Sympathomimetic Toxicity Explained | Cocaine, Meth, MDMA & Stimulant Overdose

Sympathomimetic toxicity is a common emergency medicine presentation, often caused by cocaine, methamphetamine, MDMA, and stimulant medications. These cases can mimic other toxidromes and may progress to life-threatening hyperthermia, arrhythmias, seizures, or multi-organ failure.

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In this video, we cover: What sympathomimetics are and common agents (cocaine, meth, MDMA, stimulants) 💊 Mechanism of toxicity: catecholamine excess (NE, dopamine, serotonin) 🔬 Clinical presentation: agitation, tachycardia, hypertension, diaphoresis, chest pain, seizures 🩺 Diagnostic workup and differentiating from anticholinergic toxidrome ED/ICU management: benzodiazepines first line, cooling, fluids, avoid pure β blockers 🚑 Complications: rhabdomyolysis, hyperthermia, ACS, stroke, hyponatremia Prognosis, pearls, and practice questions for learners

Link To Video Version:https://www.youtube.com/watch?v=UL_YJ6oOZNY

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