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October 4, 2025 โ€ข 33 mins

Beta blocker overdose is one of the most dangerous cardiovascular emergencies, leading to bradycardia, hypotension, seizures, and cardiogenic shock. Agents like propranolol, metoprolol, carvedilol, and atenolol can cause life-threatening toxicity, especially with ER formulations or co-ingestions.

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In this podcast, we cover: What beta blockers are and why overdoses are so dangerous ๐Ÿ’Š Mechanisms of toxicity: ฮฒ1/ฮฒ2 blockade, sodium channel blockade, lipophilicity, and QT prolongation ๐Ÿ”ฌ Clinical presentation: bradycardia, shock, seizures, bronchospasm, hypoglycemia ๐Ÿฉบ Emergency management: airway/IV access, glucagon, HIET (high-dose insulin therapy), vasopressors, sodium bicarbonate, lipid emulsion, ECMO ๐Ÿš‘ Diagnostic workup and monitoring strategies in the ED/ICU Prognosis, pearls, and practice questions for learners

Link To Video Version:https://www.youtube.com/watch?v=Y2zwZl323j0

DISCLAIMER THIS PODCAST DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, audio, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.

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