What if your gut issues aren’t just about gluten or food sensitivities?
In this episode, we’re joined by Dr. Alessio Fasano, one of the world’s leading researchers on celiac disease, gluten-related disorders, and the gut microbiome. He's the Director of the Center for Celiac Research and Treatment at Massachusetts General Hospital and a professor at Harvard Medical School.
We dive into the 5 hidden triggers that turn genetic risk into chronic illness—and why most people are looking in the wrong place when it comes to gut inflammation.
You’ll learn:
• Why “leaky gut” isn’t just wellness hype (and what really causes it)• How gluten, zonulin, and microbiome health are connected• The real reason so many people feel better eating bread in Europe• What you can do now to protect your gut and reduce long-term inflammation
If you’ve been spinning your wheels on bloating, brain fog, food sensitivities, or autoimmune flare-ups… this one is for you.
Chapters
00:00 Introduction to Gut Health and Environment
03:48 Understanding Gluten and Its Impact
10:57 Exploring Gluten-Related Disorders
19:12 The Role of Environment in Health
23:57 The Microbiome: A Hidden World
29:23 Future of Gut Health Research
30:51 Understanding the Microbiome and Its Importance
37:56 The Impact of Lifestyle on Gut Health
46:02 The Journey of Scientific Discovery
50:42 Making Sustainable 1% Shifts in Health
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On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!