The Straight and Marrow
A show that discusses all things Allogeneic bone marrow transplant. From pre transplant considerations to survivorship using experiences of health care professionals patients & carers with current evidence to keep it straight. The Straight and Marrow podcast is sponsored by ARROW, the Bone Marrow Transplant Foundation.
Episodes
In this deeply personal episode, we sit down with Chantelle, a patient who underwent CAR T-cell therapy after exhausting other treatment options. They share the highs and lows of the experience — from the decision to proceed, through the infusion and side effects, to the long and uncertain road of recovery. With honesty and clarity, this story sheds light on what it’s really like to live through one of the most cutting-edge cancer...
Dr Katherine Cummins (Haematologist at the Peter MacCallum Cancer Centre and The Royal Melbourne Hospital with a focus on clinical translation of CAR T-cells and Allogeneic Stem Cell Transplantation) joins Alex and Hannah to discuss the long term complications post CAR T, focusing on infections. Katherine discusses the impact of lymphodepleting chemotherapy and what that means for low blood counts, infection risks and how we can t...
Nicole O'Leary - an experienced CAR-T nurse practitioner - discusses the importance of the role of the carer. CAR T therapy is not a solo journey and in this episode, we shine a light on the unsung heroes: the carers. From managing medications and monitoring for side effects to providing emotional support through the highs and lows, carers play a critical role in the success and safety of CAR T treatment.
Dr Valeriya Kuznetsova, a neuropsychologist, joins the Straight and Marrow team to discuss the neurological side effects of CAR T cell therapy, including ICANS (immune effector cell-associated neurotoxicity syndrome). From confusion and seizures to subtle cognitive changes, we explore how these toxicities manifest, why they occur, and what can be done to monitor and manage them. Tune in as we navigate the intersection of cutting-e...
CAR T-cell therapy is revolutionising cancer treatment, but it comes with unique side effects that every patient and caregiver should understand. In this episode, Dr Hamish Scott joins Alex and Hannah to break down the most common side effects, including cytokine release syndrome (CRS) and neurological toxicities, explaining how they present, how they’re monitored, and what can be done to manage them. Whether you're a patien...
Have you ever wondered how CAR T Cells are made? Join us for a look behind the curtain of CAR T manufacturing with esteemed scientist Associate Professor Dominic Wall, an acknowledged expert in the field and Chief Scientific Officer of Cell Therapies Pty Ltd.
Shae Disney - an expert Apheresis nurse - talks to Hannah and Alex about what to expect when your cells are being collected, from vein assessments to buffy coat and citrate toxicity as she maps out the journey of the cells from collection to infusion.
Harnessing Immunity: The CAR T Story is your guide to one of the most ground breaking cancer treatments of our time. This podcast season unpacks how CAR-T therapy is revolutionizing immunotherapy, giving T-cells the power to seek and destroy cancer like never before. From the science behind it to real patient experiences, expert insights, and the latest research; Hannah, Alex and Yvonne break down what you need to know about this c...
When it comes to skin/cutaneous GVHD, it takes more than thick skin to face the challenges. In this episode, we uncover the layers of this condition—its causes, treatments, and the impact on daily life. With insights from medical experts with a wealth of experience, we peel back the complexities to help you navigate life with skin GVHD, one step at a time.
In this episode, we take a deep dive into pulmonary graft-versus-host disease (GVHD), a complex and potentially life-altering complication of Allogeneic Stem Cell Transplantation. Discover how GVHD impacts the lungs, leading to symptoms like chronic cough, breathlessness, and reduced lung function. Featuring expert interviews with pulmonologists and transplant specialists, we explore the latest diagnostic tools, treatment strateg...
Join us as we explore the intimate and often overlooked topic of vaginal graft-versus-host disease (GVHD). This episode delves into the physical, emotional, and medical challenges faced by individuals experiencing this condition after a stem cell transplant. With insights from Dr Jennifer Bradford (Gynaecologist), we’ll discuss the symptoms, treatment options, and strategies for improving quality of life. Whether you're a pat...
Join us for an insightful episode as we welcome Professor Stephanie Lee, a leading expert in chronic graft-versus-host disease (GVHD). With years of experience as a researcher and clinician, Dr. Lee sheds light on the challenges and breakthroughs in managing chronic GVHD, a complex condition affecting many organs. Stephanie provides an overview on chronic GVHD, the latest treatment advancements, and practical strategies for improvi...
The decision and planning about when and how to return to work or study after an allogeneic BMT can be really stressful. Sometimes you really want to get back into it but you wonder what to tell your employer and colleagues. Then there's the decision about how many hours a day you can manage and how to juggle work, study, medical appointments and how you are feeling physically and emotionally. In this podcast episode Jacinta s...
Be Alert- Not Alarmed. In this episode, Yvonne and Alex talk you through a head to toe chronic Graft vs Host Disease Self Assessment. From prayer pose to fingernails to the digestive system we walk you through possible signs of GvHD and when to escalate to your transplant team.
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Josh and his mum Hazel talk with the Straight and Marrow team about Josh’s bone marrow transplant for lymphoma. They discuss tips, hope, count recovery and post transplant complications to help other people no matter what their role is.
From the tricky and rewarding patient and carer relationship to the differences between a CAR T transplant and an allogeneic stem cell transplant, Josh and Hazel discuss it all
We go straight to the expert on what to eat and why post transplant. Danika Carty, an experienced haematology dietician, dispels the myths of a neutropenic diet and shares strategies on how to manage taste changes, high protein diets and food supplementation.
Our most popular guest returns to discuss the nuts and bolts of the post transplant course after discharge from hospital. Dr Ashvind Prabahran talks about CMV/EBV, GVHD –every acronym in BMT including the risk of infections and medication management.
Our most popular guest returns to discuss the nuts and bolts of the post transplant course after discharge from hospital. Dr Ashvind Prabahran talks about CMV/EBV, GVHD –every acronym in BMT including the risk of infections and medication management.
Dr Shaza Abo talks to the Straight and Marrow team to discuss the benefits of exercise pre, during and post AlloBMT. From ensuring safety to recommended guidelines, Shaza has a wealth of knowledge, resources and experience as a clinical and research physiotherapist.
Richelle and Chris from Arrow the Bone Marrow Transplant Foundation join the Straight and Marrow team to discuss what the charity offers, from financial support, information booklets to scholarships for healthcare professionals – they are here to support all people affected by bone marrow transplants
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