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April 26, 2025 31 mins

Episode Overview: In this special episode, recorded during the MRCT Center’s October 2024 conference, Advancing Pediatric Platform Trials: Streamlining Development, Maximizing Impact, we feature a keynote conversation with Dr. Danny Benjamin—renowned pediatrician, researcher, and champion of clinical trial innovation.

Dr. Benjamin discusses how platform trials can address persistent gaps in pediatric therapeutic development and why a coordinated, multi-stakeholder approach is critical to success. His insights, drawn from decades of leadership in this space, speak directly to the opportunities and operational challenges detailed in the MRCT Center’s post-conference report.

Key Discussion Topics:

  • Why traditional clinical trial models often fail pediatric populations
  • The case for multi-arm, multi-sponsor platform trials in rare and common childhood conditions
  • Governance and operational infrastructure to support long-term trial viability
  • Lessons learned from the Pediatric Trials Network and other collaborative efforts
  • The importance of global alignment, data sharing, and ethical considerations in trial design

Learn More: Explore the full Executive and Full Reports from the October convening: 🔗 Advancing Pediatric Platform Trials: Streamlining Development, Maximizing Impact

About the Guest: Dr. Danny Benjamin is the Kiser-Arena Distinguished Professor of Pediatrics at Duke University and a national leader in pediatric drug development. He serves as Principal Investigator of the Pediatric Trials Network and has been instrumental in shaping evidence-based approaches to clinical research in children.

Subscribe & Share: If you value practical, ethical, and globally relevant conversations about clinical research, subscribe to the MRCT Center podcast. Share this episode with colleagues and visit mrctcenter.org to explore more.

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