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November 7, 2024 60 mins
Un nouvel épisode du Pharmascope est disponible! Dans ce 145e épisode, Nicolas, Isabelle et Olivier essaient de ne pas trop vous faire trembler en revisitant une vieille littérature et un problème incommodant : le tremblement essentiel. Les objectifs pour cet épisode sont les suivants: Expliquer l’épidémiologie, la présentation clinique et l’évaluation du tremblement essentiel. Conseiller des mesures non-pharmacologiques pour aider les personnes avec un tremblement essentiel. Discuter des bénéfices et des désavantages associés aux principaux traitements pharmacologiques du tremblement essentiel. Ressources pertinentes en lien avec l’épisode  Shanker V. Essential tremor: diagnosis and management. BMJ. 2019 Aug 5;366:14485 Welton T, Cardoso F, Carr JA, Chan LL, Deuschl G, Jankovic J, Tan EK. Essential tremor. Nat Rev Dis Primers. 2021 Nov 11;7(1):83. Baizabal-Carvallo JF, Morgan JC. Drug-induced tremor, clinical features, diagnostic approach and management. J Neurol Sci. 2022 Apr 15;435:120192 Ferreira JJ et coll. MDS Task Force on Tremor and the MDS Evidence Based Medicine Committee. MDS evidence-based review of treatments for essential tremor. Mov Disord. 2019 Jul;34(7):950-958. Serrano-Dueñas M. Use of primidone in low doses (250 mg/day) versus high doses (750 mg/day) in the management of essential tremor. Double-blind comparative study with one-year follow-up. Parkinsonism Relat Disord. 2003 Oct;10(1):29-33. Bruno E, Nicoletti A, Quattrocchi G, Allegra R, Filippini G, Colosimo C, Zappia M. Topiramate for essential tremor. Cochrane Database Syst Rev. 2017 Apr 14;4(4):CD009683. Ondo WG, Jankovic J, Connor GS, Pahwa R, Elble R, Stacy MA, Koller WC, Schwarzman L, Wu SC, Hulihan JF; Topiramate Essential Tremor Study Investigators. Topiramate in essential tremor: a double-blind, placebo-controlled trial. Neurology. 2006 Mar 14;66(5):672-7. Bruno E, Nicoletti A, Quattrocchi G, Filippini G, Colosimo C, Zappia M. Pregabalin for essential tremor. Cochrane Database Syst Rev. 2016 Oct 20;10(10):CD009682 Bruno E, Nicoletti A, Quattrocchi G, Filippini G, Zappia M, Colosimo C. Alprazolam for essential tremor. Cochrane Database Syst Rev. 2015 Dec 6;2015(12):CD009681. Marques A et coll. Trial of Botulinum Toxin for Isolated or Essential Head Tremor. N Engl J Med. 2023 Nov 9;389(19):1753-1765. Yetimalar Y, Irtman G, Kurt T, Başoğlu M. Olanzapine versus propranolol in essential tremor. Clin Neurol Neurosurg. 2005 Dec;108(1):32-5.
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