The Wellness Zone Podcast

Type 2 diabetes affects nearly 38 million Americans, and nearly 100 million adults are prediabetic. In this episode of the Wellness Zone podcast, Dr. Barry Sears breaks down the growing diabetes epidemic and the staggering toll it’s taking on our healthcare system—and how the Zone diet can help.

In this episode of The Wellness Zone, Dr. Barry Sears takes you on a fascinating journey through the history of fish oil—from 18th-century transatlantic cod trade to the Norwegian innovations that transformed the industry. You’ll even hear why kids in the early 1900s were force-fed spoonfuls of cod liver oil before leaving the house—and how that tablespoon delivered 25 times more omega-3s than the average American gets today.

When you’re awake, your body faces constant wear and tear. Sleep, however, is your body’s prime time for repair, resetting your metabolic processes and preparing you for the challenges of the day. Join Dr. Barry Sears and Mary Perry as they explore the critical connection between sleep quality and metabolic health. 

Polyphenols do more than just give fruits and vegetables their vibrant colors—they have the potential to influence your genes. That’s right, the food you eat can literally turn certain genes on or off. But how does this work? It all comes down to AMPK, the master regulator of metabolism.

The Metabolic Way to Improve Athletic Performance | Dr. Barry Sears

What’s the secret to peak athletic performance? It all comes down to two key factors: energy production and focus.

Join Dr. Barry Sears as he explains how Metabolic Engineering can give athletes the edge they need to perform at their

GLP-1 drugs are now being used to treat addiction. But while GLP-1 drugs can be powerful, they come with serious side effects. The good news? You can achieve similar benefits naturally through Metabolic Engineering®, which is also based on calorie restriction—but designed for long-term health.

From the water you drink to the food you eat, these tiny plastic particles are nearly impossible to avoid. Tune in to learn what you can do to minimize your exposure and protect your health—plus how all this relates back to your metabolism.

Have you ever wondered why centenarians—those remarkable individuals who live to 100 or beyond—are almost never obese? It’s not just a coincidence. Obesity is far more than a number on the scale; it’s a chronic inflammatory condition that speeds up aging and steals away your healthspan—the precious years you spend vibrant, active, and free from disease

There’s no approved drug to treat Alzheimer’s. But your diet can play a crucial role in prevention. Reducing insulin resistance may be one of the most powerful ways to protect your brain. That’s where Metabolic Engineering® comes in. In this episode, join Mary Perry and me to learn how this groundbreaking dietary approach can help lower your risk of cognitive decline and keep your brain healthier for years to come.

Ultra-processed foods often get a bad rap—and for good reason.

But what if we could re-engineer foods we love—like pasta, bread, and pastries—to not only keep their nutrients intact but also activate natural pathways that reduce hunger and inflammation caused by obesity?

Well, we can. It’s called Zone Foods, and it’s not science fiction—it’s science.

GLP-1 drugs are often hailed as ‘miracle treatments’. But what makes them effective isn’t magic; it’s the activation of AMPK. This same metabolic pathway can be naturally activated through diet. Dr. Barry Sears and Maruy Perry dive into how this works and why AMPK might be the key to unlocking better health with less of a need for medication.

How old are you, really? While your chronological age is just a number, your biological age reveals the true state of your body’s health. In this episode of the Wellness Zone, Dr. Barry Sears and Mary Perry explore the intriguing science of epigenetics—what switches our genes on or off—and how it impacts aging.

In this episode of The Wellness Zone podcast, Dr. Barry Sears and Mary Perry break down how your metabolism plays a key role in not just living longer, but living better. Tune in to discover the science behind improving your quality of life, and how small changes today can set you up for a healthier future.

From ancient willow bark to modern aspirin, all the way to today’s GLP-1, we'll explore how these mighty remedies have evolved. And guess what? They all share a secret superpower: activating AMPK!

When you think of menopause, diet might not be the first thing that comes to mind—but it should be. The symptoms of menopause are deeply intertwined with the metabolic shifts occurring in your body.

AGEs are Advanced Glycated Endproducts. AGEs are bad for your health because they contribute to oxidative stress and inflammation, both key factors in the aging process and the development of various chronic diseases.

Welcome to another episode of the Wellness Zone Podcast with Dr. Barry Sears and Mary Perry.

This week we delve into a groundbreaking study that reveals how GLP-1 drugs—those new weight loss and diabetes injectables—may have the potential to turn off cancer cells. But your diet may provide the same results.