You don't have to be like, well, how much is that? You'll know, you'll know that you're not overdoing it, that you're not in, you're not kind of in bodybuilding competitions and things like that.
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Like that might be a little bit too excessive.
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Depending on you, depending on your person, depending on the goals.
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But we just want get to get people exercising according to like the normal recommended it daily or weekly amounts for reducing cancer risk.
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And that's where we're gonna see healthy IGF one levels as well.
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So usually it's like two to three times a week for about 60 minutes each time.
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where we're seeing some people build, do, do some muscle building activity, resistance training, a little bit of cardio, things like that.
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And then just general walking outside of that or anything from like a lower activity like yoga, but we want a nice balance of.
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Resistance training, muscle building, weightlifting, things like that.
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And then also some of the other stuff like movement to get the blood flowing, like yoga and walking.
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a little bit of cardio too, if you're doing a little bit more, like more lunges and things that get your heart rate going whenever you're even doing some of your weight training as well.
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It's a, it's a nice mix.
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It's not just one or the other.
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And honestly, just start where you can when it comes to your exercise.
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I won't get too much into that, but there's so much I could talk about when it comes to exercise for sure.
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So, yeah, so exercise resistant training may improve IGF one levels if they're too high.
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and then the other thing is growth factors, or sorry, growth hormones.
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So I mentioned earlier that IGF one is often increased due to another hormone called growth hormone.
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honestly, the reason or the way that you lower growth hormone is you just get older.
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The best.
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Yeah, the best way we can do is just to get older.
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'cause aging just reduces growth hormone overall.
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So I wouldn't say that this is a controllable factor when it comes to lowering your IGF one.
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I just want to make you aware of it that as people get older, their growth hormone gets produced less 'cause there's less growing to do and then that is gonna reflect back on lowering their IGF one as well.
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But again, I don't recommend people just try to get older faster.
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it's just something I want you guys to know.
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It's not a controllable factor.
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Then genetics can sometimes just make people more predisposed to having lower IGF one factor.
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So if you are, um, if you are getting your IGF one measured and it is low, and you're like, well, I'm not malnourished.
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I'm eating a lot and I'm not really that old, then it could just be a genetic kind of reason as to why your IGF one is low.
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And I just wouldn't really worry about it too much.
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So basically what can you do to balance it? Just kind of recap, is we can eat in a way that balances blood sugar.
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You have your protein, your healthy fat, your fiber at each meal.
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You overall reduce your carbohydrate consumption.
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a a general, like a very general benchmark would be to make sure that your carbohydrates your consumption of heart carbohydrates is like 20% or less of your total caloric intake, which some dieticians and.
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Nutrition people think that's actually quite low, but that's not including like necessarily your fibers and things like that.
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So we're looking at the 20% of your total calories comes from carbohydrates.
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It, it is a little bit low and it's a little bit of a stretch for some people, but it's just like a benchmark goal when it comes to helping with insulin resistance and, metabolic health.
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The other thing is we want to make sure that we're reducing excessive.
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Animal protein intake, maybe focusing more on plant-based proteins.
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Fish.
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I know fish is technically kind of like an animal, but it's like a nicer source of protein that's a little bit easier on your body in terms of like the omegas and the, like, the healthy fats that are in the fish.
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It's a little bit just better for your metabolic health.
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the other thing is, there's a couple papers just showing that whey protein, insul ray whey protein isolate or whey protein powders may potentially increase IGF one.
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But, this is in a diabetic population.
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Again, it might not be totally applicable to you.
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So we do overall encourage people to look at other types of protein powders, especially if their IGF one is high.
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That's, we look for ones that are not whey protein and look at other, other forms of the protein.
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But I wouldn't worry about this unless you actually test your IGF one, see that it's high, and then maybe we would look at switching, uh, switching you out from a whey protein powder in general.
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I won't go too much into protein powders.
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In fact, maybe it's a good.
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A good topic for a different episode.
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I wouldn't necessarily, we, we often get people to stay away from whey protein powders anyway.
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Just mostly because I feel like we should be looking at more plant-based proteins.
