Beta blocker overdose is one of the most dangerous cardiovascular emergencies, leading to bradycardia, hypotension, seizures, and cardiogenic shock. Agents like propranolol, metoprolol, carvedilol, and atenolol can cause life-threatening toxicity, especially with ER formulations or co-ingestions.
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In this podcast, we cover: What beta blockers are and why overdoses are so dangerous π Mechanisms of toxicity: Ξ²1/Ξ²2 blockade, sodium channel blockade, lipophilicity, and QT prolongation π¬ Clinical presentation: bradycardia, shock, seizures, bronchospasm, hypoglycemia π©Ί Emergency management: airway/IV access, glucagon, HIET (high-dose insulin therapy), vasopressors, sodium bicarbonate, lipid emulsion, ECMO π Diagnostic workup and monitoring strategies in the ED/ICU Prognosis, pearls, and practice questions for learners
Link To Video Version:https://www.youtube.com/watch?v=Y2zwZl323j0
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