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July 21, 2025 14 mins

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"When in doubt, use epi." This is the life-saving mantra every person with severe allergies needs to know. 

In this essential "How-To" episode of Allergy Actually, your bestie allergist moms – Dr. Kara Wada, Dr. Amber Patterson, and Dr. Meagan Shepherd – tackle one of the most important and often feared topics: using epinephrine during anaphylaxis.

They discuss why hesitation is common (even for doctors!), explain the crucial new 2023 anaphylaxis guidelines that change what you do after using epi, and provide step-by-step demonstrations for the most common epinephrine devices on the market. From traditional auto-injectors like EpiPen and Auvi-Q to the needle-free nasal spray Neffy, this is your complete guide to using epinephrine with confidence and saving a life.

EPISODE IN A GLANCE
03:20 How to Use: The Generic Auto-Injector (Adrenaclick-style)
05:20 How to Use: The EpiPen ("Blue to the sky, orange to the thigh")
07:57 How to Use: The Auvi-Q (The Talking Auto-Injector)
09:27 How to Use: Neffy (The Needle-Free Nasal Spray Option)
11:46 Future Technology: Anaphylm (The Under-the-Tongue Film)
12:43 What If My Epinephrine is Expired?


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ABOUT HOSTS
KARA WADA, MD
Founder of the Immune Confident Institute. Quadruple board-certified pediatric and adult allergy immunology & lifestyle medicine physician, Sjogren’s patient and life coach shares her recipe for success combining anti-inflammatory lifestyle, trusting therapeutic relationships, modern medicine & our minds to harness our body’s ability to heal.

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AMBER PATTERSON, MD
A world-renowned allergy and immunology expert based in Findlay, Ohio. As the U.S. ambassador for ILIT™, a 3-injection allergy shot protocol, she’s redefining allergy care through her solo-private practice, Auni Allergy®, and the groundbreaking Auni ILIT Learning Network. Dr. Patterson’s leadership extends to nearly a decade on the American Academy of Allergy committee and her role as a clinical assistant professor at the University of Toledo College of Medicine. 

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MEAGAN SHEPHERD, MD
A board-certified allergist and immunologist with nearly 15 years of experience providing personalized care for allergies, asthma, and immunodeficiency. She specializes in advanced immunotherapy and practical, evidence-based treatment strategies to improve quality of life. In addition to her clinical work, Dr. Shepherd is known for her focus on helping patients with allergy-conscious living — designing homes, habits, and lifestyles that support both wellness and comfort.

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