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Of course we want to avoid soy protein isolates 'cause it's a little bit wishy-washy in terms of what its impact is on hormones and things like that.
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So we don't often have a lot of our clients on whey protein powders, unless like it's the only one that's palatable to them.
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It's the only one that tastes good.
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We do tend to encourage and we have certain suggestions when it comes to more plant-based protein powders.
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We can also avoid snacking constantly, giving your body a break from, breaking down food and insulin being raised and stuff like that.
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And that's gonna help to reduce growth signaling and IGF one on movement, like resistance training I alluded to.
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fasting can help reduce it.
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And then focusing on anti-inflammatory foods, color, ve colorful vegetables, omega threes.
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Even spices like turmeric can potentially help with your inflammatory levels and your growth factor levels and things like that.
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and honestly I want you to use the lab to, to kind of guide decisions and not just come at it from a place of fear and just automatically assume that your IGF one is done or is as high and you need to kind of work on all of these things.
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We definitely wanna get an idea of where is your IGF one on blood work before we start to incorporate many of these changes.
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'cause it might not be of importance to you.
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It might not be something you need to focus on.
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Maybe there's something else that could use your attention instead.
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And, we don't want to get caught up in what could be.
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And let's instead focus on what is important for you.
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So I know how easy it is to feel afraid whenever I talk about a marker that is cancer promoting.
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But I just want you to also remember that these are tools.
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These aren't the end all, be all.
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They cannot be used in isolation.
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And a lot of what I talked about today is stuff that we can actually make a difference with.
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It's not just like, it's high forever.
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What am I gonna do about it? Nothing.
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00:35:20,758.8616863 --> 00:35:26,78.8616863
There's a lot of things that we can change that have been shown to have drastic impacts on your growth factor levels here.
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Something like growth factor one.
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and honestly, it doesn't define your future to have high GF one.
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High IGF one.
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It's, it's just a piece of a bigger puzzle.
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So let's see where it's at and then go from there.
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And I also wanna remind you that you're not just here to block a recurrence or to kill cancer or to stop cancer.
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You're here to figure out how can you live fully past cancer and not always have to do something because of cancer? So there's a different approach here that we wanna see where are your numbers before we go all haywire and try to do this, that and the other thing.
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And to also see lowering IGF one is A, is a helpful impact as well, not just to kill cancer.
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'cause it can help in many different ways.
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So if you do wanna learn more about interpreting your IGF one, looking further into different aspects of blood work in order to figure out what is the most important nutrition plan, where should I focus my attention when it comes to my supplements or my exercise, or just basically your time, energy, money, work can be a very helpful place to start, to start with.
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It's a very foundational approach to creating a plan to help you to feel better, faster, and to reduce your risk of cancer coming back.
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So I absolutely love talking about blood work and I've put together a whole training on it.
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right now I'm just kind of calling it for short, my Blood Work bootcamp, and you can join that.
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I'll put the link to signing up into the show notes.
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It's coming up very soon and I can't wait to do it.
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It's gonna be over a couple of days.
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We're gonna make a big party out of it.
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We're gonna learn a lot about what are the things that you wanna test for on your blood work.
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Why are they important in terms of your general health and cancer recurrence prevention? And also what can you do in order to make these more optimal as opposed to.
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Out of range or just okay ranges.
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We wanna get them all optimal in order to create this environment in your body where cancer doesn't wanna be.
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So if you wanna learn more about that, go over to the show notes and I'll have that link there to sign up.
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But that's all I have for you today.
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I hope that was helpful.
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We went through what is IGF one we went through, what makes it higher? What are the optimal ranges? What can we do to manage it? And if you do wanna learn more, then I do have that blood work bootcamp coming up that you can sign up for.
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Alright.
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That's all I have for today.
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I hope you have a wonderful week, and I'll see you soon.
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Thank you so much for joining me today on the Flourish After Cancer Podcast.
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If you love this episode, please be sure to leave a review and subscribe so you never miss an episode.
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Sending all my best your way, Dr.
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Megan.